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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.
SBC: CFD Research Corporation Topic: CBD10103
Current drug discovery and development efforts are severely limited by expensive animal trials and oversimplified in vitro models. Results obtained from in vitro models are not predictive of in vivo toxicity owing to significant difference from the in vivo physiological conditions. In this context, we propose to develop and demonstrate a novel microfluidic device that reproduces the physiological ...SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
SBC: KLEIN ASSOC., INC. Topic: N/A
SIDE SCAN SONAR HAS DEVELOPED TO THE POINT WHERE IT IS NOW AN ACCEPTED PART OF HYDROGRAPHIC CHARTING PROJECTS, AS WELL AS A BROAD RANGE OF OCEAN SEARCH AND SURVEY APPLICATIONS. ONE LIMITATION ON ITS UTILITY, HOWEVER, IS THE REQUIREMENT TO OPERATE THE SYSTEM AT RELATIVELY LOW SPEEDS (5 KNOTS OR LOR LESS) IN ORDER TO ACQUIRE HIGH-QUALITY DATA. ANY INCREASEIN VESSEL SPEED CAPABILITY WOULD RESULT IN G ...SBIR Phase II 1987 Department of Commerce
SBC: CFD Research Corporation Topic: CBD10107
Current high-throughput platforms rely on labeled substrates that produce detectable spectroscopic signals upon reaction for monitoring enzyme catalytic activity. Add to that the high price tag for these instruments, ranging from several hundred thousand to millions of dollars, and there is a clear need for alternate solutions for a label-free, low-cost, high-throughput enzyme screening platform. ...SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense