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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A Novel, Nanostructured, Metal-organic Frameworks-Based Product Loss Prevention Technology in the Oil and Natural Gas Sector

    SBC: FRAMERGY INC            Topic: 17NCER2C

    To reach the end user, oil and gas production at the wellhead must be transmitted through the country and distributed to a wide range of customers. This logistical system requires natural gas gathering lines, processing facilities, product storage tanks and lots of other equipment. What results is air pollution caused by industry losses during these operations and the use of continuous or intermit ...

    SBIR Phase I 2018 Environmental Protection Agency
  2. A High-Throughput, Multi-Omic Assay of Tumor Biomarkers from Single-Cells

    SBC: ISOPLEXIS CORPORATION            Topic: 172

    SUMMARY Although solid tumors oftentimes arise from the uninhibited growth of a single aberrant cellthe population of cells within a tumor are genetically and molecularly heterogenousThis makes it very difficult to evaluate a therapy s efficacy when using bulk population measurementsFurthermorerecent research has implicated microRNAsmiRNAsas drivers of progression and malignancy in many tumor type ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Confocal and Autofluorescence Imaging of Macular Degeneration using a Low Cost Digital Imager

    SBC: AEON IMAGING LLC            Topic: NEI

    Project SummaryAbstract The overall goal of the proposed SBIR Phase II research is to build and evaluate a low costmulti mode retinal camera used to detect and manage causes of macular impairmentAge related macular degenerationAMDremains the most common cause of permanent vision loss in the US and many industrialized countriesTreatments with portable lasers and injectable drugs can save sightbut e ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  4. A Novel Glycosaminoglycan-Based Therapeutic for Chronic Rhinosinusitis

    SBC: GLYCOMIRA, LLC            Topic: NIAID

    PROJECT SUMMARY Chronic rhinosinusitis (CRS) is one of the most prevalent inflammatory diseases in the U.S., affecting up to 16% of the population and substantially diminishing the quality of life and productivity of patients. In four years, the annual U.S. health care expenditure to treat patients with CRS dramatically increased from $9B to $64B (5% of the health care budget), with a correspondin ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Enhanced Recovery of Pharmaceutical Solvent driven by EPA Initiative

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: NIEHS

    Summary Enhanced Recovery of Pharmaceutical Solvent driven by EPA InitiativeThe United States Environmental Protection AgencyEPAis establishing new safeguards for hazardous secondary materials with objectives to promote the economicenvironmentaland public health benefits of recycling wasteswith an emphasis on several industrial sectorsincluding the pharmaceutical industryOn averagepharmaceutical m ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  6. Polymeric nanoparticles for inductive browning of white adipose tissue

    SBC: ADIPO THERAPEUTICS, LLC            Topic: 200

    Global epidemics of obesity and its associated comorbidities pose formidable challenges to human healthCurrent few medications available for obesity treatment only produce modest effects and are usually accompanied with unpleasantpotentially harmful side effectsThere is accumulating evidence that significant metabolic differences that distinguish beige brown adipocytes from white adipocytes can po ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Development of novel small molecule analgesics modulating the nNOS-NOS1AP protein-protein interaction

    SBC: ANAGIN            Topic: 103

    Abstract This application, “Development of novel small molecule analgesics modulating the nNOS-NOS1AP protein- protein interaction,” addresses the critical need for more effective medications to treat chronic neuropathic pain affecting ~116 million people in the United States. Current pain medications such as NSAIDS, steroids, opiates and gabapentin analogs have documented and often severe sid ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Development and feasibility of prevention-minded oral health mobile App based on dietary selections and oral hygiene events.

    SBC: Indiana Nanotech, LLC            Topic: NIDCR

    The number of decayed and filled tooth surfaces in primary dentition is on the rise in US children between the ages ofandyears oldin factof adolescentsbetweenandyears oldandout ofdentate seniorsagebear evidence of dental cariesReinforced with areport statingof those between the ages ofandhave dental cariesvirtually all walks of life are thus affectedand this doesn t even include those unreportedor ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Fluoroscopic drill attachment for orthopedic trauma surgery

    SBC: ECLIPSE ORTHOPAEDICS, LLC            Topic: NIAMS

    Abstract Aboutleg and hip fractures each year are treated by implanting a stiff metal rod or intramedullaryIMnailthrough the center of the bone and fixing the ends of the nail to the bone with screwsBut placing the locking screws to fix the rod to the bone is difficultTo anchor the nail securelythe surgeon must accurately drill pilot holes through both the bone and locking holes in the nailwhile t ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Software and services to advance dose-response modeling in chemical risk assesment

    SBC: KS & ASSOCIATES LLC            Topic: NCATS

    PROJECT SUMMARY Chemical risk assessment has been widely applied in chemical industry as a necessary step to get new commercial chemicals registeredand in governmental agencies as a critical procedure to evaluate the toxicity of chemicals in order to properly regulate them to protect human health and the environmentThe Lautenberg Chemical Safety Act further strengthens the importance of chemical r ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
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