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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. High-throughput Prediction of Compound Tissue Distribution

    SBC: ANALYTICAL BIOLOGICAL SERVICES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The aim of the proposed research is to develop tools for the prediction of the distribution of drug compounds in the human body. There is currently no experimental high throughput screening (HTS) method for determining compound tissue distribution. A drug compound's propensity to be taken up by different tissues and organs affects whether it will reach its acti ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  2. LOW-COST AFFINITY SYSTEM FOR PREPARATION OF PLASMA/SERUM FOR BIOMARKER ANALYSIS

    SBC: APD LIFE SCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): We will develop a disposable, affinity-based capillary tube [AffiTip] that is capable of removing 99% of the interfering bulk protein from < 5 :L of undiluted plasma within 2 minutes for use prior to analysis for biomarkers [specific compounds that link mechanism of action and clinical effectiveness]. The product ultimately will be introduced at a sale price [p ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  3. Sphingosine Kinase Inhibitors as Anti-IBD Agents

    SBC: Apogee Biotechnology Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this program is to develop novel inhibitors of human sphingosine kinase (SK) that are effective as therapeutic agents. Because of its critical role in sphingolipid metabolism, we have focused on SK as an innovative molecular target for the development of new drugs for the treatment of Inflammatory Bowel Diseases (IBDs). Sphingolipids are being incre ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  4. Anti-Atherosclerosis Agents Targeting Sphingosine Kinase

    SBC: Apogee Biotechnology Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): Principal Investigator/Program Director: French, Kevin J. Abstract: The long-term goal of this program is to develop inhibitors of human sphingosine kinase (SK) that are effective as therapeutic agents. Because of its critical role in sphingolipid metabolism, we have focused on SK as an innovative molecular target for the development of new drugs for the treatm ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  5. Development of a Wearable Seizure Warning Device

    SBC: CHATTEN ASSOC., INC.            Topic: N/A

    DESCRIPTION (provided by applicant): In spite of advances in medical and surgical treatment, there are at any one time estimated to be some 350,000 individuals in this country whose seizures occur without warning and result in some combination of disordered thinking, impaired consciousness, or loss of motor control. Epileptologists and patients alike have long understood the magnitude of this prob ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  6. Bathing aids palliative cancer care &amp; aging-in-place

    SBC: AUGMENTECH, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): We propose developing bathing assistance technologies that are closely related at the device level for two very distinct, but important and underserved populations of potential users: 1) bedroom bathing for people with fragile skin receiving palliative care for advanced cancers and 2) ground floor bathing for elderly mobility impaired people who cannot afford t ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  7. Development Of A Pulsed Light Emitting Diode Dental Photocuring System

    SBC: B & W TEK INC            Topic: N/A

    DESCRIPTION (provided by applicant): LED based curing lights are beginning to replace conventional halogen lamps as the first choice for dental photo-curing applications. The target of this proposal is to develop a new generation LED dental curing light. It will be the first curing light that is optimized according to the kinetic response of the dental composite, which plays a key role in determin ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  8. Hybrid nanochannel arrays for single molecule linear, genome analysis

    SBC: BIONANOMATRIX, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The long term objective of this proposal is to develop a fully integrated chip and reader capable of single molecule analysis of linearized, native state genomic material. The anticipated embodiment will permit direct visualization and analysis of megabase fragments of DNA extracted directly from a sample (possibly a single cell) with resolution better than 400 ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  9. High resolution analysis of linear genomic DNA in Parallel nanochannel arrays

    SBC: BIONANOMATRIX, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): We are developing a nanochip device for manipulating long genomic DNA for high-resolution (kilobase), whole-genome analysis of cancer biomarkers such as gene amplifications, deletions, and translocations. These chromosome structural aberrations are strongly implicated in the process of malignant transformation and are important diagnostic, prognostic, a ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  10. Conformal Heat and Brachytherapy Surface Applicator

    SBC: BIONIX DEVELOPMENT CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): We believe therapeutic effect is enhanced when hyperthermia and radiation therapies are delivered simultaneously and when these two modalities are focused efficiently into the target disease. In Phase I, we constructed applicators that combine the uniform heating capabilities of conformal microwave array (CMA) printed circuit board applicators with an improved ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
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