Award Data

Current drug discovery and development efforts are severely limited by expensive animal trials and oversimplified in vitro models. Results obtained from in vitro models are not predictive of in vivo toxicity owing to significant difference from the in vivo physiological conditions. In this context, we propose to develop and demonstrate a novel microfluidic device that reproduces the physiological ...

Current high-throughput platforms rely on labeled substrates that produce detectable spectroscopic signals upon reaction for monitoring enzyme catalytic activity. Add to that the high price tag for these instruments, ranging from several hundred thousand to millions of dollars, and there is a clear need for alternate solutions for a label-free, low-cost, high-throughput enzyme screening platform. ...

DARPA is interested in advanced UV laser technology for development of miniature UV 3D LIDARs. UV sources are preferred for seeing through many natural and man made obscurants. Princeton Optronics proposes to develop a miniature UV source at wavelength below 300nm by pumping a solid state laser gain medium with VCSEL array and frequency convert the laser beam to UV frequency. With this approach ...

ALGORITHMS BASED ON NONLINEAR FREQUENCY ANALYSIS OFFER THE POTENTIAL FOR A NEW GENERATION OF MORE POWERFUL SURVEILLANCE ALGORITHMS. THE FUNDAMENTAL ARCHITECTURES FOR THEIR COMPUTER IMPLEMENTATION ARE THE SUBJECT OF THIS STUDY.

Surface plasmons (SPs) have been studied by a wide spectrum of scientists, ranging from physicists, chemists and materials scientists to biologists. Plasmonics represents an opportunity to develop a new class of photonic devices by concentrating and channeling light using subwavelength structures. Such circuits would first convert light into SPs, which would then propagate and be processed by lo ...

The demand for renewable energy is motivating R & D efforts toward the development of novel photovoltaic (PV) technology. Efficient and low cost solar cells will have an important role in defense applications particularly powering portable electronic de-vices. Current solar cells based on single crystal silicon are still not at a level to be cost effective when compared to other forms of electrica ...