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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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A Randomized Blinded Placebo Controlled Clinical Trial to Evaluate Longeveron Mesenchymal Stem Cell LMSC Therapy for Treating The Metabolic Syndrome
SBC: Longeveron LLC Topic: NIAThe metabolic syndrome MetS is a cluster of factors that increases the risks for cardiovascular disease type diabetes mellitus and mortality and currently affects andgt of US adults MetS is associated with endothelial dysfunction decreased circulating endothelial progenitor cells EPCs and a pro inflammatory state We have made the exciting discovery that therapy with allogeneic me ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Cellular Immunotherapy for SSc
SBC: CELDARA MEDICAL, LLC Topic: NIAMSProject Summary Systemic sclerosis SSc is a systemic autoimmune disease that results in widespread fibrosis of the skin and internal organs vascular dropout and autoantibody formation SSc has the highest case fatality rate of any systemic autoimmune disease and there remain for FDA approved therapies Analysis of gene expression data on samples collected from SSc patients strongly indicates th ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Optimizing electrical impedance myography outcomes through data mining
SBC: MYOLEX, INC. Topic: NIAMSProject summary Electrical impedance myography EIM is a non invasive technology for the assessment of muscle that is based on the application of a weak high frequency electrical current to a muscle and the measurement of the resulting surface voltages The further development and application of EIM remains the main business focus of Skulpt Inc a small business concern based in Boston and San ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Functional integrated human on a chip systems for Alzheimer s research
SBC: HESPEROS, INC Topic: NIAProject Summary The goal of this proposal at the end of the Phase II effort is to have a service available to academia and industry to screen drugs for Alzheimer s to predict patient outcomes and determine how potential therapeutics are delivered to the CNS There are currently few companies able to offer multi organ evaluation with a recirculating medium utilizing functional readouts and none ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Development of a high-throughput screen to detect the effects of both pre- and post-biotransformed compounds for enhanced content drug discovery workflows
SBC: 490 BIOTECH INC Topic: 300Development of a high throughput screen to detect the effects of both preand postbiotransformed compounds for enhanced content drug discovery workflows Project Summary This Small Business Innovation Research Phase II project will build upon our successful Phase I demonstration that substrate free autobioluminescent signal generation can detect both the preand post biotransformed metabolic impacts ...
SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health -
Novel Inhibitors of PSMB and PSMB for the Treatment of Multiple Myeloma
SBC: InhiProt Topic: 103Multiple myeloma is incurable hematologic malignancy with an expected median survival of years The proteasome inhibitors bortezomib carfilzomib and the recently approved ixazomib are a mainstay of current myeloma treatment Despite an initial response rate approaching to proteasome inhibitor containing combinations all patients relapse and eventually become resistant to any treatments ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Development of PEGylated MTI for the treatment of relapsed Myeloma
SBC: MODULATION THERAPEUTICS, INC. Topic: 102ABSTRACT Modulation Therapeutics is developing a first in class cyclic peptide coined MTI for the treatment of multiple myeloma The company currently has a license for the parent molecule which has been awarded a patent covering the intellectual property for both composition of matter and use in cancer in the US and Europe Modulation Therapeutics is now poised to further advance this class ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Integration of a kidney module into a organ human on a chip system
SBC: HESPEROS, INC Topic: 400Project Summary Our overall strategy for Hesperos is to utilize microphysiological systems in combination with functional readouts to establish platforms capable of sophisticated analysis of chemicals and drug candidates for toxicity and efficacy during pre clinical testing with initial emphasis on predictive toxicity This is a service based company and is developing low cost in vitro systems u ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Preclinical characterization of THR to induce pancreatic beta cell regeneration Phase I
SBC: Ophysio Inc. Topic: NIDDKThe exocrine acinar ductal compartment of the pancreas has been hypothesized to harbor progenitor cells with the ability to give rise to new b cells The activation of such progenitors may potentially result in new b cell formation through differentiation rather than reprogramming We hypothesized that if pancreatic progenitors existed they would respond to bone morphogenetic protein BMP ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Low Cost Catalytic Biomass Cookstove for Improved Indoor Air Quality
SBC: MAINSTREAM ENGINEERING CORP Topic: NIEHSProject Summary An estimated billion people or about one third of the world s population rely on biomass fuel for cooking Emissions from biomass cookstoves contribute to global climate change indoor local air quality issues and related health effects In particular indoor air quality issues related to biomass cookstoves contribute significantly to rates of acute respiratory infection Re ...
SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health