Award Data

DESCRIPTION (provided by applicant): In 2001 the US EPA lowered the maximum contaminant level for arsenic in drinking water from 50 ppb to 10 ppb, based on studies indicating the lower limit would prevent a significant number of cancer deaths and other il

NOAA collects meteorological measurements in open ocean and coastal marine environments from research vessels, data buoys and commercial ships for use in numerical weather prediction, global climate change research, and severe storm identification. The current system cost for robust marine automated meteorological stations is too high to allow ubiquitous use on all the available platforms. Throu ...

Our Phase I effort was successful. We upgraded our baseline methane analyzer to meet or surpass the levels of performance posed by DOC solicitation subtopic 8.1.1R: sensitivity of 10 ppb (dry mole fraction), low maintenance for extended periods at remote field sites, less than one liter (NTP) of reference gas per day, and negligible response to platform motion. The analyzer is a novel applicatio ...

DESCRIPTION (provided by applicant): Endostatin is a 20 kDa non-glycosylated protein that is a specific inhibitor of endothelial proliferation and a potent anti-angiogenesis agent. The therapeutic effects of endostatin have been difficult to evaluate f

DESCRIPTION (provided by applicant): B-Interferon is a fibroblast-derived cytokine that exhibits antiviral, anti-proliferative and immunomodulatory effects on many cell types. Recombinant human B-interferon has proven effective in treating Multiple Scl

DESCRIPTION (provided by applicant): Progress in medical research worldwide is dependent on the safe, rapid, reliable and convenient exchange of biological specimens that are optimally preserved. Without the confidence that cryopreserved specimens bein

DESCRIPTION (provided by applicant): Occupational exposures to hexavalent chromium, Cr(VI), occur during the production and use of stainless steel, chromate chemicals, and chromate pigments and operations such as chrome plating and coating processes. NIOSH considers all Cr(VI) compounds to be potential occupational carcinogens, and an increased risk of lung cancer has been demonstrated in exposed ...

This Small Business Innovation Research project addresses development of a field-deployable monitor for detecting chemical warfare agents (CWAs) and toxic industrial chemicals (TICs) by their infrared spectrochemical signature. Phase I studies demonstrat

The NOAA Environmental Technology Laboratory seeks to perform advanced wide-area mapping of soil moisture and salinity. This requires a large scanning antenna with aerodynamic form, narrow beamwidth, high efficiency, and dual polarization. This antenna system must provide operation at L-band (1400-1427 MHz) and C-band (6.0-6.5 GHz). This large aperture must maintain stable performance independe ...

DESCRIPTION (provided by applicant): With its ability to secrete high levels of recombinant proteins, the yeast Pichia pastoris is extensively used for protein manufacturing. However, as actual yields vary widely for individual proteins, GlycoFi is focusing on the improvement of protein yields in P. pastoris as part of the company's long term mission to develop yeast-based protein production tech ...