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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Structure-based discovery of dopamine D1 receptor selective small molecule ligands
SBC: CONFOMETRX, INC. Topic: 101Dopamine receptors are a family of G protein-coupled receptors (GPCRs), and can be further divided into D1-like (D1 and D5) and D2-like (D2, D3 and D4) subfamilies. In this proposal, we focus on D1 receptor, which is widely expressed in brain at high levels. Modulation of D1 activity is implicated in the treatment of many psychiatric and neurological disorders, such as schizophrenia, attention def ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Rapid and Simple Paper Strip Test for the Multiplexed Detection of Gastrointestinal Pathogens at the Point-of-Need
SBC: Godx Inc. Topic: 950PROJECT SUMMARY GoDx, Inc. has been developing a prototype multiplexed paper strip device for the detection of the DNA and RNA of gastrointestinal pathogens at the point-of-need in andlt; 30 minutes with funding from the NCATS SBIR parent grant TR 001912. We have used the same platform technology we are developing in the parent grant to develop a rapid (andlt;30 minute), low-cost and instrument-fr ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Development of a Functional Balloon-borne GNSS-RO System Prototype
SBC: Night Crew Labs, LLC Topic: 811The SBIR Phase II proposal outlines the approach of Night Crew Labs (NCL) in designing, and developing, and testing a system prototype to perform Global Navigation Satellite System radio occultations (GNSS-ROs) from a high-altitude balloon platform. NCL will continue building from the positive results achieved in Phase I that successfully demonstrated the feasibility of performing balloon-borne GN ...
SBIR Phase II 2019 Department of CommerceNational Oceanic and Atmospheric Administration -
Sea Tag-SP: A family of acoustic enabled satellite tags for spawning detection and more
SBC: DESERT STAR SYSTEMS, LLC Topic: 812Phase-1 demonstrated the powerful and unusual remote sensing opportunities available by adding acoustic signal detection to pop-up satellite tags (PSAT). The time and location of spawning define the starting point in the life history of fish. Yet this event, which is of critical importance to fishery researchers and managers seeking to gain an understanding of distinct reproductive populations and ...
SBIR Phase II 2019 Department of CommerceNational Oceanic and Atmospheric Administration -
Low-cost Mooring Location Beacon for Coastal Applications
SBC: TOYON RESEARCH CORPORATION Topic: 825Subsurface mooring beacons are used to provide notifications and assist in locating moored assets that have surfaced and are free drifting. Their nominal design is driven by the requirements for offshore use where they need to survive extreme depths and remote deployment, most often using satellite constellations for communication and geo-location. Existing beacons serve their purpose well, but th ...
SBIR Phase II 2019 Department of CommerceNational Oceanic and Atmospheric Administration -
Fog Viewer
SBC: Arete Associates Topic: 826The presence of fog reduces visibility, contributing to unsafe conditions for many maritime tasks. The current system uses active backscatter and has high power requirements, high maintenance and replacement costs. Areté Associates’ innovative FogViewer system comprises a passive multi-spectral, multi-polarization sensor suite that leverages available degrees of freedom to best characterize the ...
SBIR Phase II 2019 Department of CommerceNational Oceanic and Atmospheric Administration -
Rapid diagnostic to determine CMV serological status
SBC: NANOCOMPOSIX, INC. Topic: NIAIDThe goal of this project is to develop a diagnostic that can support the enrollment of seronegative individuals in clinical trials of candidate cytomegalovirusCMVvaccinesCongenital CMV infection is one of the leading causes of non genetic birth defects worldwideIf a successful vaccine can be brought to marketit will have a significant impact on the number of babies born with hearing and vision los ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
TOPIC 359: A DEVICE PROTOTYPE FOR ISOLATION OF MELANOMA EXOSOMES FOR DIAGNOSTICS AND TREATMENT MONITORING
SBC: Aethlon Medical, Inc. Topic: NCIThe proposed work aims to develop a pre commercial prototype of an exosome isolation device to be used in clinical diagnostic laboratoriesWe will advance the device to facilitate exosome isolation for downstream liquid biopsy tests requiring analysis of proteinDNAor microRNAwhich rely upon acquisition of intact and pure exosomesThe device strategy will be designed to isolate total exosomes and the ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
TOPIC 360: A SIMPLE END-TO-END SYSTEM FOR SERIAL CELL SORTING AND MANIPULATION USING A SINGLE CONTAINER- MOONSHOT
SBC: DIAGNOLOGIX, LLC Topic: NCIChemotherapy may control but rarely cure metastatic cancersRemarkablymodern immunotherapiesincluding cell based therapieshave cured metastatic melanomas and other types of cancersA major challenge for all cell therapies in general is the need to develop cost effective and efficient manufacturing and delivery capabilitiesWe have recently established an innovative cell isolation technology by applyi ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
TOPIC 353: HIGHLY ACCURATE LOW COST CTDNA DIAGNOSTICS WITH MAGNETIC NANOPARTICLE ENABLED AUTOMATED SAMPLE PREP- MOONSHOT
SBC: NVIGEN Topic: NCIThe goal of the research is to develop a highly accurateautomatedand low cost ctDNA test to monitor efficacy of treatment of metastatic breast cancer patients by identifying the emergence of certain DNA mutations in plasma samplesThere is growing evidence that the presence of certain DNA mutations in the blood stream correlates with breast cancer becoming resistance to hormone treatmentNVIGEN will ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health