Award Data

Recent foodborne illness outbreaks traced to contaminated field harvesting equipment have highlighted the need for incorporating improved sanitization practices at the time of harvest. Field- harvested specialty crops represent 50% of the top ten foods linked to major recalls and outbreaks over the past five years. Proper sanitization of outdoor harvest equipment is made complicated by operational ...

ABSTRACT This project is the development of a non-invasively extending distal femur replacement (DFR) for children and adolescents subsequent to bone tumor resection. Each year in the US there are 200-250 malignant bone tumor diagnoses in the distal femurs of patients 15 years and younger. With advances in chemotherapy, limb salvage surgery utilizing a megaprosthesis has increasingly become the tr ...

Attollo Engineering proposes to address the need for a quick-draw, pouch-storable laser rangefinder for day and night urban use. This self-contained unit will weigh less than 18 ounces and have a total volume less than 64 cubic inches. The system will provide post-fire target assurance, showing the operator where the laser landed on the target. In Phase I Attollo will survey and evaluate all relev ...

Tactical Navy HTS magnet applications require efficient and compact cryocoolers to maintain cryogenic temperatures for the magnet while also accommodating the physical and environmental constraints within the HTS magnet system. Currently available commercial-off-the-shelf (COTS) cryocoolers fall short on achieving the cryogenic cooling requirements that are needed for future tactical HTS magnets. ...

PROJECT SUMMARY/ABSTRACT Clinical Need: The coming decades promise a revolution in the personalized treatment for patients with breast cancer, including approaches to minimize collateral damage of curative. However, to help facilitate this, the academic and industrial clinical research communities need improved diagnostic biomarkers to assess the presence of muscle diseases such as sarcopenia. Onc ...

Project Summary Acute ischemic stroke (AIS) impacts 795,000 Americans per year, leaving 90% of patients with chronic disability. Prevalent cases of AIS in the US were estimated at 6.7M in 2017, translating to 6M Americans living with permanent stroke-related disability. AIS is characterized by cerebrovascular blockage that results in the formation of a central infarct with a surrounding ischemic p ...

7. Project Summary/Abstract Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease in North America (1). Hepatic steatosis (HS) is the hallmark of NAFLD (2). NAFLD may transition in sub-groups to chronic inflammation (non- alcoholic steatohepatitis, NASH), and ultimately to cirrhosis. HS is prevalent in all stages of NAFLD. 3-10% of all children in the US and 40-70% of obese ch ...

SUMMARY Amyotrophic lateral sclerosis (ALS) patients develop fatal paralysis as a result of progressive motor neuron loss in the brain and spinal cord. There are more than 5,000 new cases of ALS per year in the United States, with typical age of onset between 40 and 70 years of age. While SOD1 is a cytoplasmic protein, misfolded SOD1 can be secreted and form extracellular oligomers and aggregates. ...

The DLA has a need to identify competent and qualified domestic suppliers for mission-critical items that are becoming increasingly scarce. To combat the obsolescence issue, Mentis Sciences Inc. (Mentis) proposes a qualification effort for Bleed Air Ducting for the C-5 Galaxy Air Vehicle (C-5). Mentis understands the importance of supporting the C-5 and maintaining a strong supply chain for compon ...

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