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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Person-Centered Planning ToolKit: Development of an Application to Improve Workforce Participation Through Team Collaboration and Customized Employment Discovery Technology

    SBC: Assistech Systems LLC            Topic: Disabilities

    This project addresses the need for increased opportunities for customized employment for individuals with cognitive disabilities by developing the Person-Centered Planning ToolKit. The Toolkit will enhance implementation of personcentered planning (PCP), often limited by lack of follow-through on action items and a lack of tools to match career preferences to specific customized employment opport ...

    SBIR Phase I 2019 Department of Health and Human Services
  2. GreenCare Interactive Guide for Knee Replacement Surgery

    SBC: PEER Technologies PLLC            Topic: NIA

    Project SummaryAbstract The goal of this Phase I work is to finish development of an innovative interactive app designed to help patients appropriately use total knee replacementTKRsurgery and provide support to achieve best outcomesTKR is highly effective for treating advanced osteoarthritis of the kneebut it has risksAppropriate use can be assured by engaging patients in a Shared Decision Making ...

    SBIR Phase I 2018 Department of Health and Human Services
  3. A universal eye drop adherence monitor to measure and improve adherence to ocular medications

    SBC: Universal Adherence LLC            Topic: N

    Project Summary Abstract Universal Adherence is an emerging medical device company dedicated to improving adherence to ocular medications through innovative technical solutionsOur proposed Devers Drop DeviceDwill accurately track when a patient removes an eye drop bottle capcommunicate usage data wirelessly to a database that researchers can accessand send alerts to patients when a medication is d ...

    STTR Phase I 2018 Department of Health and Human Services
  4. A High-Throughput, Multi-Omic Assay of Tumor Biomarkers from Single-Cells

    SBC: IsoPlexis            Topic: 172

    SUMMARY Although solid tumors oftentimes arise from the uninhibited growth of a single aberrant cellthe population of cells within a tumor are genetically and molecularly heterogenousThis makes it very difficult to evaluate a therapy s efficacy when using bulk population measurementsFurthermorerecent research has implicated microRNAsmiRNAsas drivers of progression and malignancy in many tumor type ...

    SBIR Phase I 2018 Department of Health and Human Services
  5. Development of CM-SV1, a monoclonal antibody treatment for Sudan Virus

    SBC: CELDARA MEDICAL, LLC            Topic: NIAID

    PROJECT SUMMARY The filovirusesfamily Filoviridaecomprising five ebolavirusesa cuevavirusand two Marburg virusesare negative strand RNA viruses that cause severe hemorrhagic fever with up tohuman case fatality rateTheepidemic in Western Africacaused by the Zaire ebolavirusEBOVspecies demonstrated the potential for these viruses to cause dire health emergencies of global scopeand highlighted the ne ...

    SBIR Phase I 2018 Department of Health and Human Services
  6. Targeting leukocyte metabolism to treat human autoimmune disease

    SBC: Immunext, Inc.            Topic: R

    ImmuNext has defined an anti MCTmonoclonal antibodymAbthat will be developed for the treatment of human autoimmune diseaseThe membrane monocarboxylate nutrient transporter SLCAMCTis a multi pass transmembrane protein responsible for the facilitated transport of critical metabolitesincluding products of glycolysislactatepyruvate and ketonesOur strong preliminary data support the tenet that mAbs tha ...

    SBIR Phase I 2018 Department of Health and Human Services
  7. Smart Cavity Creator Drill for Lumbar Interbody Fusion

    SBC: PEER Technologies PLLC            Topic: NIBIB

    PROJECT SUMMARYABSTRACT Older patients with persistent and progressive symptoms of chronic back pain and leg pain often have a diagnosis of lumbar degenerative spondyolisthesis and undergo complex lumbar decompression and fusion surgeryOverof these procedures are performed in the United States each yearSurgery is highly effective but technically challengingOne technical challenge of fusion in spon ...

    SBIR Phase I 2018 Department of Health and Human Services
  8. HLS-Affordable, quantitative microchip-electrophoresis for sickle cell disease screening

    SBC: Hemex Health, Inc.            Topic: NHLBI

    PROJECT SUMMARY Sickle Cell DiseaseSCDaffectsAmericans and more thanmillion people globallyprimarily in economically disadvantaged populationsIt is estimated that nearlyof children born with SCD in these areas die before the age of fivealthoughcould be saved through simplecost effective treatments if diagnosed early according to World Health OrganizationEarly diagnosis of SCD remains a challenge i ...

    SBIR Phase I 2018 Department of Health and Human Services
  9. Specificity and safety of a targeted therapy against triple negative breast cancer

    SBC: CELDARA MEDICAL, LLC            Topic: 102

    PROJECT SUMMARY ABSTRACT Despite recent advances in the treatment of breast cancerBCthere is a pressing unmet medical need as BC remains the second leading cause of cancer related deaths among womenInnovative new approaches are especially needed to help patients with triple negative BCTNBCas TNBCandapos s inherently aggressive clinical behavior and the lack of recognized molecular targets for ther ...

    SBIR Phase I 2018 Department of Health and Human Services
  10. Nanoparticle Probes to Objectively Measure Pain Following Back Surgery

    SBC: PEER Technologies PLLC            Topic: NIDA

    AbstractPost operative pain is poorly managed and increases risk for delayed recoverychronic painopioid dependenceand persistent disabilityOne barrier to effective management of acute pain is the absence of objective measuresWe propose to conduct a feasibility study for technology to objectively measure postoperative painWe have selected back surgery as a model given its frequencycostand poor outc ...

    SBIR Phase I 2018 Department of Health and Human Services

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