Award Data

DESCRIPTION provided by applicant This Phase IIB SBIR finalizes development conducts in depth preclinical testing and completes Verification and Validation of the Portable Transdermal Acoustic Patch TAP for Delivery of Large Molecules to Improve HIV Patient Medication Regime Compliance by Elimination of Side Effects Including Injection Site Reactions Nearly million people worldwide are ...

DESCRIPTIONprovided by applicantMolluscum contagiosumMCis a highly contagious skin disease caused by the poxvirusMCVMC appears as lesions on the body and face and can last months years before resolvingLesions occur most frequently in childrenand immune compromised individualsThe infection is confined to skin aloneit is not systemicTransmission spreads directly from person person contactautoinocula ...

DESCRIPTION provided by applicant The proposed Fast Track SBIR grant application is for the creation of a Web based Interactive Prevention Economic Impact Model PEIM which enables substance abuse prevention organizations to select cost effective evidence based interventions for specific target populations and estimate the economic impact of prevention using service delivery data and ...

DESCRIPTION provided by applicant In this NIH Phase IIB Competing Renewal SBIR project Actuated Medical Inc will finalize and clinically test the andquot Low Insertion Force Epidural LIFE Actuated Needle Insertion System for Enhanced Control and Tactile Feel andquot LIFE uses closed loop control of a vibrating needle to provide the clinician a more controlled entry through tough muscle a ...

DESCRIPTION provided by applicant Ocular irritation testing is extremely relevant to assuring adequate safety levels of public health as new formulations of chemicals and products are introduced In most cases these safety assessments are performed using the Draize Rabbit Eye test resulting in thousands of rabbits used in testing every year Alternatives have been discussed since the s with ...

DESCRIPTION provided by applicant The long term goal of this work is to develop an oral drug for the prevention of age related macular degeneration AMD AMD is the leading cause of blindness in the United States with million Americans diagnosed or at risk of irreversibly losing vision and over million people who already have debilitating vision loss Currently there is no FDA approved ...

DESCRIPTION provided by applicant This Phase II SBIR finalizes development and clinically tests Neo ET Clear an Actuated Low Stress Endotracheal Tube ETT Cleaner to Improve Neonate Lung Function Neo ET Clear suctions mucus from mm diameter neonatal endotracheal tubes with significantly reduced deleterious impact on lung function and mechanics as compared to current methods includin ...

DESCRIPTION provided by applicant Disparities in healthcare delivery and outcomes have been linked in part to the difficulties physicians have in establishing effective communication with patients who differ from themselves in terms of race ethnicity and economic circumstances Type diabetes mellitus and pre diabetic nutrition based obesity are an important case in point Racial and socio ...

DESCRIPTIONprovided by applicantHuntington s DiseaseHDis an inherited disease that results from expansion of a trinucleotideCAGcytosine adenine guaninerepeat that encodes a polyglutamine tract in the huntingtin proteinPsychiatric symptomsincluding irritability and aggressionare common in HD patientsThese are among the most distressing aspects of the diseaseThey have adverse effects on daily life a ...

DESCRIPTION provided by applicant Epigenetic proteins such as histone methyltransferases represent important potential drug targets for indications like cancers neurodegenerative disorders and cardiovascular and metabolic diseases At Reaction Biology Corporation andquot RBCandquot we are working toward the complete coverage of all epigenetic targets including HMTs to identify and impr ...