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THIS RESEARCH WILL DEVELOP A COMPUTER-BASED AID FOR PREVENTIVE HEALTH CARE PLANNING FOR INDIVIDUALS AND FAMILIES PREVAIL (PREVENTIVE HEALTH CARE PLANNING AID FOR FAMILIES) WILL AUTOMATE THE PROCESS OF ASSESSING AN INDIVIDUAL'S MEDICAL, DEMOGRAPHIC AND LIFESTYLE CHARACTERISTICS AND MAPPING THEM ONTO A PERSONALLY TAILORED SET OF PREVENTIVE HEALTH CARE RECOMMENDATIONS. THESE RECOMMENDATIONS WILL BE B ...

DEVELOPMENT OF ESTROGEN-RELATED DISEASES SUCH AS OSTEOPOROSIS, ENDOMETRIOSIS, ATHEROSCLEROSIS, AND BREAST CANCER IS RELATED TO "LIFE-STYLE" FACTORS WHICH INCLUDE DIET, REPRODUCTIVE ACTIVITY, OBESITY, AND EXPOSURE TO ENVIRONMENTAL AGENTS. THESE LIFE-STYLE FACTORS SHIFT THE BALANCE OF COMPETING ESTROGEN METABOLIC PATHWAYS, THE PRODUCTS OF WHICH EITHER PROMOTE OR INHIBIT THE PROLIFERATION OF ESTROGEN ...

EACH YEAR 50,000 PEOPLE SURVIVE A TRAUMATIC BRAIN INJURY (TBI) BUT ARE LEFT WITH COGNITIVE DEFICITS WHICH PREVENT THEIR RETURN TO NORMAL LIVING. THESE DEFICITS INTERFERE WITH THE INDIVIDUAL'S ABILITY TO USE SOFTWARE DEVELOPED FOR THE GENERAL POPULATION. A PILOT CASE STUDY INDICATED THE SUCCESS OF A PERSONAL PRODUCTIVITY SOFTWARE FOR A BRAIN INJURED INDIVIDUAL WHEN THE INTERFACE AND FEATURES OF THE ...

RELIABLE AND VALID ESTIMATES OF THE PREVALENCE OF SUBSTANCE ABUSE ARE CRUCIAL TO EFFECTIVE POLICY DEVELOPMENT, PREVENTION, AND EVALUATION IN SCHOOLS AND IN THE WORKPLACE. NUMEROUS METHODS FOR DERIVING THESE ESTIMATES HAVE BEEN TRIED, BUT ALL HAVE SIGNIFICANT FLAWS: UNDER-REPORTING, OBTRUSIVENESS, EXPENSE, ETC. PRIOR RESEARCH SUGGESTS THAT THE ITEM COUNT/PAIRED LIST (IC/PL) METHOD CAN BE ADAPTED TO ...

THE PURPOSE OF THIS WORK IS TO DEVELOP A NOVEL INTEGRATED STONE PHANTOM DEVICE, WHICH WOULD MONITOR AND DISPLAY THE CONDITION OF A PHANTOM STONE AS IT IS CRUSHED TO A POWDER BY AN EXTRACORPOREAL SHOCK WAVE LITHOTRIPSY SYSTEM. THE STONE PHANTOM DEVICE WILL DISPLAY THE NUMBER OF SHOCK WAVES OF A GIVEN ENERGY NECESSARY FOR STONE COMMINUTION, THEREBY TESTING THE LITHOTRIPTER'S SHOCK WAVE GENERATING, F ...

DYNAMIC DIGITAL DISPLAYS (3D), INC. WAS ESTABLISHED TO DEVELOP AND MARKET A HIGH-PERFORMANCE PHYSICIAN'S WORKSTATION WITH IMPROVED FACILITIES FOR REAL TIME, INTER- ACTIVE, THREE-DIMENSIONAL VISUALIZATION OF HUMAN ANATOMY AS DERIVED FROM CT, MR, OR PET SCANS. A PROTOTYPE DEVICE IS ALREADY OPERATIONAL AND GENERATES SHADED GRAPHICS IMAGES OF THREE-DIMENSIONAL ANATOMY ON A TWO-DIMENSIONAL VIDEO MONITO ...

THE CONCURRENT EVALUATION OF BRAIN ENERGY STATE AND OXYGEN DELIVERY PROVIDES A UNIQUE APPROACH TO "EARLY WARNING" OF HYPOXIC/ISCHEMIC STRESS. NEAR INFRARED SPECTROSCOPY OF OXYGEN DELIVERY BY HEMOGLOBIN GIVES AN APPROXIMATION TO THE OXYGENATION OF THE CAPILLARY BED OF THECORTICAL LAYERS OF THE NEONATE BRAIN. SPEED OF RESPONSE OF THE OPTICAL METHOD IS HIGH (.1 SEC OR LESS), AND APPROPRIATETO SUDDEN ...

IT IS PROPOSED THAT A PERSONAL COMPUTER (PC)-BASED SYSTEM BE DEVELOPED THAT WILL PROVIDE A COST-EFFECTIVE METHOD FOR COLLECTING, PROCESSING, AND ANALYZING IMAGE DATA IN ELECTRONMICROSCOPES. WIDESPREAD USE OF THIS TECHNOLOGY FOR HEALTH AND BIOMEDICAL RESEARCH WOULD BE FEASIBLE IF LESS EXPENSIVE INSTRUMENTATION WERE AVAILABLE. A PC-BASED SYSTEM IS NEEDED BECAUSE THE PRACTICAL UTILITY OF CURRENTLY AV ...

X-RAY ABSORPTION SPECTROSCOPY STUDIES OF DILUTE BIOLOGICAL SYSTEMS OF THE EXAFS TYPE ARE INHERENTLY INSENSITIVE RELATIVE TO OPTICAL ABSORPTION METHODS, AND SYNCHROTRON ORBITAL RADIATION IS OFTEN UNSTABLE AND NOISY IN ITS INTENSITY AND POSITION. THEREFORE, ANY STEPS TAKEN TO ACHIEVE THE THEORETICAL MAXIMUM SIGNAL/NOISE RATIO ARE OF PARAMOUNT IMPORTANCE IN INCREASING THE SCIENTIFIC DATA OUTPUT FROM ...