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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. Anion Exchange Resins for Chirality-based Separation of Single-wall Carbon Nanotubes

    SBC: Sepax Technologies, Inc.            Topic: 9060663R

    Single chirality of single-walled carbon nanotubes (SWCNTs) is critical for their superb mechanical, thermal, optical and electronic properties. All known methods for producing nanotubes give mixtures of tubes with different chiralities. Physical separation of SWCNT by chirality is thus an enabling step for many potential applications and fundamental studies. The existing anion exchange resins are ...

    SBIR Phase I 2011 Department of CommerceNational Institute of Standards and Technology
  2. Novel Catalyst Systems

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): Transition metal catalysts are widely used in the pharmaceutical industry for the production of active ingredients, precursors and new drug candidates. These products must be very pure, often requiring labor and energyintensive separation processes, to achieve the required purity levels. Of special concern in the present context is to avoid contaminating the pr ...

    SBIR Phase I 2011 Department of Health and Human Services
  3. Customized Nanofiltration Membranes for Enhancing Pharmaceutical Manufacturing

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): The overall focus of this application is to develop nanofiltration membranes to recover the spent solvents generated from drug manufacturing processes allowing the solvents to be reused resulting in elimination of waste. This is also responsive to NIH RFP PA-09-100 entitled Energy Efficiency and Renewable Energy System Technology Research and Development . By ...

    SBIR Phase I 2011 Department of Health and Human Services
  4. Novel Materials and Methods for Separations of Glycopeptides and Glycans

    SBC: ADVANCED MATERIALS TECHNOLOGY, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): Analysis of glycoprotein polypeptide sites of carbohydrate attachment and the structures of the glycans present on these proteins requires the combination of high resolution chromatographic separations and sophisticatedmass spectrometry. Hydrophilic interaction liquid chromatography (HILIC) has great use in separations of glycopeptides and released glycans, exh ...

    SBIR Phase I 2011 Department of Health and Human Services
  5. Smaller Particle Fused-Core Silicas for Higher Performance Separations

    SBC: ADVANCED MATERIALS TECHNOLOGY, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): Life sciences research and other critical bioanalytical applications would strongly benefit from faster and higher resolution liquid chromatographic (HPLC) separations for both small molecules and larger molecules suchas proteins, peptides, glycopeptides, and glycans. Many HPLC separations of biomedical interest, such as proteomic or glycomic profiling, require ...

    SBIR Phase I 2011 Department of Health and Human Services
  6. Novel Nanofiltration Membranes for Isolation of Pharmaceutical Compounds

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: NCRR

    DESCRIPTION (provided by applicant): Novel Nanofiltration Membranes for Isolation of Pharmaceutical Compounds Project Summary: In the chemical manufacturing of pharmaceutical compounds, organic syntheses are often carried out in organic solvents and involve intermediates and final products with high added value. These pharmaceutical active compounds having molecular weights in the range of 300-200 ...

    SBIR Phase I 2011 Department of Health and Human Services
  7. Low Light Level Camera For Raman Spectroscopy

    SBC: B & W Tek Inc.            Topic: NCRR

    DESCRIPTION (provided by applicant): Raman spectroscopy is a potentially important clinical tool for real-time diagnosis of diseases and in situ evaluation of living tissues. However, the application of Raman spectroscopy for tissue evaluation has been limited by the strong tissue fluorescence that often overwhelms the extremely weak Raman signal. The goal of this proposal is to develop an infrare ...

    SBIR Phase I 2011 Department of Health and Human Services
  8. Enhanced Fluoropolymer Membrane Reactors for Production of Pharmaceutical Interme

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: NCRR

    DESCRIPTION (provided by applicant): The commercial syntheses of many pharmaceutical active ingredients and intermediates require acid catalysts and the removal of water to drive reactions to completion. Typical reactions include esterifications of carboxylic acids with alcohols, Friedel-Crafts acylations and alkylations, Schiff base, acetal and ketal formation and nitrations of aromatic compounds ...

    SBIR Phase I 2011 Department of Health and Human Services
  9. GPU-Accelerated Sparse Matrix Solvers for Large-Scale Simulations

    SBC: EM PHOTONICS INC            Topic: S601

    At the heart of scientific computing and numerical analysis are linear algebra solvers. In scientific computing, the focus is on the partial differential equations (PDEs) that arise from computational fluid dynamics (CFD), climate modeling, astrophysics, and structural and heat analysis that cannot be solved analytically. Certain problem formulations lead to sparse matrices, in which the majority ...

    SBIR Phase II 2011 National Aeronautics and Space Administration
  10. RF Front End Based on MEMS Components for Miniaturized Digital EVA Radio

    SBC: ALPHASENSE, INC.            Topic: O104

    In this SBIR project, AlphaSense, Inc. and the Carnegie Mellon University propose to develop a RF receiver front end based on CMOS-MEMS components for miniaturized digital EVA radio applications. In Phase I, we have proven the feasibility of implementing a compact, low power and high performance S band receiver front end based on CMOS- MEMS components. Specifically, we conducted link budget analys ...

    SBIR Phase II 2011 National Aeronautics and Space Administration

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