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The Award database is continually updated throughout the year. As a result, data for FY21 is not expected to be complete until September, 2022.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. A Device for Measuring Gas Polarization

    SBC: Advanced Liquid Crystal Technologies            Topic: N/A

    DESCRIPTION (provided by applicant): This project is to develop an instrument to measure the polarization of a hyperpolarized noble gas, Helium- 3 and Xenon-129, for enhanced lung MRIs in a clinical environment. It is essential to have some means of measuring polarization at various stages in the handling of these gases, e.g. at production, storage, transport and administration to a patient. Th ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  2. An Aerosol Device for Measles Vaccination

    SBC: CREARE LLC            Topic: NA

    N/A

    SBIR Phase II 2000 Department of Health and Human ServicesNational Institutes of Health
  3. An Aerosol Device for Measles Vaccination (B)

    SBC: CREARE LLC            Topic: NA

    N/A

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  4. A novel pattern-based framework for genetic analysis

    SBC: HIGH THROUGHPUT BIOLOGY, INC            Topic: N/A

    DESCRIPTION (provided by applicant): The sequencing of the human genome, along with the development of high-throughtput technologies in genomics, provides an unparalleled opportunity to advance our understanding of the roles of genetic factors in human health, disease, and drug response. Genetic dissection of complex disease and variations of drug response has become one of the most important ge ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  5. CYTOMEGALOVIRUS DETECTION USING NONRADIOACTIVE DNA PROBES IN SITU

    SBC: Ert            Topic: N/A

    CYTOMEGALOVIRUS (CMV), A MEMBER OF THE HERPES VIRUS GROUP, IS PRESENT IN THE BLOOD OF A LARGE PORTION OF THE HUMAN POPULATION. ADMINISTRATION OF THIS BLOOD TO HIGH-RISK PATIENTS MAY RESULT IN DEATH. ENZO PROPOSES THE DEVELOPMENTOF A QUICK, SPECIFIC, EASY AND ECONOMICAL DIAGNOSTIC TEST, BASED ON NONRADIOACTIVE DNA-DNA HYBRIDIZATION, TO DIRECTLY SCREEN HUMAN BLOOD FOR CMV. PHASE I DEVELOPMENT WILL B ...

    SBIR Phase II 1987 Department of Health and Human Services
  6. DESIGN OF A HIGH SPEED, HIGH RESOLUTION SIDE SCAN SONAR SYS TEM

    SBC: KLEIN ASSOC., INC.            Topic: N/A

    SIDE SCAN SONAR HAS DEVELOPED TO THE POINT WHERE IT IS NOW AN ACCEPTED PART OF HYDROGRAPHIC CHARTING PROJECTS, AS WELL AS A BROAD RANGE OF OCEAN SEARCH AND SURVEY APPLICATIONS. ONE LIMITATION ON ITS UTILITY, HOWEVER, IS THE REQUIREMENT TO OPERATE THE SYSTEM AT RELATIVELY LOW SPEEDS (5 KNOTS OR LOR LESS) IN ORDER TO ACQUIRE HIGH-QUALITY DATA. ANY INCREASEIN VESSEL SPEED CAPABILITY WOULD RESULT IN G ...

    SBIR Phase II 1987 Department of Commerce
  7. Development of an inhibitor of VEGF expression

    SBC: PTC THERAPEUTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Up-regulation of vascular endothelial growth factor (VEGF), a key factor for angiogenesis, is an important contributor to the pathogenesis of cancer. The abundance of VEGF is in large part controlled at the posttranscriptional levels by sequences in both the 5'- and 3'-untranslated regions (UTRs) of its mRNA. The 5'- UTR contains an internal ribosomal entry sit ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  8. Development of a Submersible Fish Cage for Open Ocean Aquaculutre

    SBC: JPS Industries, Inc.            Topic: 831

    A need exists to develop cost effective and reliable submersible cage technology for exposed aquaculture. The team assembled as part of this SBIR incorporates JPS Industries, Great Bay Aquafarms and the University of New Hampshire. In Phase I, a design will be developed based on concepts known to work in the industry. Concepts to be investigated include a cage constructed around HDPE pipe, with ...

    SBIR Phase II 2005 Department of Commerce
  9. Device for Eradicating /Controlling Biofilm in Dialysis

    SBC: NOVAFLUX TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The clinical significance of chronic pro-inflammatory reactions in hemodialysis patients due to exposure to endotoxins has become a central issue in nephrology in recent years. The European Renal Association urges the routine use of ultrapure dialysate with bacteria and endotoxin levels < 0.1 cfu/ml and < 0.03 EU/ml, respectively. The American Association for t ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  10. Gastrointestinal Transit Measurement System

    SBC: CREARE LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Gastrointestinal motility disorders are a significant health problem accounting for millions of physician visits each year. In many patients, measurement of gastrointestinal transit can provide important diagnostic information. However, current transit measurement techniques involve radiation and cannot make the long-duration, highly-detailed recordings needed ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
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