Award Data

Tinea capitis scalp ringworm is a fungal dermatophyte infection of scalp hair follicles that afflicts of the U S pediatric population Tinea capitis is a major health care disparity because it occurs predominantly among individuals with a disadvantaged socioeconomic background and sub Saharan African descent Diagnosis of tinea capitis is currently dependent on culture and microscopy Both ...

PROJECT SUMMARY This proposal responds to RFA DC in which the NIDCD is seeking to support the development of acoustic signal processing tools that have the potential to accelerate research studies and to facilitate the translation of novel algorithms for hearing aids Approximately of American adults report some degree of hearing trouble and of Americans aged and over experi ...

PROJECT SUMMARY This proposal aims to develop a therapeutic capable of preventing and treating the severe sinus inflammation associated with chronic rhinosinusitis CRS CRS is a debilitating inflammatory disease of the sinuses that impacts over million Americans and substantially diminishes the quality of life and productivity of affected patients From to the total US health care ...

DESCRIPTION provided by applicant Sickle cell disease SCD is a severe inherited disease that occurs in about in newborns in the U S greater than that of any other condition detected by newborn blood screening Only one treatment hydroxyurea is approved for the complications of SCD in adult patients Hydroxyurea is not approved in children due to concerns regarding possible genotoxi ...

DESCRIPTION provided by applicant Metastatic clear cell renal cell carcinoma mccRCC is an incurable cancer with a year survival of less than for which novel therapeutic agents need to be developed urgently It is notoriously resistant to chemotherapy and radiation Although molecularly targeted therapies have led to an improvement in survival the benefit is rather limited due to event ...

The broader impact/commercial potential of this project centers on furthering scientific understanding of degradation in electrochemical energy storage. The project will explore technology that will enable the large-scale transfer of a key laboratory-proven diagnostic tool from the lab to the field. This tool, called electrochemical impedance spectroscopy (EIS), is a noninvasive assessment of the ...

This SBIR Phase 1 project will improve motivation, learning and self-esteem of children by incorporating well-established principles from behavioral psychology and gaming science. The innovation disrupts conventional paradigms by advantageously leveraging the exploding screen time trends of digital games and social media, which are commonly a nemesis to learning and attention span. Children's inte ...

Decline in cognitive ability is a major quality of life problem for many cancer survivors This problem is affected bywhich treatments a particular individual receives Unfortunately research has provided little guidance on whichtreatment may be best for an individual based on unfavorable cognitive side effects To help researchers fill thisinformation gap and provide doctors and patients with t ...

The broader impact/commercial potential of this project is in the development of a transformative carbon dioxide sequestration technology that can convert carbon dioxide and water directly into gasoline fuels with unprecedented efficiency, with sunlight as the only energy input. The technology is based on earth abundant metals as photo-catalysts, is environment- friendly, and potentially can be us ...

The broader impact/commercial potential of this project is to establish a precedence for remote, real time assessment of the safety and serviceability of infrastructural assets through the development of a self-powered structural health monitoring system. This piezoelectric fatigue fuse (PFF) will enable the establishment of quantifiable metrics to discern the current state of life as well as proj ...