Award Data

Single chirality of single-walled carbon nanotubes (SWCNTs) is critical for their superb mechanical, thermal, optical and electronic properties. All known methods for producing nanotubes give mixtures of tubes with different chiralities. Physical separation of SWCNT by chirality is thus an enabling step for many potential applications and fundamental studies. The existing anion exchange resins are ...

This Small Business Innovation Research (SBIR) Phase I project will investigate the feasibility of developing a laser-based rapid monitoring gauge for accurate non-contact downhole stress measurement in drilling operations of the geosciences and oil and gas industries. Conventional downhole stress measurement, which commonly uses hydrofracturing, is complex, slow, inaccurate and detrimental to the ...

DESCRIPTION (provided by applicant): Most training curricula for first responders and Skilled Service Personnel (SSP) has been focused on chemical, biological, natural disaster (hurricane, flood), and pandemic response. However, training curricula regarding response to radiological events has been limited. Although some basic training exists for small radiological events, training that focuses on ...

DESCRIPTION (provided by applicant): Transition metal catalysts are widely used in the pharmaceutical industry for the production of active ingredients, precursors and new drug candidates. These products must be very pure, often requiring labor and energyintensive separation processes, to achieve the required purity levels. Of special concern in the present context is to avoid contaminating the pr ...

DESCRIPTION (provided by applicant): The overall focus of this application is to develop nanofiltration membranes to recover the spent solvents generated from drug manufacturing processes allowing the solvents to be reused resulting in elimination of waste. This is also responsive to NIH RFP PA-09-100 entitled Energy Efficiency and Renewable Energy System Technology Research and Development . By ...

DESCRIPTION (provided by applicant): Analysis of glycoprotein polypeptide sites of carbohydrate attachment and the structures of the glycans present on these proteins requires the combination of high resolution chromatographic separations and sophisticatedmass spectrometry. Hydrophilic interaction liquid chromatography (HILIC) has great use in separations of glycopeptides and released glycans, exh ...

DESCRIPTION (provided by applicant): Life sciences research and other critical bioanalytical applications would strongly benefit from faster and higher resolution liquid chromatographic (HPLC) separations for both small molecules and larger molecules suchas proteins, peptides, glycopeptides, and glycans. Many HPLC separations of biomedical interest, such as proteomic or glycomic profiling, require ...

DESCRIPTION (provided by applicant): We propose a commercial product composed of a computerized microscope system that allows investigators to perform automated cell counting and measuring using design-based stereology (DBS), as well as automated reconstruction of cytoarchitecture (ROC), on tissue sections from the nervous system. DBS has become the standard methodology for quantitative histology ...

DESCRIPTION (provided by applicant): Novel Nanofiltration Membranes for Isolation of Pharmaceutical Compounds Project Summary: In the chemical manufacturing of pharmaceutical compounds, organic syntheses are often carried out in organic solvents and involve intermediates and final products with high added value. These pharmaceutical active compounds having molecular weights in the range of 300-200 ...

DESCRIPTION (provided by applicant): Raman spectroscopy is a potentially important clinical tool for real-time diagnosis of diseases and in situ evaluation of living tissues. However, the application of Raman spectroscopy for tissue evaluation has been limited by the strong tissue fluorescence that often overwhelms the extremely weak Raman signal. The goal of this proposal is to develop an infrare ...