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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Enhancing Biosynthesis of Biofuels from Cellulosic Biomass (Topic 8.8)

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: 88

    This program will provide low cost routes for biosynthesis of these and many other organics. Using biomass for production of fuels and chemical provides for a domestic, renewable and green route to address our fuel and chemical needs. This program provides a simple and inexpensive route for generating these domestic and renewable products

    SBIR Phase I 2010 Department of Agriculture
  2. Pelleted sericea lespedeza diet for control of internal parasites and pathogens in goats and sheep

    SBC: SIMS BROTHERS INCORPORATED            Topic: 83

    Internal parasites are the greatest health and production challenge for sheep and goats in southeastern states and others during warm, humid conditions (including Northeastern, Midwestern and irrigated pastures in Western US). Haemonchus contortus or barber pole worm thrives in warm, humid climates and is a voracious blood feeder that can cause anemia and death to the animal if left untreated. Dew ...

    SBIR Phase I 2010 Department of Agriculture
  3. Nucleic acid delivery of growth factors and heparan sulfate proteoglycans for enh

    SBC: International Medicine and Biomedical Research            Topic: NIAMS

    DESCRIPTION (provided by applicant): In chronic wounds, numerous factors contribute to the diminished healing. Wound healing constituents, including heparan sulfate proteoglycans and numerous growth factors, are essential to normal skin wound healing. Several key growth factors such as FGF, VEGF, and PDGF require heparan sulfate-like polymers as co- receptors or co-activators for growth factor act ...

    SBIR Phase I 2010 Department of Health and Human Services
  4. EpiMapVis: A dynamic web-based climate change and remote sensing visualization an

    SBC: APPLIED GEOSOLUTIONS LLC            Topic: NIEHS

    DESCRIPTION (provided by applicant): Many infectious diseases and chronic illnesses have underlying spatiotemporal relationships with the environment that are challenging to integrate into public health strategies. Compounding this challenge is the growing threat from climate change and lack of actionable information. Access to pertinent geospatial data, disparate data sources, and lack of data us ...

    SBIR Phase I 2010 Department of Health and Human Services
  5. Development of recombinant rhTL1A protein for cancer treatment

    SBC: BIOPOWERTECH            Topic: NCI

    DESCRIPTION (provided by applicant): Breast cancer is the most common cause of cancer in women and the second most common cause of cancer death in women in the United States. In 2009, approximately 40,170 women in the US are estimated to die from breast cancer. In most cases, death results from metastasis of breast cancer cells. Cancer patients with metastasis cannot currently be cured. Therefore, ...

    SBIR Phase I 2010 Department of Health and Human Services
  6. A Nanofluidic Nanoplasmonic Platform for Multiplexing Detection of Cancer Biomark

    SBC: CFD Research Corporation            Topic: NCI

    DESCRIPTION (provided by applicant): This project aims to develop a novel nanofluidic-nanoplasmonic platform to realize multiplexed monitoring of biological binding processes, specifically for detection of cancer biomarkers in bio-fluids. In contrast to current large-sized, cumbersome surface plasmon resonance (SPR) sensing technology, the proposed device is comprised of a multilayer nanostructure ...

    SBIR Phase I 2010 Department of Health and Human Services
  7. Surface Enhanced Biocompatible Blood Oxygenators

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: NHLBI

    DESCRIPTION (provided by applicant): Compact Membrane Systems, Inc. proposes to develop novel blood oxygenator membranes with enhanced blood biocompatibility. These will be used to enhance conventional cardio bypass surgery minimizing post operative effects. In addition, they will provide a key element for long term blood oxygenation associated with extracorporeal membrane oxygenation, acute respi ...

    SBIR Phase I 2010 Department of Health and Human Services
  8. Discovery of Inhibitors of PTH-Wnt Signaling Synergy in Bone Cells

    SBC: DISCOVERYBIOMED, INC.            Topic: NIAMS

    DESCRIPTION (provided by applicant): Project Summary Description Title: Discovery of Inhibitors of PTH-Wnt Signaling Synergy in Bone Cells. Osteoporosis is a growing problem in the aged and an unfortunately large disease market and burden to the healthcare industry. This debilitating disease costs 18 billion in healthcare costs annually in the US and affects 10 million people in the US and an est ...

    SBIR Phase I 2010 Department of Health and Human Services
  9. TCR-less Targeted T Cells Against Cancer

    SBC: CELDARA MEDICAL, LLC            Topic: NCI

    DESCRIPTION (provided by applicant): This year cancer will become the leading cause of death worldwide. The global burden of cancer doubled between 1975 and 2000. By 2020, it is projected to double again, and to triple by 2030. Ideally, any cancer therapy should be effective (at killing cancerous cells), targeted (i.e. selective, to avoid killing healthy cells), permanent (to avoid relapse and met ...

    SBIR Phase I 2010 Department of Health and Human Services
  10. ChNKG2D-Targeted Cellular Cancer Therapy: Preclinical Toxicology

    SBC: CELDARA MEDICAL, LLC            Topic: NHLBI

    DESCRIPTION (provided by applicant): Cancer is projected to become the leading cause of death worldwide by 2010. The global burden of cancer doubled between 1975 and 2000. By 2020, it is projected to double again, and to triple by 2030. Multiple myeloma (MM) is a particularly deadly type of cancer. In 2008, 19,920 Americans were diagnosed with MM, and 10,690 died. Five-year survival rates are on ...

    SBIR Phase I 2010 Department of Health and Human Services

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