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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. An innovative mechanized system for transferring tissue-cultured plantlets to propagation trays to revolutionize vegetable and floral crop production

    SBC: Alaska AgriTech Inc.            Topic: 813

    Tissue culture is a well-established micropropagation method for many vegetable and floral crops. However, transferring plantlets from tissue culture vessels to the propagation trays is extremely time consuming and labor intensive. It is the major obstacle in crop production. The purpose of this projectis to design and produce a prototype which can efficiently transfer plantlets to propagation tra ...

    SBIR Phase I 2016 Department of Agriculture
  2. Harnessing the anti-inflammatory potency of Alaska berries as a functional food

    SBC: Cereon Biotechnology LLC            Topic: 85

    A persistent and spreading inflammatory and oxidative stress is largely responsible for the progressive degeneration of neuronal connectivity ultimate reflected by a debilitating decline of cognitive function, which accompanies normal aging as well as age and/or trauma-related ailments. The yearly economic burden due to age-related cognitive decline is estimated to exceed $600 billion worldwide an ...

    SBIR Phase I 2016 Department of Agriculture
  3. Enhanced Membranes for Sweetening of Manure based BioGas

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: 88

    Every year over 1 billion tons of fresh animal manure is produced in US and it raises pollution concerns. "Anaerobic digestion" is an environmental friendly and energy efficient way to dispose animal manure. Animal manure is converted to biogas and digestate through this process. The animal manure digestate has a much less pollution potential than untreated animal manure and can be used as a chemi ...

    SBIR Phase I 2016 Department of Agriculture
  4. Novel SCD1 inhibitors for treatment of cancer

    SBC: MODULATION THERAPEUTICS, INC.            Topic: 102

    DESCRIPTION provided by applicant Metastatic clear cell renal cell carcinoma mccRCC is an incurable cancer with a year survival of less than for which novel therapeutic agents need to be developed urgently It is notoriously resistant to chemotherapy and radiation Although molecularly targeted therapies have led to an improvement in survival the benefit is rather limited due to event ...

    STTR Phase I 2016 Department of Health and Human Services
  5. A microchip to analyze trafficking leukocytes in Alzheimer’s disease patients

    SBC: IsoPlexis            Topic: NIA

    DESCRIPTION provided by applicant Alzheimerandapos s disease AD is one of the most common neurodegenerative diseases that lead to detrimental outcomes such as progressive memory deficit and cognitive impairment Although it is expected that the prevalence of AD will double over the next years currently no widely accepted molecular biomarkers for early detection or non invasive monitoring ...

    SBIR Phase I 2016 Department of Health and Human Services
  6. The Virtual HAZMAT Response Academy: Advanced Training Technology for HAZMAT Responders Using Next-Generation Internet

    SBC: World 2 Systems            Topic: 113

    DESCRIPTION provided by applicant This proposal addresses topics of interest to the NIEHS Advanced Training Technologies ATT Program to andquot develop ATT products that will support high quality health and safety training for hazardous materials workers emergency responders and skilled support personnel andquot We propose to develop a Web based Virtual HAZMAT Response Academy VHRA with ...

    SBIR Phase I 2016 Department of Health and Human Services
  7. Lake Cyanobacterial Harmful Algal Bloom Mapping and Analysis Platform (CHAB-MAP)

    SBC: APPLIED GEOSOLUTIONS LLC            Topic: NIEHS

    DESCRIPTION provided by applicant Concern over toxins and public health threats resulting from Cyanobacterial Harmful Algal Blooms CHABs have gained attention as reoccurring and seasonal blooms persist in many waters It has also been suggested that climate change is increasing the frequency intensity and duration of CHABs Broadly cyanotoxins can be described as having negative health im ...

    SBIR Phase I 2016 Department of Health and Human Services
  8. Leveraging advanced clinical phenotyping to enhance problem lists and support value-based healthcare

    SBC: VMT, INC.            Topic: NLM

    Project Summary As United States healthcare seeks to address inconsistent quality and overwhelming cost data and technology have become central to all suggested approaches With newly available electronic health data and massive growth in processing power the hardest challenges in using clinical data are becoming clear Big data holds the potential to enable personalized patient care population ...

    SBIR Phase I 2016 Department of Health and Human Services
  9. STEM Game to Educate and Promote Hearing Health and Science for 4th to 7th Grade

    SBC: CREARE LLC            Topic: 999

    DESCRIPTION provided by applicant The National Research Council recognizes that serious computer games can support new inquiry based approaches to science instruction providing virtual laboratories or field learning experiences that overcome practical and logistical constraints to student investigations With the nationally recognized need to encourage and enhance education in the Science Tec ...

    SBIR Phase I 2016 Department of Health and Human Services
  10. Single-cell multi-protein device for informative cellular function evaluation

    SBC: IsoPlexis            Topic: 100

    DESCRIPTION provided by applicant ELISpot including its variant FLUOROSpot remains the mainstay to measure true secretion of single cells and to assess cellular function e g immunity in the pre clinical and clinical settings However because it measures only one or two proteins per single cell and provides minimal biological information it has limited utility for measuring cell biology an ...

    SBIR Phase I 2016 Department of Health and Human Services

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