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The Award database is continually updated throughout the year. As a result, data for FY21 is not expected to be complete until September, 2022.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Infectious Disease Diagnostics and Differentiation of Viral vs. Bacterial Infections for Point ofCare Applications

    SBC: GeneCapture, Inc.            Topic: CBD15C001

    GeneCapture, Inc. is proposing to develop a rapid in vitro diagnostic prototype using our patented molecular-based CAPTURE (ConfirmActive Pathogens Through Unamplified RNA Expression) assay. Based on the results and experience gained in our Phase I STTR contractHDTRA1-16C-0061: Infectious Disease Diagnostics and Differentiation of Viral vs. Bacterial Infections for Point of Care Applications, we p ...

    STTR Phase II 2018 Department of DefenseOffice for Chemical and Biological Defense
  2. Medical Countermeasure Development for Viral Induced Encephalitis Using Single DomainAntibodies

    SBC: Abzyme Therapeutics, LLC            Topic: CBD161004

    Alphaviruses, infection with which may cause encephalitis and death, are recognized as potential biological warfare agents. There are noapproved medical countermeasures against Alphaviruses. In Phase I, using Abzymes proprietary in vivo Self-Diversifying Camelid SingleDomain Antibody Library (SDALib) platform, broadly reactive single domain camelid VHH antibodies against equine encephalitis viral ...

    SBIR Phase II 2018 Department of DefenseOffice for Chemical and Biological Defense
  3. Hermetic Seals for Chemical/Biological Protective Garments

    SBC: CREARE LLC            Topic: CBD13109

    Interfaces on existing military chemical/biological protection garments are not designed to fully eliminate macroscopic and microscopic air gaps at folds, fabric surfaces, or hook-and-loop closures, and thus do not provide a hermetic barrier against exposure. Creare is developing hermetic garment closure systems that seal macroscopic and microscopic gaps at interfaces and closures and provide high ...

    SBIR Phase II 2018 Department of DefenseOffice for Chemical and Biological Defense
  4. Microfiber-Based Closures with Hermetic Sealing for Chem Bio Protective Garments

    SBC: NANOGRIPTECH            Topic: CBD13109

    Future engagements (especially with near-peer threats) present the possibility of a wide range of anticipated operational situations involving the presence of chemical threat agents. With this, deployment of Military Working Dogs (MWDs) is likely. This creates a situational awareness that MWDs are potentially at risk from exposure to a wide range of hazardous chemicals. Potential threat agents inc ...

    SBIR Phase II 2018 Department of DefenseOffice for Chemical and Biological Defense
  5. Host-Targeted Antiviral Drugs Providing Rapid, Scalable, Stable, Broad-Spectrum MedicalCountermeasure Against Marburg Virus

    SBC: Evrys Bio, LLC            Topic: CBD18A002

    In a pandemic or exposure to weaponized Marburg virus the morbidity, mortality and social unrest that will ensue before vaccines orMilitary operating on foreign soil as well as to the population of the US Homeland. Practically all threat agents of biological origin (except forcertain non-proteinaceous toxins, typically produced by marine organisms and fungi) have their structure and vital function ...

    STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
  6. Tomographic Nanoscopy for Pathogen Identification

    SBC: SOLID STATE SCIENTIFIC CORPORATION            Topic: CBD171003

    This effort will augment the capabilities of an existing all reflecting, confocal FTIR microscope to allow for digital holographic imaging as wellspectral content determination at video frame rates. The use of a dual beam frequency comb, with a beam path coincident with the pathrequired for the digital holographic imaging, will allow spectral determination of any organism being holographically ima ...

    SBIR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
  7. Novel Circulating RNA-based Markers as Diagnostic Biomarkers of Infectious Diseases

    SBC: CFD Research Corporation            Topic: CBD18A001

    In resource limited settings, rapid and accurate diagnosis of infections is critical for managing potential exposures to highly virulent pathogens,whether occurring from an act of bioterrorism or a natural event. This is especially important for hard to detect intracellular bacterial andalphavirus infections, that overlap symptomatically and often treated empirically due to a lack of reliable and ...

    STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
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