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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Improving the Ventilation of Motorcycle Helmets

    SBC: CREARE LLC            Topic: 151NH1

    Use of motorcycles helmets significantly reduces the risk of fatality or serious brain injury to riders in the event of a crash, but riders often do not wear helmets in warm weather because of thermal discomfort. We propose to develop an innovative ventilation and cooling system that will maintain a cool, dry environment inside the helmet while also meeting applicable safety standards. The key inn ...

    SBIR Phase I 2015 Department of Transportation
  2. Smart Sensing Dental Drill

    SBC: RYTEK MEDICAL, INC.            Topic: NIDCR

    DESCRIPTION provided by applicant Clinical Importance Almost million dental implants were placed worldwide in with million of these procedures taking place in the United States The worldwide market for these implants is expected to increase to $ $ billion in revenue by as dental implant manufactures target and train general dentists non surgically trained to perform th ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  3. Developing a Z-domain based latex agglutination assay for C. difficile toxins

    SBC: SAUREUS, INC.            Topic: NIAID

    DESCRIPTION provided by applicant The most common diarrhea in hospitals and nursing care facilities are attributed to toxins secreted by Clostridium difficile These toxins called Toin A TcdA and Toxin B TcdB are the primary markers for the diagnosis of C difficile associated diarrhea CDAD The gold standard for diagnosis of CDAD is isolation of the bacteria followed by cytotoxin detec ...

    SBIR Phase I 2015 Department of Health and Human Services
  4. Preclinical Development of BILT, a Next-Generation Immunotoxin Therapy for CTCL

    SBC: CELDARA MEDICAL, LLC            Topic: 102

    DESCRIPTION provided by applicant The long term aim of this project is to advance BILT for clinical approval which will provide clinicians with a powerful addition to the armamentarium for treating CTCL and cancer immunotherapy through depleting CD Treg Ontak R denileukin diftitox was making great strides in the treatment of CTCL since its FDA approval in until its discontinuation ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  5. A Single Cell Multi-Protein Device to Facilitate Cancer Immunotherapy

    SBC: IsoPlexis            Topic: 102

    DESCRIPTION provided by applicant The most promising immunotherapies against cancer rely upon modulating CD and various CD T cells to activate against cancers like melanoma lymphoma and leukemia However the ability for researchers to measure the secreted effector proteins per heterogeneous T cell which determine the cellular potency against the cancer is limited today This Phase ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  6. Development of a Real-Time, Wearable Sensor to Limit Exposure to Formaldehyde

    SBC: FreshAir Sensor, LLC            Topic: NIEHS

    DESCRIPTION provided by applicant The International Agency for Research on Cancer classified formaldehyde FA as a carcinogen based on inhalation caused squamous cell carcinoma in rats and leukemia and nasopharyngeal cancer in humans Formaldehyde may also be a cause of sinonasal cancer in humans Infants are particularly susceptible to effects from FA most likely as a result of the immaturit ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  7. Novel, Ambulatory Cuff-less Non-invasive Arterial Blood Pressure Monitor

    SBC: Krisara Engineering            Topic: NHLBI

    DESCRIPTION provided by applicant The objective of this proposal is to complete the engineering development and testing of the Non Invasive Self calibrating Ambulatory Multi Modality NISAM blood pressure device to recognize hypertensive patients not currently identified using todayandapos s technology As well as providing better management of hypertensive patients by presenting a truer roun ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  8. Design and Development of Immunotolerant S. aureus Biotherapies

    SBC: STEALTH BIOLOGICS LLC            Topic: NIAID

    DESCRIPTION provided by applicant Antibiotic resistance complicates the majority of Staphylococcus aureus S aureus infections as a full two thirds of hospital associated S aureus infections and of those acquired in the community are now methicillin resistant MRSA MRSA causes andgt infections in the US each year and it is responsible for half of all deaths caused by drug re ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  9. Video rate optical verification tool for radiotherapy treatment plans

    SBC: DoseOptics LLC            Topic: 393

    DESCRIPTION provided by applicant For the first time it is possible to directly visualize a radiation beam hitting a patientandapos s tissue or high resolution imaging of radiation delivery in water tank phantoms using Cerenkov emission imaging This allows the opportunity to do pre treatment verification at high resolution on patient verification of every delivered fraction or simply monit ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  10. Improved Protein Separations with Superficially Porous Particles

    SBC: ADVANCED MATERIALS TECHNOLOGY, INC.            Topic: 100

    DESCRIPTION provided by applicant Life sciences research and other critical bioanalytical applications would strongly benefit from faster and higher resolution liquid chromatographic HPLC separations of larger molecules including proteins peptides glycopeptides and glycans Many HPLC separations of biomedical interest such as resolution of protein mixtures require an hour or more and ma ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
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