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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. RESEARCH WILL BE CONDUCTED INTO OPTICAL FIBER-COUPLED FLUORESCENT SENSORS FOR THE CONTINUOUS IN VIVO MONITORING OF BLOOD GASES.

    SBC: Abel Company            Topic: N/A

    RESEARCH WILL BE CONDUCTED INTO OPTICAL FIBER-COUPLED FLUORESCENT SENSORS FOR THE CONTINUOUS IN VIVO MONITORING OF BLOOD GASES. THE PURPOSE OF PHASE I IS TO IDENTIFY FLUORESCENT CHEMICAL SYSTEMS SPECIFICALLY SENSITIVE TO PH, PO2, PCO2, AND TEMPERATURE. FROM THESE IDENTIFIED SYSTEMS, A SELECTION WILL BE MADE OF THOSE COMPATIBLE FOR USE IN A MIXED SENSOR PROBE. THE GOAL OF THIS STUDY IS TO MINIMIZE ...

    SBIR Phase I 1984 Department of Health and Human Services
  2. In vivo Testing of S. aureus alpha-Hemolysin Inhibitors

    SBC: Innovative Biologics Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): We have recently demonstrated that alpha-hemolysin produced by S. aureus plays a key role in the pathogenesis of staphylococcal pneumonia, and identified beta-cyclodextrin derivatives that potently inhibit the cytotoxic effects of this secreted bacterial toxin. The overall goal of this feasibility study is to examine the ability of these inhibitors to provide i ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  3. Non-Intrusive Automated Portable Data Collection System for Aging Surveys

    SBC: AFrame Digital, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The Cells and Surveys report (National Research Council 2000) reports that collecting biological information dramatically improves the value of household surveys by adding a rich dataset of information to longitudinal databases that is not collected today. In fact, since the Cells and Surveys report the collection of biological data and performance measures (in ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  4. THE PRIMARY OBJECTIVE OF THE PROPOSED PROGRAM IS THE ULTIMATE DEVELOPMENT OF A PRACTICAL WEARABLE AIR POWER SUPPLY FOR AN IMPLANTED PNEUMATIC ARTIFICIAL HEART.

    SBC: Amnis Corporation            Topic: N/A

    THE PRIMARY OBJECTIVE OF THE PROPOSED PROGRAM IS THE ULTIMATE DEVELOPMENT OF A PRACTICAL WEARABLE AIR POWER SUPPLY FOR AN IMPLANTED PNEUMATIC ARTIFICIAL HEART. THE PROPOSAL ADDRESSES ITSELF TO THE CONCEPT OF A WEARABLE POWER SUPPLY FOR A PNEUMATIC HEART THAT HAS BEEN IMPLANTED IN AN AMBULATORY PATIENT, AND SEEKS TO IDENTIFY THE SMALLEST AND LIGHTEST PNEUMATIC DRIVE FOR THE APPLICATION, SO THAT A U ...

    SBIR Phase I 1984 Department of Health and Human Services
  5. WEARABLE, NON-GRAVITY-DEPENDENT INFUSION DEVICE

    SBC: Amnis Corporation            Topic: N/A

    N/A

    SBIR Phase I 1984 Department of Health and Human Services
  6. WEARABLE RESPIRATOR

    SBC: Amnis Corporation            Topic: N/A

    N/A

    SBIR Phase I 1984 Department of Health and Human Services
  7. Vascular Targeting for Imaging and Treatment of Benign Prostatic Hyperplasia

    SBC: ANDROBIOSYS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Benign Prostatic Hyperplasia/Hypertrophy is a major health problem in the United States, with one-in-three men having urologic problems. Currently available treatment modalities include alpha-blockers that do not affect the underlying pathologic process, and 5-alpha-reductase inhibitors that have significant systemic side-effects. We have discovered that human ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  8. Primary Xenografts of Human Tissue as Surrogates of Cancer In Situ

    SBC: ANDROBIOSYS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): AndroBioSys, Inc. is dedicated to the development of human tissue-based in vivo tools capable of selecting better targeted agents for clinical trials by improved preclinical testing. AndroBioSys has developed the technology for reproducible implantation of primary xenografts of benign and malignant human prostate and kidney tissue. Xenografts have been establis ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  9. Novel therapeutic for Alcoholic Liver Disease

    SBC: Angion Biomedica Corp.            Topic: N/A

    DESCRIPTION (provided by applicant): Alcoholic Liver Disease (ALD) is a progressive liver disease that in advanced stages can result in cirrhosis and liver failure. ALD can be divided in various stages of development: (1) mild alcoholic liver injury, (2) steatosis, (3) alcoholic hepatitis, (4) alcoholic liver fibrosis and (5) cirrhosis. Liver fibrosis is a form of scar formation that is found in a ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  10. Phase I Study of BB3 in Dialysis Patients

    SBC: Angion Biomedica Corp.            Topic: N/A

    DESCRIPTION (provided by applicant): Kidney transplantation is the most effective therapeutic modality for end-stage renal disease; it offers a better quality of life and a longer survival. Despite improvements in surgical and organ preservation techniques over the last decade, renal dysfunction and/or failure remains a significant problem following transplantation. Ischemia-reperfusion injury ass ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
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