Award Data

We propose to develop an innovative concept of the high speed dynamic IRSP that combines components and devices from proven suppliers with novel system-level research topics from CDS and University of Delaware. Having previously built and delivered working LED IRSPs to users gives CDS a unique advantage. In line with system theme of the solicitation, our phase 1 research topics are focused on syst ...

Abstract The primary liver cancer including intrahepatic bile duct cancer pose significant global burden of illness with increasing incidence and mortality in US and around the world. Surgery remains the most effective form of treatment. However, surgical complication rates for medium to high complexity hepatectomies persist in 30-40% range even in highly skilled hands and at high volume centers. ...

DESCRIPTION provided by applicant Kinase inhibitors created a new paradigm in chemotherapy and are a major focus of new oncology drug development The Bcr Abl inhibitor imatinib was a breakthrough drug for chronic myelogenous leukemia with overwhelming early results however at least of patients are either intolerant resistant or experience recurrence within years and individual respo ...

Many large-scale numerical simulations can be broken down into common mathematical routines. While the applications may differ, they often need to perform standard functions such as system solves, Fourier transforms, or eigenvalue calculations. Consequently, producing fast, efficient implementations of these methods will benefit a broad range of Air Force applications. Graphics Processing Units (G ...

ABSTRACT: High-performance computing (HPC) programmers and domain experts, such as those in the Air Force's research divisions, develop solvers for a wide variety of application areas such as modeling next generation aircraft and weapons designs and advanced image processing analysis. When developing software for HPC systems, the programmer should not spend the majority of their time optimiz ...

UAVS (Unmanned Aircraft Vehicle System) integration with naval vessels is currently realized in limited form. This is largely due to the fact that the operational envelopes of these vehicles are based solely on at-sea flight testing. In addition to the complexities involved with at-sea flight testing, the unsteady nature of ship-airwakes and the use of automated UAV control software necessitates ...

DESCRIPTION (provided by applicant): A significant problem currently hindering proteomics studies is the identification of peptides and proteins from mass spectral data. This problem is manifest in the difficulty to establish confidence limits of protein a nd peptide identifications. A serious concern is the tendency for the occurrence of false positive assignments. The development of an integrate ...

Adiabatic reversible logic provides a way to dramatically reduce power dissipation by recovering the energy used to encode information, rather than dissipating the energy to heat, as is done in conventional CMOS. For Phase I we will design test circuits that will evaluate the energy savings in adiabatic reversible logic, as compared to conventional logic. In addition to these smaller circuits, a M ...

Indiana Integrated Circuits, LLC (IIC) and the University of Notre Dame, proposes to design, fabrication, and test/verification of an adiabatic reversible-logic microprocessor, building upon a very productive Phase I. The Phase I effort saw the successful design and verification of a 16-bit MIPS microprocessor using adiabatic logic in 90 nm CMOS. Simulations performed as part of the completed Phas ...

The objective of this proposal is to research, develop and characterize Composite materials with the ability to increase blast and fragment protection. In Phase I, CAE-net will conduct research into an integrated network of visco-elastic dampers and stiffeners constructed of materials suitable for use in the environmental, geometric and blast/fragment conditions. CAE-net will develop a methodology ...