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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Development of Controlled Release In-transit Ripening Technology for Delivering Ready-to-Eat Fruits to Distribution Centers for Domestic and International Markets

    SBC: MIRTECH INC.            Topic: 85

    The objective of this project is to develop an in-transit ripening technology for pears that would help fulfill the long sought need of the industry, which is to deliver and display ripened ready-to-eat pears year-round at retail. The motivation is to overcome the limitations of the current supply chain logistics wherein fruits may be delivered to retail in lower than desirable consumer preferred ...

    SBIR Phase I 2016 Department of Agriculture
  2. Enhanced Membranes for Sweetening of Manure based BioGas

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: 88

    Every year over 1 billion tons of fresh animal manure is produced in US and it raises pollution concerns. "Anaerobic digestion" is an environmental friendly and energy efficient way to dispose animal manure. Animal manure is converted to biogas and digestate through this process. The animal manure digestate has a much less pollution potential than untreated animal manure and can be used as a chemi ...

    SBIR Phase I 2016 Department of Agriculture
  3. Novel SCD1 inhibitors for treatment of cancer

    SBC: MODULATION THERAPEUTICS, INC.            Topic: 102

    DESCRIPTION provided by applicant Metastatic clear cell renal cell carcinoma mccRCC is an incurable cancer with a year survival of less than for which novel therapeutic agents need to be developed urgently It is notoriously resistant to chemotherapy and radiation Although molecularly targeted therapies have led to an improvement in survival the benefit is rather limited due to event ...

    STTR Phase I 2016 Department of Health and Human Services
  4. A microchip to analyze trafficking leukocytes in Alzheimer’s disease patients

    SBC: IsoPlexis            Topic: NIA

    DESCRIPTION provided by applicant Alzheimerandapos s disease AD is one of the most common neurodegenerative diseases that lead to detrimental outcomes such as progressive memory deficit and cognitive impairment Although it is expected that the prevalence of AD will double over the next years currently no widely accepted molecular biomarkers for early detection or non invasive monitoring ...

    SBIR Phase I 2016 Department of Health and Human Services
  5. Circulating organ-enriched microRNAs as biomarkers of aging

    SBC: DIAMIR, LLC            Topic: NIA

    DESCRIPTION provided by applicant A number of academic groups and life sciences companies are developing and testing approaches to delay aging the most significant risk factor for the vast majority of serious human diseases Critical for these efforts is the development and validation of minimally invasive cost effective biomarkers of aging DiamiR a molecular diagnostics company has deve ...

    SBIR Phase I 2016 Department of Health and Human Services
  6. High definition pressure mapping and electromyography for female pelvic floor guided therapy

    SBC: Advanced Tactile Imaging, Inc.            Topic: N

    DESCRIPTION provided by applicant Urinary incontinence UI and overactive bladder OAB are highly prevalent in women and their prevalence is increased with the age In a representative United States survey UI was reported to affect from to of women The OAB prevalence estimates vary considerably among studies ranging from to These conditions are socially embarrassing causin ...

    SBIR Phase I 2016 Department of Health and Human Services
  7. Advanced laser system for photoacoustic endomicroscopy

    SBC: LIGHT AGE, INC.            Topic: 102

    DESCRIPTION provided by applicant The emerging light based imaging technique of acoustic resolution photoacoustic endomicroscopy AR PAEM enables visualization of subsurface tissues with microscopic resolution at depths of many millimeters AR PAEM images provide crucial information regarding microvasculature morphology and tissue physiology blood oxygenation For cancers originating in ...

    SBIR Phase I 2016 Department of Health and Human Services
  8. The Virtual HAZMAT Response Academy: Advanced Training Technology for HAZMAT Responders Using Next-Generation Internet

    SBC: World 2 Systems            Topic: 113

    DESCRIPTION provided by applicant This proposal addresses topics of interest to the NIEHS Advanced Training Technologies ATT Program to andquot develop ATT products that will support high quality health and safety training for hazardous materials workers emergency responders and skilled support personnel andquot We propose to develop a Web based Virtual HAZMAT Response Academy VHRA with ...

    SBIR Phase I 2016 Department of Health and Human Services
  9. Regenerative Technologies for Periodontal Reconstruction

    SBC: INNOVATIVE ELEMENTS, LLC            Topic: NIDCR

    DESCRIPTION provided by applicant Periodontitis the inflammation of the periodontium affects of the U S population Untreated periodontitis leads to progressive loss of the periodontal ligament cementum and alveolar bone ultimately resulting in tooth loss Bone grafting procedures are performed for patients with severe bone loss Autologous bone is harvested from retro molar area ...

    SBIR Phase I 2016 Department of Health and Human Services
  10. Lake Cyanobacterial Harmful Algal Bloom Mapping and Analysis Platform (CHAB-MAP)

    SBC: APPLIED GEOSOLUTIONS LLC            Topic: NIEHS

    DESCRIPTION provided by applicant Concern over toxins and public health threats resulting from Cyanobacterial Harmful Algal Blooms CHABs have gained attention as reoccurring and seasonal blooms persist in many waters It has also been suggested that climate change is increasing the frequency intensity and duration of CHABs Broadly cyanotoxins can be described as having negative health im ...

    SBIR Phase I 2016 Department of Health and Human Services

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