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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Enhancing Biosynthesis of Biofuels from Cellulosic Biomass (Topic 8.8)

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: 88

    This program will provide low cost routes for biosynthesis of these and many other organics. Using biomass for production of fuels and chemical provides for a domestic, renewable and green route to address our fuel and chemical needs. This program provides a simple and inexpensive route for generating these domestic and renewable products

    SBIR Phase I 2010 Department of Agriculture
  2. Semiconductor Ultraviolet Irradiation Devices for Greenhouse Crops

    SBC: Sensor Electronic Technology, Inc.            Topic: 813

    We propose developing, manufacturing, fielding and validating environmentally friendly, energy efficient revolutionary ultraviolet irradiation devices (UID) to improve nutritional value of greenhouse crops. UIDs will be based on a new technology to produce deep ultraviolet semiconductor Light Emitting Diodes (DUV LEDs) with emission wavelengths below 300 nm. DUV LEDs can be designed and manufactur ...

    SBIR Phase I 2010 Department of Agriculture
  3. AlignShop: a comprehensive multiple sequence alignment editor and analysis tool

    SBC: AGILE GENOMICS, LLC            Topic: NIGMS

    DESCRIPTION (provided by applicant): Multiple sequence alignment (MSA) is a core element of bioinformatics, comparative genomics, phylogenetics, molecular, and structural biology. Several excellent software tools for MSA construction are heavily used by the biomedical community; however, essentially all automatically constructed MSAs require significant editing (error corrections) prior to their a ...

    SBIR Phase I 2010 Department of Health and Human Services
  4. EpiMapVis: A dynamic web-based climate change and remote sensing visualization an

    SBC: APPLIED GEOSOLUTIONS LLC            Topic: NIEHS

    DESCRIPTION (provided by applicant): Many infectious diseases and chronic illnesses have underlying spatiotemporal relationships with the environment that are challenging to integrate into public health strategies. Compounding this challenge is the growing threat from climate change and lack of actionable information. Access to pertinent geospatial data, disparate data sources, and lack of data us ...

    SBIR Phase I 2010 Department of Health and Human Services
  5. Assessment of MitoQ Therapy for Cold Preservation Renal Damage

    SBC: Cell & Tissue Systems, Inc.            Topic: NIDDK

    DESCRIPTION (provided by applicant): Renal transplantation has been a clinical reality for nearly 40 years. Transplantation is the only effective solution for organ end-stage renal failure. Long term renal function following transplantation has been shown to be better when kidneys are not subjected to cold preservation storage. However, despite the fact that cold preservation elicits significant k ...

    SBIR Phase I 2010 Department of Health and Human Services
  6. Cryopreservation of Human Epidermal Skin Models

    SBC: Cell & Tissue Systems, Inc.            Topic: NCRR

    DESCRIPTION (provided by applicant): In an effort to reduce the use of animals for toxicity testing, companies have developed in vitro skin models or equivalents to replace the Draize skin irritation test. This development has been further pushed by a European Union regulation that will prohibit the use of animals for collecting toxicological data on cosmetic ingredients beginning in 2009. Recentl ...

    SBIR Phase I 2010 Department of Health and Human Services
  7. Surface Enhanced Biocompatible Blood Oxygenators

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: NHLBI

    DESCRIPTION (provided by applicant): Compact Membrane Systems, Inc. proposes to develop novel blood oxygenator membranes with enhanced blood biocompatibility. These will be used to enhance conventional cardio bypass surgery minimizing post operative effects. In addition, they will provide a key element for long term blood oxygenation associated with extracorporeal membrane oxygenation, acute respi ...

    SBIR Phase I 2010 Department of Health and Human Services
  8. TCR-less Targeted T Cells Against Cancer

    SBC: CELDARA MEDICAL, LLC            Topic: NCI

    DESCRIPTION (provided by applicant): This year cancer will become the leading cause of death worldwide. The global burden of cancer doubled between 1975 and 2000. By 2020, it is projected to double again, and to triple by 2030. Ideally, any cancer therapy should be effective (at killing cancerous cells), targeted (i.e. selective, to avoid killing healthy cells), permanent (to avoid relapse and met ...

    SBIR Phase I 2010 Department of Health and Human Services
  9. ChNKG2D-Targeted Cellular Cancer Therapy: Preclinical Toxicology

    SBC: CELDARA MEDICAL, LLC            Topic: NHLBI

    DESCRIPTION (provided by applicant): Cancer is projected to become the leading cause of death worldwide by 2010. The global burden of cancer doubled between 1975 and 2000. By 2020, it is projected to double again, and to triple by 2030. Multiple myeloma (MM) is a particularly deadly type of cancer. In 2008, 19,920 Americans were diagnosed with MM, and 10,690 died. Five-year survival rates are on ...

    SBIR Phase I 2010 Department of Health and Human Services
  10. Angiogenesis antagonist plus CD40-TLR agonist adjuvant combination vaccine

    SBC: IMMURX LLC            Topic: NIAID

    DESCRIPTION (provided by applicant): The early infiltration by leukocytes into the tumor microenvironment leads to neovascularization, enhanced tumor growth, metastasis and lethality of the host. Notably, leukocytes enable tumor establishment, as suggested early on by Virchow in 1826 and proven more recently by others (e.g. Manning et al, 2007 Clin Ca Res 13:3951; review Wasiuk/Noelle et al. 2009 ...

    SBIR Phase I 2010 Department of Health and Human Services

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