Award Data

Reduced mass composite materials are crucial to the success of aerospace systems, but are inhibited by expensive autoclave consolidation, especially for large parts. To remedy this, NASA-LaRC has been developing cost-effective high-performance thermoplastic composite materials for years. NASA materials could dramatically reduce the cost of large aerospace structures, because those materials avo ...

DESCRIPTION (provided by applicant): An accurate physical model of a protein, based on its atomic coordinate data and created by rapid prototyping technology, is an effective new tool to communicate the essential details of a new structure to the bioc

DESCRIPTION (provided by applicant): Viral vectors are the most efficient tools currently available for genetic modification of mammalian cells in vitro and in vivo. However, because protocols for the incorporation of DNA of interest into viral particles

Reliable and sensitive detection of biowarfare agents (BWAs) such as Bacillus anthracis, Yersinia pestis, Francisella tularensis, ricin, botulinum toxin, etc. is an important challenge for both military operations and domestic anti-terrorism efforts. We are proposing to develop a biomimetic polymer coating, containing receptors for BWA targets, that becomes fluorescent when exposed to samples con ...

Reliable and sensitive detection of biowarfare agents (BWAs) such as Bacillus anthracis, Yersinia pestis, Francisella tularensis, ricin, botulinum toxin, etc. is an important challenge for both military operations and domestic anti-terrorism efforts. We are proposing to develop a biomimetic polymer coating, containing receptors for BWA targets, that becomes fluorescent when exposed to samples con ...

This goal is to construct a low-cost, polymeric, nanomaterial-based assay for the detection of multiple biological agents in a single device using our nanomanipulation technology to meet or exceed the sensitivity of the current two-line assays used in DoD applications. The nanodevice will exhibit no background streaking, cross bleeding, or other flow problems often associated with laminar flow de ...

Many rural areas and related small communities are on the lower side that separates areas with and without the telecommunications infrastructure necessary to compete in today's global economy. This project evaluates the application of fixed wireless communications technology for rural areas and develops a preliminary broadband network system design for Rusk County, a low-income rural county in Nor ...

Hoof and leg ailments resulting in lameness are the third most costly problem of dairy producers in the United States costing over $500 million annually with over 15% affected cows. In addition, lameness is a critical animal well-being issue. The inability to routinely and objectively diagnose lameness has hindered development of effective management practices. A novel device has recently been dev ...

The BMDS is being developed as a fully integrated, layered defense capable of defending against all ranges of threats. A critical aspect of this development is an integrated approach to interceptor allocation. A model-based framework for optimizing multi-layer BMDS performance, developing interceptor firing doctrine, and providing for adaptive, real-time interceptor allocation was developed in P ...

DESCRIPTION (provided by applicant): Current management of acute respiratory distress syndrome (ARDS) is suboptimal. Arteriovenous carbon dioxide removal (AVCO2R) combined with mild oxygen ventilation has shown promise. AVCO2R is mild pumpless technique u