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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 1 - 10 of 6092 results
  1. A Phase 2, Single-Arm Study of the CXCR1/2 Inhibitor SX-682 Plus Enzalutamide in Men with Abiraterone-Resistant Metastatic Castration Resistant Prostate Cancer (mCRPC)

    SBC: Syntrix Biosystems, Inc.            Topic: 102

    Prostate cancer (PC) is the second leading cause of cancer-related death among American men, and the vast majority of these deaths are due to metastatic, castration-resistant PC (mCRPC). Androgen suppression therapy (AST) is used to treat PC patients, which comprise of: (1) androgen deprivation therapy (ADT) with LHRH agonists or antagonists; (2) blocking CYP17-mediated androgen synthesis with abi ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  2. Home Monitoring of Metabolic Disorders

    SBC: SEQUITUR HEALTH CORP            Topic: NICHD

    PROJECT SUMMARY This proposal is submitted in direct response to NOT-HD-22-009 Notice of Special Interest (NOSI): Innovative Technologies to Improve Assessments, Interventions, and Outcomes for Individuals with Intellectual and Developmental Disabilities [IDD] (R43/R44). Persons of all ages with certain metabolic disorders are at-risk for metabolic crises when a certain metabolite accumulates, whi ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  3. Clinic-Ready MACH-1 Gene Gun for delivery of a universal influenza DNA vaccine

    SBC: ORLANCE, INC            Topic: NIAID

    PROJECT SUMMARY Orlance has developed a lead universal influenza (UFlu) DNA vaccine to address the need for a vaccine that can protect from annual influenza and the emergence of new variants that could cause future pandemics. Our UFlu vaccine is a multi-dose vaccine designed to induce systemic and mucosal immune responses that can prevent transmission and minimize disease from currently circulatin ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  4. Development of a Universal Assay for Minimal Residual Disease in Acute Myeloid Leukemia using Duplex Sequencing

    SBC: TWINSTRAND BIOSCIENCES INC            Topic: NCI

    Problem: With a 5-year survival of ~30%, AML is the 6th deadliest cancer, and rt20,000 new patients are diagnosed each year in the United States. Although most patients achieve Complete Remission (CR) with aggressive therapy, most will eventually relapse. The criteria for CR, however, is based on historical diagnostic methods, and patients in CR may carry up to 1010 residual leukemia blasts. Signi ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  5. Dodecafluoropentane emulsion (DDFPe), NanO2™ as Cerebroprotectant in Ischemic Stroke

    SBC: NUVOX PHARMA, L.L.C.            Topic: NINDS

    ABSTRACT / PROJECT SUMMARY Stroke affects more than 795,000 patients per year in the US and kills approximately 40,000. Long-term medical care expense for stroke in the US, costs over $34B per year. Large vessel occlusion (LVO) stroke accounts for almost 40% of ischemic strokes but causes 95% of mortality and 62% of long-term dependence. Mechanical thrombectomy (MT), or a combination of MT and tPA ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  6. On-Site Destruction of PFAS-Impacted Liquids

    SBC: Aquagga, Inc.            Topic: AF211CSO1

    Per- and polyfluoroalkyl substances (PFAS) have been used extensively for DoD firefighting applications due to their thermochemical stability and unique properties. PFAS are recalcitrant environmental pollutants and bioaccumulative toxins, presenting DoD installations with significant environmental compliance and remediation challenges. The most significant PFAS issues are a direct result of aqueo ...

    SBIR Phase II 2023 Department of DefenseDefense Advanced Research Projects Agency
  7. Scalable MXene Synthesis for Aerospace Applications

    SBC: BALLYDEL TECHNOLOGIES INC.            Topic: AF21ATCSO2

    During the Phase II effort, Ballydel Technologies will develop scalable and safe processes for the manufacture of MAX phase and MXene powders in 1Kg batch sizes.  Additionally, our team will implement commercial-scale mixing procedures for the production

    STTR Phase II 2023 Department of DefenseAir Force
  8. A Prototype for Geosynchronous Satellite Surveillance using Passive RF Collection

    SBC: RINCON RESEARCH CORPORATION            Topic: SF224D007

    As is well noted, GEODSS telescopes are unable to perform their primary space surveillance mission during daytime and weather outages. Passive RF provides a needed augmentation to the GEODSS mission with its ability to maintain custody and support routine

    SBIR Phase II 2023 Department of DefenseAir Force
  9. Position, Navigation and Timing (PNT) Without the Global Positioning System (GPS)

    SBC: Namatad Inc            Topic: A19CT003

    Deployed military personnel are required to navigate, assess, and mitigate threats within complex, unknown structures located in hostile environments where access to satellite-transmitted GPS-based positioning signals may be limited, unavailable, or intentionally denied. The lack of accurate, real-time location data impacts mission-level situational awareness, particularly for operations that requ ...

    STTR Phase II 2023 Department of DefenseArmy
  10. DIALR Phase II

    SBC: PRIME SOLUTIONS GROUP, INCORPORATED            Topic: OSD221002

    The pace of remotely sensed data collection is increasing exponentially while the skilled workforce that is available to analyze and interpret the data is not. Artificial Intelligence (AI) offers a technology pathway to automation which promises to rapidly reduce the gap between data and information products and services. However, AI techniques require massive quantities of labeled data to train m ...

    SBIR Phase II 2023 Department of DefenseNational Geospatial-Intelligence Agency
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