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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY21 is not expected to be complete until September, 2022.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. N/A

    SBC: ABRATECH CORPORATION            Topic: N/A

    N/A

    SBIR Phase II 2001 Department of Health and Human ServicesNational Institutes of Health
  2. Scalable tools for the analysis of chemical compounds using graph-based querying

    SBC: Acelot, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Our current capacity to generate chemical and structural biological data far exceeds our capability to meaningfully assimilate it. The data describes molecules and biological macromolecules and associated properties. A principle common to the structure of all chemical and biological macromolecular entities is the composition of objects related by energetic int ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  3. THE APPLICATION OF CHANNELING RADIATION TO NONINVASIVE ANGIOGRAPHY

    SBC: ADELPHI TECHNOLOGY INC            Topic: N/A

    THE PURPOSE OF THIS WORK IS TO CONDUCT AN EVALUATION OF CHANNELING RADIATION FOR THE NONINVASIVE ASSESSMENT OF CORONARY ARTERY DISEASE IN HUMANS. THE HIGH BRIGHTNESS, LASER-LIKE COLLIMATION, LINEAR POLARIZATION, AND QUASIMONO- CHROMATICITY OF CHANNELING RADIATION MAKE IT AN IDEAL SOURCEOF X-RAYS FOR MEDICAL APPLICATIONS. RECENT EXPERIMENTS USING SYNCHROTRON EMISSION AS A SOURCE OF X-RAYS, COUPLED ...

    SBIR Phase II 1989 Department of Health and Human Services
  4. Multiplex Gene Expression in Single Cells for Circulating Tumor Cell Detection

    SBC: ADVANCED CELL DIAGNOSTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The detection and enumeration of circulating tumor cells (CTCs) has the potential to become a very powerful tool in cancer diagnosis and treatment. However, current technologies for CTC detection are not yet established in routine clinical practice. One reason is that CTCs are present in blood at an extremely low concentration of one in 10 million white blood ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  5. Computer-Based Speech-Reception Training

    SBC: ADVANCED HEARING CONCEPTS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): A common complaint by people with hearing loss is the great difficulty they experience in understanding speech in a noisy environment. Hearing aids, unfortunately, amplify both speech and background noise. It is possibl e to improve speech understanding in noise to some extent by honing one's listening skills. A self-guiding training system will be developed to ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  6. TOXICOLOGY/SAFETY STUDIES OF A CHRONIC PAIN THERAPEUTIC

    SBC: Advanced Targeting Systems            Topic: N/A

    N/A

    SBIR Phase II 2001 Department of Health and Human ServicesNational Institutes of Health
  7. A Specific Tool for Targeting Neurodegeneration

    SBC: Advanced Targeting Systems            Topic: N/A

    DESCRIPTION: (Adapted from the Applicant's Abstract) The Mouse is the species of choice for many neuroscientists because of well-characterized molecular biology and chemistry of its brain, the recent widespread use of transgenic and knockout techniques, and the low cost and rapid breeding of the animal. Mice will become more important upon completion of the sequencing ...

    SBIR Phase II 2001 Department of Health and Human ServicesNational Institutes of Health
  8. Enhancing in vitro Cartilge Synthesis for Human Therapy

    SBC: ADVANCED TISSUE SCIENCES, INC.            Topic: N/A

    DESCRIPTION (Provided by Applicant): The long-term objective of this proposal is to generate a cartilage product with mechanical properties comparable to those of adult articular cartilage for the repair of focal articular defects. Based on previous experimental findings, our hypothesis is that mechanical loading will improve the growth of tissue engineered cartila ...

    SBIR Phase II 2001 Department of Health and Human ServicesNational Institutes of Health
  9. SITE-DIRECTED DRUG DESIGN AGAINST PLASMODIUM FALCIPARUM.

    SBC: Agouron Pharmaceuticals Inc.            Topic: N/A

    THE ULTIMATE OBJECTIVE OF THIS PROJECT IS TO UTILIZE THE INFORMATION AVAILABLE IN THE THREE-DIMENSIONAL CRYSTAL STRUCTURE OF AN ENZYME IN THE RATIONAL DESIGN OF DRUGS WHICHWILL BE EFFECTIVE AGAINST PLASMODIUM FALCIPARUM. THE SPECIFIC ENZYME TARGET IS THE BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE (DHFR-TS) OF P. FALCIPARUM. THE ACHIEVEMENT OF THIS GOAL WILL INVOLVE A CONCERTED EFFOR ...

    SBIR Phase II 1989 Department of Health and Human Services
  10. Composite Metal/Ceramic Bearings for THA Implants

    SBC: SINTX Technologies, Inc.            Topic: N/A

    DESCRIPTION (Provided by Applicant): The implications of developing materials with enhanced fracture toughness, damage resistance, reliability and ultra low wear is of significant interest to the orthopedic community, since it directly addresses a vital clinical concern- eliminating wear debris mediated THA implant failures. In Phase I we made a significant ...

    SBIR Phase II 2001 Department of Health and Human ServicesNational Institutes of Health
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