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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Natural biodegradable flocculants derived from hemoglobin

    SBC: VRM Labs            Topic: 84

    Antioxidants are a vital component of the food industry. Most of currently used antioxidants aresynthetic chemicals, and there is a global concern among regulatory bodies and customersregarding the safety of these compounds. However, natural antioxidants are more than ten timesmore expensive, and are often not as effective as their synthetic counterparts. Thus, there is a needfor inexpensive and c ...

    SBIR Phase I 2016 Department of Agriculture
  2. Developing the Use of the Dietary Inflammatory Index among Children (C-DII)

    SBC: Connecting Health Innovations, LLC            Topic: 85

    Through this proposal we offer a literature-derived, population-based dietary inflammatory index (C-DII) developed to characterize children diets on a scale from maximally anti- to pro-inflammatory. Diet is a strong moderator of chronic systemic inflammation. This C-DII will be used as a basis to:• Direct school lunch programs towards foods that will reduce inflammatrion-associated health ris ...

    SBIR Phase I 2016 Department of Agriculture
  3. Novel Natural Antioxidants Extracted from Animal Red Blood Cells

    SBC: VRM Labs            Topic: 85

    Antioxidants are a vital component of the food industry. Most of currently used antioxidants are synthetic chemicals, and there is a global concern among regulatory bodies and customers regarding the safety of these compounds. However, natural antioxidants are more than ten times more expensive, and are often not as effective as their synthetic counterparts. Thus, there is a need for inexpensive a ...

    SBIR Phase I 2016 Department of Agriculture
  4. Enhanced Membranes for Sweetening of Manure based BioGas

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: 88

    Every year over 1 billion tons of fresh animal manure is produced in US and it raises pollution concerns. "Anaerobic digestion" is an environmental friendly and energy efficient way to dispose animal manure. Animal manure is converted to biogas and digestate through this process. The animal manure digestate has a much less pollution potential than untreated animal manure and can be used as a chemi ...

    SBIR Phase I 2016 Department of Agriculture
  5. Novel SCD1 inhibitors for treatment of cancer

    SBC: MODULATION THERAPEUTICS, INC.            Topic: 102

    DESCRIPTION provided by applicant Metastatic clear cell renal cell carcinoma mccRCC is an incurable cancer with a year survival of less than for which novel therapeutic agents need to be developed urgently It is notoriously resistant to chemotherapy and radiation Although molecularly targeted therapies have led to an improvement in survival the benefit is rather limited due to event ...

    STTR Phase I 2016 Department of Health and Human Services
  6. Novel Dental Adhesives to Prevent Recurrent Caries

    SBC: CuRE Innovations, LLC            Topic: NIDCR

    DESCRIPTION provided by applicant Bacterial related marginal decay is the top reason for failure and retreatment of resin based composite restorations RBCs Retreatment of these restorations costs both the patients and insurance companies billions of dollars per year The weak point of the system is the zone known as the hybrid layer where the adhesive bonds the RBC to the dentin There are ...

    STTR Phase I 2016 Department of Health and Human Services
  7. Novel mechanism for the treatment of epilepsy: New Vitamin K analogs target energetics and have low toxicity due to excellent specificity and low dose requirements compared to current therapies

    SBC: Neuroene Therapeutics, LLC            Topic: 106

    DESCRIPTION provided by applicant Epilepsy is the th most common neurological disorder with in people developing epilepsy the occurrence of more than one unprovoked seizure at some point in their lifetime Unfortunately of all patients have intractable medication resistant epilepsy Thus new anti epileptic drugs AEDs that target alternative mechanisms of action are needed ...

    STTR Phase I 2016 Department of Health and Human Services
  8. A microchip to analyze trafficking leukocytes in Alzheimer’s disease patients

    SBC: IsoPlexis            Topic: NIA

    DESCRIPTION provided by applicant Alzheimerandapos s disease AD is one of the most common neurodegenerative diseases that lead to detrimental outcomes such as progressive memory deficit and cognitive impairment Although it is expected that the prevalence of AD will double over the next years currently no widely accepted molecular biomarkers for early detection or non invasive monitoring ...

    SBIR Phase I 2016 Department of Health and Human Services
  9. The Virtual HAZMAT Response Academy: Advanced Training Technology for HAZMAT Responders Using Next-Generation Internet

    SBC: World 2 Systems            Topic: 113

    DESCRIPTION provided by applicant This proposal addresses topics of interest to the NIEHS Advanced Training Technologies ATT Program to andquot develop ATT products that will support high quality health and safety training for hazardous materials workers emergency responders and skilled support personnel andquot We propose to develop a Web based Virtual HAZMAT Response Academy VHRA with ...

    SBIR Phase I 2016 Department of Health and Human Services
  10. Lake Cyanobacterial Harmful Algal Bloom Mapping and Analysis Platform (CHAB-MAP)

    SBC: APPLIED GEOSOLUTIONS LLC            Topic: NIEHS

    DESCRIPTION provided by applicant Concern over toxins and public health threats resulting from Cyanobacterial Harmful Algal Blooms CHABs have gained attention as reoccurring and seasonal blooms persist in many waters It has also been suggested that climate change is increasing the frequency intensity and duration of CHABs Broadly cyanotoxins can be described as having negative health im ...

    SBIR Phase I 2016 Department of Health and Human Services

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