Award Data

Abstract For the first time it is possible to directly visualize a radiation beam hitting a patientandapos s tissue or high resolution imaging of radiation delivery in water tank phantoms using Cherenkov emission imaging This allows the opportunity to do pre treatment verification at high resolution with real time video of a test phantom prior to delivery to the patient Radiotherapy has a di ...

DESCRIPTION provided by applicant A disparity exists between rural and urban suburban children with suspected ASD in the time interval between first identification of a possible problem and a firm diagnosis This project will investigate the effect of a recently developed and validated remote diagnostic method leveraging an evidence based Smartphone Telehealth service called NODA tm for auti ...

Abstract CD CD L is a key target for immunomodulation due to its central role in controlling the activation of the immune system This well studied immune switch has been the focus of extensive drug development for over two decades The validation of this drug target consists of reproducible and robust data using rodent and NHP models of chronic inflammation autoimmune disease and organ ...

DESCRIPTION provided by applicant The lack of vaccine adjuvants that are both safe and effective is an important public health problem and is a key research priority for the NIH NIAID No adjuvants have yet been approved for use with intradermal vaccines The goal of this phase II STTR project is to move a new adjuvant for intradermal vaccination small near infrared lasers that emit brief non ...

DESCRIPTION provided by applicant Hearing loss is a leading public health concern with about of American adults reporting some degree of impairment Of those fewer than seek help for their condition for a variety of reasons To address this issue the National Institue of Deafness and Other Communication Disorders NIDCD is seeking solutions to improve hearing healthcare access and l ...

DESCRIPTION provided by applicant Anterior cruciate ligament ACL injuries are a significant problem for athletes and the prevalence has increased exponentially due to the fold increase in sports participation by women Despite demonstrated ability to decrease injury rates through the use of neuromuscular training programs the incidence of ACL injuries remains high due to poor adoption ...

DESCRIPTION (provided by applicant): With its ability to secrete high levels of recombinant proteins, the yeast Pichia pastoris is extensively used for protein manufacturing. However, as actual yields vary widely for individual proteins, GlycoFi is focusing on the improvement of protein yields in P. pastoris as part of the company's long term mission to develop yeast-based protein production tech ...

The current methodology for testing the penetration resistance of textile materials to various chemical agents has a number of drawbacks, including significant uncertainties in the resulting data, inefficiency and expense, risk to test personnel, and limited range of test conditions. The objective of the proposed work is to apply unique computer models for textiles with accompanying experimental ...

DESCRIPTION (provided by applicant): The specific aim of this project is development of a suite of novel methods to facilitate the use of CT colonography for colorectal cancer screening. Colorectal cancer, the second leading cause of cancer-related death, can be largely prevented by early identification and removal of precursor lesions. Unfortunately, compliance with colorectal cancer screening re ...

DESCRIPTION (provided by applicant): Gastrointestinal motility disorders are a significant health problem accounting for millions of physician visits each year. In many patients, measurement of gastrointestinal transit can provide important diagnostic information. However, current transit measurement techniques involve radiation and cannot make the long-duration, highly-detailed recordings needed ...