Award Data

Circular RNAs (circRNAs) are a novel class of non-coding RNAs that are an abundant component of the epitranscriptome. Putative functions of circRNAs, include miRNA sequestration, RNA-binding protein scaffolding, mRNA trapping, and protein translation regulation. Deregulation in one or more of these roles has been linked to several types of cancer, including pancreatic cancer, basal cell carcinoma, ...

Modern DoD applications are benefiting from the proliferation of EO/IR sensor technology. As imagers become cheaper and smaller, they are being more widely deployed for a variety of scenarios. This trend is exemplified by the Navys Future Targeting System (FTS), which will provide laser designation, laser spot imaging, and some target location functions in a single 5.5-pound unit, replacing discre ...

This STTR Phase I project will undertake the development of iron coordination complexes as alternatives for gadolinium contrast agents which are currently used in clinical MRI diagnostic exams. New MRI contrast agents are needed to serve the segment of the population who cannot tolerate Gd(III) agents. This includes patients with kidney disease and those who have frequent MRI scans and may accumul ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project will serve two complementary unmet market needs by: (1) accelerating the evaporation rate of brine ponds and enhancing salt production efficiency by 2-3 times; (2) condensing the moisture evaporated from contaminated/salty water so that one can obtain clean drinking water with n consumption of ...

This Small Business Innovation Research Phase I project will result in the development of smart, self-healing nanocapsules as anticorrosive pigment additive for commercialization of sustainable, economical and metal free acrylic, epoxy or polyurethane based anticorrosive coatings. The nanocapsule additive based anticorrosive coating will meet and exceed the performance of solvent and heavy metals ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) project is to produce polymer composites that enable commercialization of alkaline electrochemical devices, such fuel cells and electrolyzers. The use of fuel cell technologies will help preserve the environment, mitigate climate change, decreasing our carbon footprint and securing renewable energy supply. El ...

The broader impact of this Small Business Innovation Research (SBIR) Phase I project is to equip consumers with a scientific tool to measure and control their exposure to ultraviolet (UV) radiation, thereby mitigating their risk of getting skin cancer while enjoying the benefits of sunlight such as Vitamin D and outdoors activities. In the United States, skin cancer has become a major public healt ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is to provide clinical decision support software that assists inpatient providers in improving care for preventable acute inpatient harms, and thereby reduce mortality and morbidity. This grant develops a cloud-based platform that applies machine learning (ML) algorithms in real-time on data e ...

This SBIR Phase I project serves a national need for stronger career readiness by connecting youth to project- and work-based learning experiences that will help them to apply and extend classroom learning. These experiences will increase their career self-efficacy and skills, and help them to develop a critical understanding of careers and the work environment, at an age when it matters the most? ...

The broader impact/commercial potential of this project is improved navigation outcomes for blind and visually impaired (BVI) persons, approximately 285 million people worldwide according to World Health Organization (WHO) estimates. Orientation and Mobility (O&M) is very challenging for the BVI persons, and is rated as one of their two most significant stressors. The company aims to commercialize ...