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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Actuated Low-Force Biopsy Tool for Versatile Bone Lesion Access with Less Trauma

    SBC: ACTUATED MEDICAL, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): In this Phase II SBIR, Actuated Medical, Inc. will complete the development of the Actuated Low-Force Biopsy Tool for Versatile Bone Lesion Access with Less Trauma. Public Health Problem: Percutaneous bone biopsy is performed to obtain tissue for specific diagnosis of bone lesions identified through imaging or clinical evaluation. A major disadvantage of the ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  2. Advanced In-Shoe Orthotic Treatment for Foot Pain

    SBC: DIAPEDIA, LLC            Topic: NIA

    DESCRIPTION (provided by applicant): This Phase II SBIR proposal describes a strategy and work plan for accelerating to market a new device that will provide an evidence-based, patient-specific solution to a significant public health problem: foot pain. The TrueContour(R) therapeutic insole system was originally conceived for prevention of forefoot injury in diabetes mellitus. We propose to furth ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  3. Analysis of Circulating Cancer Cells Early in Disease

    SBC: Immunicon Corporation            Topic: N/A

    DESCRIPTION: (provided by applicant) The long term objective of this proposal is commercialization of a test for the management of cancer. Immunicon has developed a sensitive test for detecting tumor cells in peripheral blood. This test uses ferrofluids and magnetic separation technology for tumor cell enrichment and ...

    SBIR Phase II 2001 Department of Health and Human ServicesNational Institutes of Health
  4. A novel diagnostic biomarker for Hepatocellular Carcinoma(HCC)

    SBC: IMCARE BIOTECH            Topic: NCI

    DESCRIPTIONprovided by applicantHepatocellular carcinomaHCCis usually undetected until its later stageswhere theyear survival rate for patients is less thanHoweverthe survival rate can be as high asif the cancer is detected earlyUnfortunatelyearly detection of HCC is not possible with any screening tests that are currently availablesuch as ultrasound or imaging technologiesAlpha FetoproteinAFPwhic ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  5. A WARPABLE DIGITAL RODENT BRAIN ATLAS

    SBC: CHI Systems, Inc.            Topic: N/A

    N/A

    SBIR Phase II 2001 Department of Health and Human ServicesNational Institutes of Health
  6. Biocompatible Coating for Pediatric Blood Oxygenators- Phase II

    SBC: ENSION Inc            Topic: N/A

    DESCRIPTION (provided by applicant): Many oxygenators clinically available for pediatric (and adult) extracorporeal membrane oxygenation (ECMO) utilize heparin coatings such as Carmeda BioActive Surface on device surfaces, including the microporous hollow fibers, to improve biocompatibility. Despite application of these coatings, significant inflammatory and coagulation-related complications, as ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  7. CAD-CAM Technology for Diabetic Footwear

    SBC: DIAPEDIA, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Diabetes remains the leading cause of non-traumatic lower extremity amputations. Most amputations are preceded by a foot ulcer, so that successfully treating, or better still preventing, foot ulcers should reduce the n umber of diabetes related amputations. The majority of foot ulcers in diabetic patients are the result of loss of protective sensation (LOPS) s ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  8. CATHEPSIN L INHIBITORS AS PAN CORONAVIRUS THERAPEUTICS

    SBC: PHELIX THERAPEUTICS LLC            Topic: R

    DESCRIPTION provided by applicant Coronaviruses CoV are RNA viruses that cause gastrointestinal respiratory and neurological symptoms in several mammalian species The outbreak of the severe acute respiratory syndrome CoV SARS CoV in humans was fatal in of infected patients infecting people and killing The recent incidents involving the highly pathogenic Middle East ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  9. Cell-free Detection of GPCR Signaling in a Nanoscale System

    SBC: INTEGRAL MOLECULAR, INC            Topic: N/A

    DESCRIPTION (provided by applicant): G protein-coupled receptors (GPCRs) are one of the most important families of pharmaceutical targets. However, some of the most desirable types of GPCR drugs have also been some of the most difficult to discover. GPCRs are integral membrane proteins that are traditionally studied in live cells or cell membrane preparations, sources that limit the ability to pu ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  10. Clinical Investigation of the Ceramide NanoLiposome for Advanced Solid Tumors

    SBC: KEYSTONE NANO, INC.            Topic: 102

    DESCRIPTIONprovided by applicantKeystone Nanoin partnership with the University of Maryland Greenebaum Cancer CenterUMD GCCproposes a multi site clinical evaluation of the Ceramide NanoLiposomeCNLas a novel anti cancer therapeuticThe overall objective of this project is to advance the CNL through a Phase I clinical trialThe results of this trial will support subsequent trials for the intended init ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
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