Award Data

This SBIR Phase II project will create an industrial process for bonding ceramics to metals at the molecular level. Attempts thus far have not been successful in creating robust bonds due to incongruities of the materials being bonded. The objective of this project is to develop a sophisticated, computer controlled, automated bonding machine that will rapidly and safely impact-bond net-shaped cera ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project has the potential to help enhance disease resistance in poultry and increase yields due to the delivery of only healthy, fully vaccinated chicks to farms. These healthier chicks will reduce the need for antibiotics in poultry, aiding to combat antimicrobial resistance. This technology has imm ...

GeneCapture, Inc. is proposing to develop a rapid in vitro diagnostic prototype using our patented molecular-based CAPTURE (ConfirmActive Pathogens Through Unamplified RNA Expression) assay. Based on the results and experience gained in our Phase I STTR contractHDTRA1-16C-0061: Infectious Disease Diagnostics and Differentiation of Viral vs. Bacterial Infections for Point of Care Applications, we p ...

Interfaces on existing military chemical/biological protection garments are not designed to fully eliminate macroscopic and microscopic air gaps at folds, fabric surfaces, or hook-and-loop closures, and thus do not provide a hermetic barrier against exposure. Creare is developing hermetic garment closure systems that seal macroscopic and microscopic gaps at interfaces and closures and provide high ...

The skin is the first line of defense against chemical warfare agents including nerve agents and toxic industrial chemicals, providing a possible barrier or delay to systemic distribution. Some chemicals also can act directly on the skin including the vesicants sulfur mustard and lewisite. Early and rapid skin decontamination is extremely important following exposure to CWAs and TICs because it de ...

DNA microarray technology, in combination with statistical and predictive modeling tools, could be used to evaluate thousands of genes against distinct gene expression patterns induced by chemical/biological agents to provide early identification and speed therapeutic intervention. The overall objective of this Phase II effort is to leverage existing public domain resources and commercial tools t ...

This Small Business Innovation Research (SBIR) Phase II project integrates the imaging system developed in Phase I with a smart-sensor injection system that can inject or sample from the cavity underlying the early chicken embryo with high levels of accuracy accompanied with improved hatch when compared to manual methods. The Phase I work showed that it was possible to image and detect the blasto ...

This Small Business Innovation Research Phase II project deals with the problems of reconstructing complex free-form shapes from measured data. Raindrop Magic's primary interest is to produce well-structured, high-quality CAD models. Several techniques exist to reach this goal; unfortunately, automatic surfacing systems provide only rough approximations and do not capture the original design int ...

This Small Business Innovation Research (SBIR) Phase II project will investigate applications of Combinatorial Morse Theory in Reverse Engineering, a field that focuses on converting physical objects into a digital representation suitable for CAD, CAM, and CAE. The biggest challenge in this field is to automate the conversion process while producing a model that meets all the requirements of downs ...

This Small Business Innovation Research (SBIR) Phase II project is to develop a fully functional prototype 3-D laparoscope, which will be superior to the 2-D laparoscopes currently used in surgeries, based on laser illuminated miniaturized projector for computer generated light patterns and two cameras for acquisition of color and depth. The commercial application of this project will be in surgi ...