Award Data

The vast majority of injuries in recent military conflicts have been inflicted by improvised explosive devices (IEDs) causing brain, extremities and genital-urinary injuries. Advanced computational models of IED blast physics and human body injury biomech

Many emergency cricothyrotomy kits have been developed in an attempt to simplify this potentially life-saving medical procedure. However, none of the existing kits perform noticeably better than the standard surgical kit. The standard kit itself has led

The objective of this project is to develop, produce, and commercialize a liquid-tight, field-applicable, ocular patch for wound stabilization and treatment of the eye following a war-related injury to the ocular surface. The patch consists of a curved flexible silicone membrane (similar in size and shape to a contact lens) which has had (1) a novel bio-adhesive

Currently, no commercial products exist for the repair of large injuries to muscle, particularly volumetric muscle loss (VML). In Phase I of this project, data demonstrated that keratin biomaterials can provide temporal release of growth factors while maintaining cell viability in vitro and in vivo. In Phase II, the biomaterial formulation was optimized for spatio-temporal delivery of cells and gr ...

Current methods for stem cell isolation are time-consuming, costly, and labor-intensive, and ill-suited for point of care applications. To overcome these limitations, we propose to develop and demonstrate a high-throughput, non-invasive, microfluidic stem cell analyzer to enable a rapid isolation of high-quality stem cell products from clinically relevant samples. Our technology enables significan ...

The overall objective of the proposed project is to develop new injury criteria, model based risk assessment methodology, and a software tool to assess neck injury risk from head supported mass (HSM) loading. Based on the foundation of Phase I feasibility studies, the proposed Phase II work will focus on model enhancement, extension and validation, risk assessment, and software integration and tes ...

Musculoskeletal injury among military personnel is an under-recognized problem where shoulder injuries are significant and result in inflammation and pain from overuse, joint derangement, sprain/stain/rupture, and dislocation. Health hazard assessment is essential to ensure that fielded equipment and occupational duties do not exceed human capabilities over short and long term exposures. Hazard ...

Burn injuries, particularly those to the face, present a number of functional and psychological challenges that arise from scarring and related contracture. A major goal of trauma and burn surgeons is to prevent scarring and improve grafting technologies given the complexity of facial topography. This project seeks to optimize and finalize a prototype of a 3D printed keratin facemask capable of ...

Combat surgery training is an essential mission of the US Armed Forces. Courses such as Emergency War Surgery Course (EWSC) and Advanced Trauma Operative Management (ATOM) have been developed to meet this requirement. However, these courses do not cover all relevant procedures and rely on animals and cadavers which limits their utility. Operative Experience Incorporated will further improve the tr ...

In the initial SBIR Phase II, Intelligent Automation, Inc. (IAI) developed a voice-based Tele-PTSD Monitor (TPM) system to remotely screen, monitor, and provide assistance to clinicians in assessing a PTSD patients condition. ListEn is the brain of TPM system. It processes the voice data, extracts different types of salient features, and computes PTSD scores based on state-of-art machine learning ...