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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. SBIR Phase I: Novel, Robust Process for Thin, Dense Ceramic Coatings

    SBC: SOLUTION SPRAY TECHNOLOGIES LLC            Topic: MI

    This Small Business Innovation Research Phase I project is aimed at development of a novel, low-cost process for manufacturing environmental barrier coatings (EBCs) for ceramic matrix composites (CMCs) in aviation gas turbines. A key limitation for CMC adoption is the unavailability of inexpensive, truly gas impervious EBCs to provide required CMC engine service life. While novel EBC compositions ...

    SBIR Phase I 2017 National Science Foundation
  2. Assembled Porous Silica Membranes for Biomolecule SPE

    SBC: ADVANCED MATERIALS TECHNOLOGY, INC.            Topic: 400

    Abstract Life sciences research and other critical bioanalytical applications would strongly benefit from faster and higher efficiency sample preparation processes Sample preparation before high resolution analytical methods such as HPLC or LC MS can require effort and cost nearly equivalent to the actual sample analysis and data reduction Often sample preparation for proteomic glycoproteom ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Developing an integrated sorting and single cell analysis tool for the analysis of rare T Cells subsets in Autoimmunity

    SBC: ISOPLEXIS CORPORATION            Topic: R

    Autoimmune disease AD affects up to million Americans which costs approximately $ billion on health care annually and accounts for one of the leading causes of death in women T cells and cytokine function play an important role in autoimmune diseases such as Type Diabetes Multiple Sclerosis Rheumatoid Arthritis RA and Systemic Lupus Erythematosus SLE The most successful auto i ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Precision quality check of immunotherapeutics via single-cell cytokine mapping

    SBC: ISOPLEXIS CORPORATION            Topic: 102

    Adoptive transfer of autologous T cells engineered to express chimeric antigen receptorsCARshas emerged as a promising immunotherapy for patients with hematologic malignanciessuch as CDCARs in leukemias and lymphomasHoweverchallenges remain in terms of manufacturing consistency and the functional profile of the CAR T cell productsince infused cellsasliving drugscan be activated and release a varie ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Enhanced Oxidative Dehydrogenation of Ethane with Facilitated Transport Membranes for Low Cost Production of Ethylene

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: 17a

    Ethylene demand is expected to increase by 50% domestically and worldwide over the next 5 years. Much of this and future growth is likely to be met from shale gas based ethane. Dr. Anne Gaffney of the US-DOE has invented a mixed metal oxide catalyst, M1, for the oxidative dehydrogenation of ethane (C2- ODH) to ethylene at high conversions and very high selectivities. A major hurdle for commercial ...

    SBIR Phase I 2017 Department of Energy
  6. Flux Monitoring on an X-Ray Refractive Diamond Lens

    SBC: Delaware Diamond Knives, Inc            Topic: 05d

    Synchrotron-based science has had a great scientific impact and will continue to have great impact going forward. In spite of the large investment in the 3rd generation light sources, most beam lines do not preserve the source’s phase profile or brightness all the way to the sample. For these high brightness light sources, errors are almost completely due to distortion ...

    SBIR Phase I 2017 Department of Energy
  7. Diamond Strip Detectors for Charged Particle Tracking, 24b

    SBC: Applied Diamond, Inc.            Topic: 24b

    Applied Diamond will make large area particle detectors of CVD diamond for use in nuclear physics experiments at DOE and other laboratories. These detectors will reduce the operating expense and increase the capabilities of these facilities accelerating advances in nuclear science.

    SBIR Phase II 2017 Department of Energy
  8. High Oxygen/Nitrogen Selectivity Membrane

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: 12d

    This program develops a novel membrane module which produces low cost oxygen enriched air. This program will 1) reduce energy requirements for small or medium size furnaces by up to 60% and 2) provide high CO2 concentration exhaust streams for enhanced concentrating of CO2 for CO2 sequestering.

    SBIR Phase II 2017 Department of Energy
  9. Osteopontin targeted therapy for primary CNS lymphoma

    SBC: MODULATION THERAPEUTICS, INC.            Topic: 102

    Abstract Primary central nervous system lymphoma PCNSL is an aggressive brain tumor with a dire unmet therapeutic need It has an overall incidence of per person years and is regarded as an orphan disease with potential for fast track approval Our group made a discovery via gene expression analysis that osteopontin OPN is the most upregulated gene in PCNSL compared to its non CNS ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Robust Predictor of Breast Cancer Risk

    SBC: Morgan and Mendel Genomics, Inc.            Topic: 103

    Summary Approximatelymillion women in the United States are at high risk for developing breast cancerbased on inheritance of a germline mutation in a gene in the double strand breakDSBrepair and cyclin checkpoint pathwaysMany are unaware of their genetic predispositionsbecause their family history is uninformative or unknownGenetic testing is important for identifying mutations in these genesbut i ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
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