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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Project Hi-Fi: Promoting High Fidelity Of Screening And Progress Monitoring Assessments

    SBC: Life Technologies            Topic: N/A

    This project team is developing a prototype of software for a tablet computer to replace paper tests for teachers to assess the reading fluency of special education students in grade 5 and 6. The technology will provide: scoring and tracking assessments with a stop watch for appropriate timing of questions, upload of data generated from the assessment directly to a database, audio playback capabil ...

    SBIR Phase I 2013 Department of Education
  2. Goal Guider: A Mobile and Web-Based System for Self-Management of Everyday Life by Individuals with Intellectual Disabilities and Autism

    SBC: Assistech Systems LLC            Topic: 84133S1

    The project goal is to develop and test the feasibility of a self-management system, Goal Guider, consisting of a mobile application and companion web site that allows individuals with intellectual disabilities and autism to effectively manage self-defined goals for everyday living across various personal, educational, and vocational life domains. Users will be able to easily enter goals, work wit ...

    SBIR Phase I 2013 Department of Education
  3. Safe And Effective Anti-CD154 Antibodies For Therapeutic Intervention

    SBC: Immunext, Inc.            Topic: NIAID

    DESCRIPTION (provided by applicant): There is compelling evidence that ?CD154 treatment has great potential in autoimmunity and graft rejection. Autoimmunity. Clinical efficacy of ?CD154 treatment has been seen in Lupus and idiopathic thrombocytopenia. In addition, Principal Investigator Dr. Noelle's clinical experience with ?CD154 is based on a Phase I trial in remitting/ relapsi ...

    STTR Phase I 2013 Department of Health and Human Services
  4. A Synthetic Human Cytomegalovirus Vaccine Platform

    SBC: TOMEGAVAX, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): The goal of this project is to synthesize, based on genomic sequence information, a human cytomegalovirus (HCMV) strain with demonstrated ability to establish persistent infection in sero-positive individuals. The resulting synthetic product will form the basis for the development of attenuated HCMV vaccines. Innovative synthetic biology methods will overcome ...

    STTR Phase I 2013 Department of Health and Human Services
  5. Instrumentation enabling a 16-fold decrease in oligonucleotide cost

    SBC: APDM, INC.            Topic: NIA

    DESCRIPTION (provided by applicant): Although balance and gait disorders are one of the most common and devastating chronic medical problems of older people, especially those with chronic neurological diseases, clinicians or clinical researchers do not measure balance and gait frequently, accurately, or sensitively. Our long-term goal is to develop and commercialize a unique system called the Hom ...

    SBIR Phase I 2013 Department of Health and Human Services
  6. Combination immunotherapies for the treatment of melanoma

    SBC: CELDARA MEDICAL, LLC            Topic: NCI

    DESCRIPTION (provided by applicant): Melanoma is the most common form of cancer in young adults1, and its incidence is rising at a rate higher than any of the seven most common cancers2, increasing 45% between 1992 and 20043. Plexxikon and Roche are codeveloping a BrafV600E inhibitor (i.e. PLX4032 (Vemurafenib)) and BMS/Medarex recently attained FDA approval for their anti-CTLA4 antibody (i.e. ...

    SBIR Phase I 2013 Department of Health and Human Services
  7. Selection-driven plant metabolites for treatment of CNS diseases

    SBC: COARE BIOTECHNOLOGY, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): Pancreatic ductal adenocarcinoma (PDAC) is a solid tumor and is the fourth leading cause of cancer-related death in the U.S. The 5-year survival rate of its victims is lt5%. There is increasing evidence that most solidtumors have a subpopulation of tumor-initiating cells termed cancer stem cells (CSCs). The inability to eradicate these CSCs is postulated to b ...

    SBIR Phase I 2013 Department of Health and Human Services
  8. A noninvasive optical imaging of retinal amyloid beta deposits in AD patients

    SBC: Oregon Center For Applied Science, Inc            Topic: NIDA

    DESCRIPTION (provided by applicant): Marital discord is a significant risk factor for a range of negative mental and physical health outcomes.1, 2 Individuals in unhappy relationships experience increases in stress, anxiety, functional impairment, and depressive symptoms3 and are at significant risk for substance abuse disorders.4-7 Furthermore, work loss associated with marital problems translate ...

    SBIR Phase I 2013 Department of Health and Human Services
  9. Integrin Targeted Therapy for the Treatment of Ovarian Cancer

    SBC: BIOSPEECH INC            Topic: NIDA

    Summary Sleep disordered breathing (SDB) is believed to be a widespread, under-diagnosed condition associated with detrimental health problems, at a high cost to society. The current gold standard for diagnosis of SDB is a time- consuming, expensive, and obtrusive (requiring many attached wires) sleep study, or polysomnography (PSG). The immediate objective of the proposed research is to develop a ...

    SBIR Phase I 2013 Department of Health and Human Services
  10. Wireless and Noise Attenuating Headset for Automated Hearing Screening

    SBC: CREARE LLC            Topic: NIDCD

    DESCRIPTION (provided by applicant): Hearing loss is a leading public health concern, with about 17% of American adults reporting some degree of impairment. Of those, fewer than 20% seek help for their condition for a variety of reasons. To address this issue, the National Institue of Deafness and Other Communication Disorders (NIDCD) is seeking solutions to improve hearing healthcare access and l ...

    SBIR Phase I 2013 Department of Health and Human Services

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