Award Data

DESCRIPTION (provided by applicant): Epoch Telemetry System for Long-Term Monitoring of Biopotentials ABSTRACT Neonatal and childhood seizures can increase an individual's susceptibility for developing epilepsy later in life. Obtaining long-term continuous recordings of electrical events, such as the electroencephalogram (EEG), from animal models of neurological disease is a critical comp ...

Oscilla Power, Inc. (OPI) is developing a utility-scale wave energy harvester that is enabled by low cost and readily-available magnetostrictive alloys. T his device, which utilizes no moving parts, has the potential to deliver predictable quantities of electric power to coastal utilities, industrial users, and remote facilities at costs competitive with coal or gas. The Phase I project demonstra ...

Marine aquaculture production now exceeds 20 million metric tons annually (FAO 2010) but viral diseases are still a major threat to the expansion of sustainable mariculture systems (National Marine Fisheries Service 2007). Pathogenic viruses continue to devastate many fish and shellfish operations every year (ICES Mariculture Committee 2004, Lightner 2011). To date, vaccines against aquatic anim ...

Extremely Efficient Nebulizer for Intranasal Vaccination. Specifically the nasal delivery device could reduce health care associated infections by providing a needle-free method of delivery of vaccines and therapeutics which are currently delivered by injection with all the attendant risks of transmission of blood borne disease through needle-stick injury and unsafe needle practices. One of the m ...

DESCRIPTION (Provided by Applicant): The implications of developing materials with enhanced fracture toughness, damage resistance, reliability and ultra low wear is of significant interest to the orthopedic community, since it directly addresses a vital clinical concern- eliminating wear debris mediated THA implant failures. In Phase I we made a significant ...

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DESCRIPTION: The efficacy and safety of photodynamic therapy (PDT) depends on an understanding of photosensitizer and light biology and dosimetry. Therefore, the ability to accurately determine photosensitizer levels in tumors and at-risk normal tissues is of utmost importance. The goal of this work is to develop and test a prototype system for fluorescence based m ...

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DESCRIPTION (provided by applicant): Persons with severe and persistent mental illness (SPMI) commonly experience both Substance Use Disorders (SUDs) and Borderline Personality Disorder (BPD), resulting in serious and complex personal costs and public heal th problems. Although Assertive Community Treatment (ACT) is efficacious for persons with SPMI, it is less clear the extent to which this appro ...