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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Supine Breast MRI Standardization for Breast Cancer Locator
SBC: CAIRNSURGICAL, INC. Topic: 102PROJECT SUMMARY/ABSTRACT:CairnSurgical, Inc., a Dartmouth spin-off company, will standardize supine breast MRI to streamline pro- duction of the Breast Cancer Locator (BCL) as a cancer localization device for use in breast conserving surgery (BCS) to (i) eliminate wire localization – a moderately effective, somewhat costly and certainly inconvenient procedure for patients and surgeons – and co ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
PHS 2018-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Gra
SBC: CREARE LLC Topic: NCIPCPROJECT SUMMARY/ABSTRACT Creare and its clinical and research partners propose to develop a software platform, OnTRACK (Online Treatment Recovery Assistance for Concussion in Kids), for children and adolescents recovering from concussion or mild traumatic brain injury (mTBI). The platform includes a mobile application (app) for the patients and their care team (parents, teachers, coaches, etc.), a ...
SBIR Phase II 2019 Department of Health and Human ServicesCenters for Disease Control and Prevention -
Single-cell Phosphoprotein Assay to Evaluate Brain Tumor Therapeutic Resistance
SBC: ISOPLEXIS CORPORATION Topic: 102Although signal transduction inhibitors occasionally offer clinical benefit for cancer patients, signal flux emanating from oncogenes is often distributed through multiple pathways, potentially underlying the resistance which causes failure of most such inhibitors. Measuring signal flux through multiple pathways, in response to signal transduction inhibitors, may help uncover network inter- action ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
A badge-like exposure device for occupational safety and epidemiological study
SBC: TF HEALTH CORPORATION Topic: RAbstract Chemical exposure poses a threat to the safety and health of each of us, especially those who work in certain industries, such as petroleum extraction and refinery facilities, mining industry, and fertilizer factories. Various sensing technologies have been developed over the past decades to address the need, but a low cost and accurate personal exposure device that can track multiple che ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Cellular Immunotherapy for Systemic Sclerosis
SBC: CELDARA MEDICAL, LLC Topic: NIAMSProject Summary Systemic sclerosis (SSc) is a systemic autoimmune disease that results in widespread fibrosis of the skin and internal organs, vascular dropout and autoantibody formation. SSc has the highest case fatality rate of any systemic autoimmune disease and there remain no FDA-approved therapies. Our data and that of others indicate that the innate immune system is the major driver of fibr ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
A Compact Turbo-Rankin Energy Conversion System
SBC: CREARE LLC Topic: 8211Creare is developing a miniature power system for NOA weather monitoring stations in remote locations. This system can provide electric power continuously from naturally occurring temperature differences that exist between ambient air and water in environments such as the Arctic Ocean and the Great Lakes. Generating power directly from these temperature difference uses the atmosphere and ocean/lat ...
SBIR Phase II 2019 Department of CommerceNational Oceanic and Atmospheric Administration -
A Single-Cell Proteomic instrument for Predictive Product Quality Check in Autologous CAR-T Immunotherapies
SBC: ISOPLEXIS CORPORATION Topic: 102While CAR-T therapies have advanced in the clinic, there are still two specific issues using these breakthrough therapies for blood cancers: Durable responses in patients are only at 30-50% and Cytokine Release Syndrome occurs in 60-90% of treated patients. These limitations, for a drug that costs as much as $500,000, may cost an additional $250,000+ for treating adverse events leading to caution ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
A Non-Contact Optical Patient and Beam Dosimetry System for Continuous in vivo Radiotherapy Verification
SBC: DOSEOPTICS LLC Topic: 102Abstract Optical Cherenkov video imaging of body anatomy and dose delivery can be used now to map out radiotherapy beam incidence upon the patient tissue, directly visualizing the radiation dose deposition on the patient in real time. This could serve as a non-contact workflow tool for verification for daily fractionated radiation therapy, allowing capture of all treatments, all the time. DoseOpti ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Sustained release gel enabling one-stage treatment of prosthetic joint infection
SBC: SONORAN BIOSCIENCES INC Topic: NIAIDProsthetic joint infections (PJIs) are a serious complication of total joint replacement surgery. PJIs accounted for about $6 billion in healthcare costs in 2018. Unfortunately, treatment of PJI is under-reimbursed, and healthcare reforms are putting increasing economic pressure on hospitals to bear the high costs of treating these infections. New technologies are badly needed to improve the quali ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Multi-Omic Single-Cell System for Improved Combination Cancer Immunotherapy Monitoring and Implementation
SBC: ISOPLEXIS CORPORATION Topic: 102IsoPlexis proposes to deliver a novel multi-omic method for targeted profiling of both the TCR sequence and proteome from an array of 1000+ single cells. Specifically, we will deliver a single-cell, TCR sequencing and protein capture assay for identifying responsive antigen specific TCRs, and concurrently evaluate these T-cells for functional response to that antigen. The challenge remains to link ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health