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The Award database is continually updated throughout the year. As a result, data for FY21 is not expected to be complete until September, 2022.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. THE SUSPENSION CORE DRILL

    SBC: Browning Engineering            Topic: N/A

    CONVENTIONAL ROCK CORE DRILLING AT GREAT DEPTHS IS EXTREMELY EXPENSIVE AND TIME CONSUMING. ITS MAJOR DRAWBACK IS THE REQUIRED LENGTH OF DRILL PIPE. THE SUSPENSION CORE DRILL IS SUPPORTED BY CONTINUOUS FLEXIBLE LEADS HELD ON ONE OR MORE HIGH-SPEED REELS. WITHDRAWALS AND REPLACEMENT TIMES CAN BE REDUCED BY AN ORDER-OF-MAGNITUDE. COMMERCIAL USES INCLUDE STANDARD CORING APPLICATIONS AS WELL AS INTERMI ...

    SBIR Phase II 1987 National Science Foundation
  2. STUDY OF SHOCK WAVE PROPAGATION AND PHASED-ARRAY FOCUSING FOR LITHOTRIPSY

    SBC: Applied Research Associates, Inc.            Topic: N/A

    THIS PHASE I EFFORT WILL APPLY THEORETICAL METHODS BASED PRINCIPALLY ON CAGNIARD'S FORMALISM (PREVIOUSLY INCORPORATED BY US INTO OUR POWERFUL SWREF CODE), TO THE PROPAGATION AND FOCUSING, IN BOTH REFLECTIVE AND PHASED-ARRAY EQUIPMENT, OF SHOCK-WAVES PRODUCED BY UNDERWATER SPARKS. THE OBJECTIVE IS TO INVESTIGATE AND PROVIDE DESIGN DATA FOR LITHOTRIPSY EQUIPMENT IN WHICH FOCUSED SHOCK WAVES ARE USED ...

    SBIR Phase II 1987 National Science Foundation
  3. SBIR Phase II: NIFUT Technology for recycling fluorides from Uranium Tetrafluoride

    SBC: Pearlhill Technologies, LLC            Topic: PhaseII

    This Small Business Innovation Research (SBIR) Phase II project proposes to significantly expand the number of marketable compounds that can be converted from depleted uranium tetrafluoride (DUF4). DUF4 is produced by the reduction of depleted hexafluoride (DUF6), the largest and one of the most toxic waste components of the entire nuclear fuel cycle. Current technology can convert DUF4 into metal ...

    SBIR Phase II 2011 National Science Foundation
  4. Microfluidic High-throughput Platform for Determining Kinetic Constants of Enzyme Variants

    SBC: CFD Research Corporation            Topic: CBD10107

    Current high-throughput platforms rely on labeled substrates that produce detectable spectroscopic signals upon reaction for monitoring enzyme catalytic activity. Add to that the high price tag for these instruments, ranging from several hundred thousand to millions of dollars, and there is a clear need for alternate solutions for a label-free, low-cost, high-throughput enzyme screening platform. ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  5. MATHEMATICAL MODELING OF MAMMALIAN CELLS

    SBC: Verax Corp            Topic: N/A

    THE RECENT DEVELOPMENT OF MOLECULAR BIOLOGY, PARTICULARLY INTHE FIELD OF RECOMBINANT DNA TECHNOLOGY, GIVES BIRTH TO A NEW ERA IN MEDICAL THERAPEUTICS AND DIAGNOSTICS USING PRODUCTS FROM MAMMALIAN CELL CULTURE. FOR EFFECTIVE RESEARCH AND CLINICAL USE, THESE PRODUCTS NEED TO BE MANUFACTURED IN LARGE QUANTITIES AND AT A TOLERABLE COST. TODAY PRODUCTION COSTS ARE VERY HIGH. THIS PROPOSAL IS PARTOF AN ...

    SBIR Phase II 1987 National Science Foundation
  6. Development of an extremely efficient nebulizer for intranasal vaccination

    SBC: CREARE LLC            Topic: N/A

    Extremely Efficient Nebulizer for Intranasal Vaccination. Specifically the nasal delivery device could reduce health care associated infections by providing a needle-free method of delivery of vaccines and therapeutics which are currently delivered by injection with all the attendant risks of transmission of blood borne disease through needle-stick injury and unsafe needle practices. One of the m ...

    SBIR Phase II 2011 Department of Health and Human ServicesCenters for Disease Control and Prevention
  7. A Novel Microfludic Device for Drug Toxicity Studies

    SBC: CFD Research Corporation            Topic: CBD10103

    Current drug discovery and development efforts are severely limited by expensive animal trials and oversimplified in vitro models. Results obtained from in vitro models are not predictive of in vivo toxicity owing to significant difference from the in vivo physiological conditions. In this context, we propose to develop and demonstrate a novel microfluidic device that reproduces the physiological ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  8. ACTIVELY CONTROLLED GAS BEARINGS

    SBC: Burton Technologies Inc            Topic: N/A

    RESEARCH AND DEVELOPMENT WILL BE CARRIED OUT TO PROVIDE PROTOTYPE, ACTIVELY CONTROLLED GAS BEARINGS FOR PRECISION MOVEMENT IN INSTRUMENTS AND MACHINE TOOLS. THIS WILL DRAW UPON PRELIMINARY WORK ON (1) FABRICATION, (2) DYNAMIC ANALYSIS OF THE BEARING AND SUPPORTED MASS, (3) PIEZOELECTRIC VALVING AND PIEZOELECTRIC DISPLACEMENT OF THE BEARING SURFACE, AND (4) THE ADAPTATION OF A MICROPROCESSOR TO SER ...

    SBIR Phase II 1987 National Science Foundation
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