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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Topic 346: Targeted Radionuclide Therapy of Neuroendocrine Tumors Using 212Pb-octreotate Analogs

    SBC: RADIOMEDIX, INC.            Topic: NCI

    A peptide receptor radionuclide therapy (PRRT) using [177Lu]/[90Y]-labeled somatostatin analogs has been proven to induce objective response in 30-45% of patients with advanced/progressive neuroendocrine tumors (NETs). The complete response to beta-emitter PRRT is rare. This is due to the fact that NETs are diagnosed at late stage of disease; the NETs patients with remissions could develop resista ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Topic 379: Extensible and Scalable Platform for Data Integration from Wearable Sensors to Generate Novel Analytics for Cancer Patients

    SBC: Litmus Health, Inc.            Topic: NCI

    The longterm objective of the Litmus Health platform is to allow researchers and clinicians to use data on cancer patients from wearables/sensors and smartphones. Collecting real-time, high-quality data from patients will transform care and clinical trials. Automating data collection, storage, analysis, and interpretation of data will result in better measurement of signs and symptoms and improved ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Topic 372: Highly multiplexed selection of aptamers to hundreds of canine immunotherapy targets

    SBC: Base Pair Biotechnologies, Inc.            Topic: NCI

    The preclinical development of cancer therapeutics, including the recent trend and focus on cancer immunotherapies, is evolving from the traditional use of mouse models to the use of other animal models including canine, rat, and minipig. Each of these non-mouse models carries its own advantages and abilities to increase the clinical relevance of the model as compared to mouse models. Yet, the wid ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Developing informatics tools to make immunology research data Findable, Accessible, Interoperable and Reusable

    SBC: Melax Technologies, Inc            Topic: NIAID

    Immunological research produces complex datasets ranging from molecular level to individuals and populationsSeveral data repositories aim to serve the community by housing and making the datasets available for reuseHowevertheir usage is still limited due to lack of standardizations and accessibilityOne common issue is that the datasets in these repositories are not available to generalized search ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Inhaled Delivery of Clofazimine- A High Efficiency, Flow Independent, Targeted, Low Cost DPI

    SBC: Via Therapeutics, LLC            Topic: NIAID

    Multidrug resistance tuberculosisMDR TBis a global healthcare concern compounded by poor compliance associated with lengthy drug susceptible TBDS TBtreatment regimensClofazimineCFZis highly active against MDR TBbut oral use is limited by systemic toxicityhyperpigmentationGI effectsand QT prolongationInhalation of CFZ will overcome these limitations by achieving high local concentrations of drug an ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  6. A Novel, Nanostructured, Metal-organic Frameworks-Based Product Loss Prevention Technology in the Oil and Natural Gas Sector

    SBC: Framergy, Inc.            Topic: 17NCER2C

    To reach the end user, oil and gas production at the wellhead must be transmitted through the country and distributed to a wide range of customers. This logistical system requires natural gas gathering lines, processing facilities, product storage tanks and lots of other equipment. What results is air pollution caused by industry losses during these operations and the use of continuous or intermit ...

    SBIR Phase I 2018 Environmental Protection Agency
  7. Simplified Miniature Blood Sampler and Preserver for Toxicant Exposure Monitoring

    SBC: Lynntech Inc.            Topic: A17140

    Our service members deployed worldwide are at risk of exposures to local environmental and industrial toxicants which can potentially result in long-term adverse health effects. Understanding the impact of these exposures is critical for improved force protection and safeguarding individual soldier health. Capturing and classifying exposure data is essential for developing and implementing risk mi ...

    SBIR Phase I 2018 Department of DefenseArmy
  8. Innovative Matrix Systems for Carbon Fiber Reinforced Composite Tactical Rocket Motor Applications

    SBC: Texas Research Institute, Austin, Inc.            Topic: A15105

    A composite matrix resin was demonstrated during Phase I that will reduce the cost of structural tactical motor hardware. While the resin was designed specifically for filament winding applications, the technology could easily be transitioned to additional composite fabrication areas. Formulated resin systems were prepared to obtain the desired processing properties and high glass transition tempe ...

    SBIR Phase II 2018 Department of DefenseArmy
  9. Tunable LWIR Notch Filter Metasurfaces

    SBC: NANOHMICS INC            Topic: A16094

    For dynamic protection of LWIR sensors from laser dazzler threats, Nanohmics, Inc., proposes to develop a thin, light-weight, electronically tunable notch filter based on microfabricated graphene-integrated metasurfaces.The optical filter can reject a specific narrow spectral line (notch) or multiple simultaneous notches.The metasurface comprises an engineered array of resonant microstructure nano ...

    SBIR Phase II 2018 Department of DefenseArmy
  10. Electronic grade, single crystal or large-grain polycrystalline diamond wafer development.

    SBC: PLASMABILITY, LLC            Topic: A16021

    The goal of the Phase II program is to demonstrate growth of large-area single-crystal diamond substrates having surface area of 6 cm2 and suitable for electronic device applications. This will represent a major leap in available substrate area, from less than 1 cm2 available today. The technical path will directly follow the work begun in the Phase I program, which is, using our toroidal plasma C ...

    SBIR Phase II 2018 Department of DefenseArmy

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