Award Data

DESCRIPTION (provided by applicant): Summary: A laser-based acoustic emission (AE) detection device is proposed for work site structural stability assessment. This new device will take advantage of innovations in laser ultrasonics, artificial intelligence (Al) and advanced acoustic emission technology to provide mine workers with a unique instant, real time stability assessment of immediate rock ...

DESCRIPTION (provided by applicant): The aim of the proposed research is to develop tools for the prediction of the distribution of drug compounds in the human body. There is currently no experimental high throughput screening (HTS) method for determining compound tissue distribution. A drug compound's propensity to be taken up by different tissues and organs affects whether it will reach its acti ...

DESCRIPTION (provided by applicant): LED based curing lights are beginning to replace conventional halogen lamps as the first choice for dental photo-curing applications. The target of this proposal is to develop a new generation LED dental curing light. It will be the first curing light that is optimized according to the kinetic response of the dental composite, which plays a key role in determin ...

DESCRIPTION (provided by applicant): Most pharmaceutical synthesis involve condensation or dehydration reactions at some point in the process that generates water as a by-product. This water must be removed since (1) water is often not a desirable component of the finished product, (2) water limits conversion to final product, and (3) water generated slows the reaction rate. Many Pharmaceuticals h ...

DESCRIPTION (provided by applicant): Historically blood oxygenator technology either for short-term by-pass surgery or recently developed long-term strategies has been mass transfer limited by liquid side mass transfer fluid dynamics. Recent active mixing designs have led to systems which remove liquid side fluid limitations and have oxygen and carbon dioxide transport limited by membrane transpo ...

DESCRIPTION (provided by applicant): The objective of this proposed project is to achieve a major transformation in the technology used to assess self-care and social disability in children and youth. Measurement and practical requirements to identify disability and evaluate individual progress across pediatric age-groups and care settings present a serious dilemma to current fixed-item instrument ...

DESCRIPTION (provided by applicant): Vitamin B12 deficiency is a common problem that affects the general US population and the elderly in particular. The elderly are at risk for preclinical vitamin B12 deficiency due to the increased presence of B12 malabsorption and atrophic gastritis as a consequence of aging. The deficiency of vitamin B12 in the elderly has potentially serious complications inc ...

DESCRIPTION (provided by applicant): The long-term objective of this project is the development of a system based on high performance liquid chromatography (HPLC) for rapid and accurate antibiotic susceptibility testing of Mycobacterium tuberculosis (MTB). Susceptible and resistant strains of MTB, exposed to anti-MTB antibiotics, exhibit pronounced differences in mycolic acid content. Initial rese ...

DESCRIPTION (provided by applicant): The aim of this project is to enable accurate acquisition of distortion product otoacoustic emission (DPOAE) measurements in relatively high noise environments for use in hearing evaluations and screening. DPOAE measurements have been shown to be an effective and efficient method for screening infant, child, and adult hearing. Environmental noise, however, can ...

DESCRIPTION (provided by applicant): The specific aim of this project is to develop and demonstrate a low-cost, liquid oxygen (LOX) generation system to support ambulatory patients using Home Oxygen Therapy (HOT). Currently in the United States, yearly expenditures on HOT are nearly two billion dollars. These expenditures will increase dramatically over the next ten years due to the aging baby-boo ...