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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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An Automated Early Motor Development Risk Screener from Observational Video Recordings of Infants and Toddlers
SBC: BSOLUTIONS, INC. Topic: NICHDMotor development plays a pivotal role in an infant’s overall development and has a cascading effect on social, cognitive, memory, and language ability. These functions can be compromised when motor development is disrupted; motor disruption is associated with generalized developmental delays. Early screening and identification of delays can allow early interventions with the goal of not just im ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
A Phase 1 Clinical Trial Evaluating the Novel Small Molecule Immuno-Oncology Antagonist SX-682 Alone and With Pembrolizumab in Metastatic Melanoma
SBC: Syntrix Biosystems, Inc. Topic: 102The chemokine receptors CXCR1 and CXCR2 (CXCR1/2) are validated as having essential roles in the growth, survival, motility, invasion and angiogenesis of human melanoma, which secretes abundant amounts of the corresponding chemokine ligands, including CXCL8. Additionally, abnormal cancer-induced immunosuppressive myeloid-derived suppressor cells (MDSCs) in the circulation and tumor correlate with ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Optimization and Validation of an indicator cell assay for blood-based diagnosis of lung cancer
SBC: PRECYTE INC Topic: 102Project Summary. The Indicator Cell Assay Platform (iCAP) is an inexpensive blood-based assay that can be used for early detection of disease, disease stage stratification, prognosis and response to therapy for a variety of diseases. The iCAP uses cultured, standardized cells as biosensors, capitalizing on the ability of cells to respond to disease signals present in serum with exquisite sensitivi ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Mechanism underpinning synergy with combined treatment of MTI-101 and Dexamethasone in Multiple Myeloma
SBC: MODULATION THERAPEUTICS, INC. Topic: NCIABSTRACT Multiple myeloma (MM) is the second most common hematopoietic cancer and while survival rates have slowly increase in the last 10 years, the five-year survival is just over 50%. The high number of patients that become refractory to current therapies is the core reason for the low long-term survival. Therefore, there is a crucial need to develop unique drugs that are active in refractory a ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Lab-To-Marketplace: Commercialization of a stretchable microelectrode array
SBC: BMSEED LLC Topic: 101Project Summary/Abstract The proposed work is directed at the commercialization of BMSEEDandapos;s Micro-Electrode Array Stretching Stimulating und Recording Equipment (MEASSuRE) technology. MEASSuRE bridges the gap between in vitro and in vivo research by simulating the biomechanical and electrical environment of cells in the body in a controlled environment outside of the body. The applications ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Pdot-Enabled Point-of-Care Digital PCR for Sensitive Detection of SARS-CoV-2
SBC: LAMPROGEN INC Topic: 400Project Summary Current SARS-CoV-2 molecular diagnosis tests mostly are based on real-time quantitative PCR (qPCR). Digital PCR is a next-generation PCR technology based on limiting dilution, end-point PCR, and Poisson statistics. Digital PCR transforms the exponential, analog nature of qPCR quantification into a linear, digital signal quantification. Compared to qPCR, digital PCR offers several i ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Enhanced Recovery of Pharmaceutical Solvent driven by EPA Initiative
SBC: COMPACT MEMBRANE SYSTEMS, INC. Topic: NIEHSSummary Enhanced Recovery of Pharmaceutical Solvent driven by EPA InitiativeThe United States Environmental Protection AgencyEPAis establishing new safeguards for hazardous secondary materials with objectives to promote the economicenvironmentaland public health benefits of recycling wasteswith an emphasis on several industrial sectorsincluding the pharmaceutical industryOn averagepharmaceutical m ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Novel Methodology for Identification of Senolytics that Reduce Age-related Disease and Dysfunction
SBC: Recursion Pharmaceuticals, LLC Topic: NIADESCRIPTION (provided by applicant): Chronic diseases of aging account for a significant proportion of healthcare spending and result in a painful and limiting existence for many tens of millions of Americans and hundreds of millions of people around the world. Recursion Pharmaceuticals has developed a drug discovery platform that re-purposes known drugs for the treatment of such diseases. The pla ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Optimization and Validation of an Indicator Cell Assay for Blood-Based Diagnosis of Alzheimer's Disease
SBC: PRECYTE INC Topic: NIAProject Summary. PreCyte is developing the Indicator Cell Assay Platform (iCAP) as a broadly applicable and inexpensive blood-based assay that can be used for the early detection of disease, disease stage stratification, prognosis and predicting response to therapy for a variety of diseases. The iCAP uses cultured, standardized cells as biosensors, capitalizing on the ability of cells to respond t ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
IOBIO based, distributed genomic data access, management, visualization, and analysis
SBC: FRAMESHIFT LABS INC Topic: 172The precision medicine initiative coupled with advances in genomic research and diagnostics isleading to vast increases in the volume of genomic data being createdwith some estimates statingit will outstrip the storage requirements of YouTube byEnsuring all this data can becost effectively managedand that experts from the biomedicalinformatics and medical disciplinescan easily collaborate on analy ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health