Award Data

Autonomous inspection systems are necessary to increase awareness of track safety and maintenance issues. However, electrical power for these systems is not available under freight railway vehicles. Mainstream Engineering (MEC) proposes development of a small-scale diesel generator with an integrated starter-alternator (ISA) and automated battery charging circuit for this application. The proposed ...

In the proposed effort, we will leverage this extensive experience and capabilities to realize a frequency agile mmW radiometer that can cover the range of DC-110 GHz and can be scaled to DC-200 GHz under Phase II. Ours is a photonic system that multiplies and up-coverts a low-frequency reference signal onto an optical carrier (laser) using EO modulation, then uses the modulation sidebands to inj ...

DESCRIPTION (provided by applicant): Multiple Sclerosis (MS) is an autoimmune disease that affects the central nervous system (CNS) and results in neurological and clinical disability i number of adults in the US. Leukocyte infiltration and plaques of demyelination in the brain and spinal cord of patients are a hallmark of MS. Currently, there is no cure and few therapies for this debilitating ...

DESCRIPTION (provided by applicant): Lung cancer is the leading cause of cancer deaths worldwide. The high mortality is in part due to the lack of good tests for early detection and treatment. Our technology diagnoses the presence of cancer via analysis ofthe specific fingerprint of volatile organic molecules produced by tumor metabolism, out- gassed from tumor tissue to blood and excreted in urin ...

DESCRIPTION (provided by applicant): The majority of multiple myeloma (MM) patients will initially respond to standard chemotherapy. However, eventually relapse of the disease, associated with a multi-drug resistant phenotype, contributes to poor clinicaloutcomes. Modulation Therapeutics is dedicated towards developing strategies for targeting cancers like MM that home or metastasize to the bone. ...

DESCRIPTION (provided by applicant): This project aims to develop a device capable of acquiring transient and steady state auditory evoked potenlatials (AEPs) simultaneously using an efficient and advanced processing technique. The proposed technique willbe implemented as a software module on Intelligent Hearing Systems' (IHS) evoked potential system platform. Auditory Transient Responses (AT ...

DESCRIPTION (provided by applicant): Type 1 Diabetes (T1D) is thought to result from a breakdown of self-tolerance that is characterized by T cell-mediated destruction of the insulin-producing -cells in the pancreas. Ultimately, glucose metabolism is interrupted, resulting in the development of life-threatening complications such as heart disease and renal failure. A number of factors are known t ...

DESCRIPTION (provided by applicant): Acute pesticide poisoning remains a vast health problem in the developed and developing world. Domestically, a 2004 study estimates that 18 of every 100,000 US agricultural workers suffer from acute pesticide poisoningand a 2002 study of California air found dangerous levels of three pesticides in urban areas. Since pesticides are primarily applied by sprayers ...

DESCRIPTION: Enhanced Membrane System for Supplying Quality Drinking Water Contaminants in Drinking Water: While many of the traditional waterborne diseases (cholera, typhoid) are now uncommon in the developed world, the continue to be a major cause of disease in developing countries and waterborne disease kills more people worldwide than all forms of violence. Waterborne disease outbreaks contin ...

DESCRIPTION: An estimated 2.5 billion people, or about one-third of the world's population, rely on biomass fuel for cooking. Emissions from biomass cook stoves contribute to global climate change, indoor/local air quality issues, and related health effects. In particular, indoor ir quality issues related to biomass cook stoves contribute significantly to rates of acute respiratory infection ...