Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until September, 2020.

  1. Enabling point-of-care molecular diagnostics by developing an adaptive PCR instrument and on-demand kit reagents

    SBC: BIOVENTURES, INC            Topic: 172

    Because of its high sensitivitypolymerase chain reactionPCRis the gold standard for the diagnosis of many infectious diseasesbut generally only implemented in well equipped laboratoriesOne of the major roadblocks for expanding PCR to point of care markets is the lack of simplerobustsingle tube PCR designs which preserve its laboratory based high sensitivity and specificityIn this Fast Track STTR a ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Targeting the checkpoint regulator VISTA for treatment of inflammatory disease

    SBC: Immunext, Inc.            Topic: R

    ImmuNext has identified and developed a putative lead anti VISTA monoclonal antibodymAbthat we aim to bring to the clinic for the treatment of human autoimmune diseaseVISTA is a member of the highly successful negative checkpoint regulatorNCRfamily of drug targetswhose members have demonstrated proven efficacy in inducing long term remissions in human cancersWe contend that antibodies that suppres ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Open Source System for Audio Processing

    SBC: CREARE LLC            Topic: NIDCD

    This proposal responds to RFA DCin which the NIDCD is seeking to support the development of acoustic signal processing tools that have the potential to accelerate research studies and to facilitate the translation of novel algorithms for hearing aidsApproximatelyof American adults report some degree of hearing troubleandof Americans agedand over experience bilateral hearing lossHLThehearing aid in ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  4. A single-cell mouse proteomic system to accelerate pre-clinical immune therapeutics

    SBC: IsoPlexis            Topic: 100

    With this PhasesubmissionIsoPlexis proposes to deliver a single cell proteomic solution for ultra sensitive detection of unique correlative biomarkers in pre clinical mouse modelsin an automated system that can be used to accelerate the discovery of potential immune therapeuticsThe recent revolution in new basic science discovery is failing to translate into improved patient treatmentThe reduction ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  5. A Hand-Held Robot to Cure BPH

    SBC: Virtuoso Surgical, Inc.            Topic: NIBIB

    Project Summary AbstractThe objective of this proposal is to transform a hand held surgical robotic system for transurethral laser prostate surgery from a lab prototype into a commercial productThe system will feature needle sized arms deployed through the endoscope port and will enable independent tissue manipulationlaser aimingand visualizationmaking surgery more accurate and ef cientClinical si ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Improved Thermal and Acoustic Comfort for Motorcycle Helmets

    SBC: CREARE LLC            Topic: 151NH1

    Use of motorcycles helmets significantly reduces the risk of fatality or serious brain injury to riders in the event of a crash, but riders often do not wear helmets in warm weather because of thermal discomfort. We propose to develop an innovative ventilation and cooling system that will maintain a cool, dry environment inside the helmet while also meeting applicable safety standards. The key the ...

    SBIR Phase II 2017 Department of Transportation
  7. An Aerosol Device for Delivery of Influenza Vaccine

    SBC: CREARE LLC            Topic: NA

    N/A

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  8. An Aerosol Device for Measles Vaccination (B)

    SBC: CREARE LLC            Topic: NA

    N/A

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
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