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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Smartphone Application for Mask Sizing and Projecting Quantitative Fit

    SBC: CFD RESEARCH CORPORATION            Topic: CBD161005

    Typical procedures for respirator masks sizing and protective fit test are time-consuming and user intensive, requiring taking anthropometricmeasurements of the wearer, sampling the wearers breathing zone and the use of specialized tools and equipment. The proposed softwareapp aims to quickly, accurately and automatically perform respirator mask sizing and predict protective fit using only 2D imag ...

    SBIR Phase II 2017 Department of DefenseOffice for Chemical and Biological Defense
  2. Signal Processing for Layered Sensing

    SBC: VADUM INC            Topic: CBD152006

    Vadum will develop Chemical, Heterogeneous sensor fusion Incident awareness Module (CHIME)asoftware module that will ingest data from a large number of asynchronous, heterogeneous and multi-tiered sensors to automate the process of estimating the source attributes of a chemical or biological release. CHIME generates estimates from a continuous stream of raw sensor data with successive estimates al ...

    SBIR Phase II 2017 Department of DefenseOffice for Chemical and Biological Defense
  3. Producing Novel Biosynthetic Therapeutics from Extreme Microbiomes

    SBC: iXpressGenes, Inc.            Topic: CBD152004

    This project is a unique metagenomic evaluation of under-studied extremophilic microbiome natural products (NPs), with the goal of discovering novel antibiotic biowarfare agent (BWA) countermeasures. A metagenomic biosynthetic gene cluster library from extremophilic sources was created, sequenced, analyzed, and exploited to produce several broad-spectrum antibiotic extracts during the Phase I effo ...

    SBIR Phase II 2017 Department of DefenseOffice for Chemical and Biological Defense
  4. Microfluidic High-throughput Platform for Determining Kinetic Constants of Enzyme Variants

    SBC: CFD RESEARCH CORPORATION            Topic: CBD10107

    Current high-throughput platforms rely on labeled substrates that produce detectable spectroscopic signals upon reaction for monitoring enzyme catalytic activity. Add to that the high price tag for these instruments, ranging from several hundred thousand to millions of dollars, and there is a clear need for alternate solutions for a label-free, low-cost, high-throughput enzyme screening platform. ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  5. Focal Plane Array Technology for Passive Hyperspectral Standoff Detection

    SBC: EPIR TECHNOLOGIES INC            Topic: CBD10105

    Chemical imaging sensors require focal plane arrays (FPAs) incorporating long wavelength infrared (LWIR) detectors suitable for hyperspectral detection. These detectors require high sensitivity to account for the low photon counts in narrow wavelength bands. The required sensitivity elevates the associated costs, so a need exists for a lower cost LWIR FPA for use with chemical imaging sensors. The ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  6. Exploiting Natural Products-Based Therapeutics for Aflatoxin Mitigation

    SBC: CFD RESEARCH CORPORATION            Topic: CBD152003

    Aflatoxins B1 (AFB1) are fungal produced mycotoxins that are present in food supplies and are strongly associated with increased risk for thedevelopment of hepatocellular carcinoma. Currently, there are no known countermeasures to selectively mitigate AFB1 toxicity. To meet thischallenge, we successfully validated a Phase I proof-of-concept study to harness the microbiome extracts of scavenging ma ...

    SBIR Phase II 2017 Department of DefenseOffice for Chemical and Biological Defense
  7. Development of an extremely efficient nebulizer for intranasal vaccination

    SBC: CREARE LLC            Topic: N/A

    Extremely Efficient Nebulizer for Intranasal Vaccination. Specifically the nasal delivery device could reduce health care associated infections by providing a needle-free method of delivery of vaccines and therapeutics which are currently delivered by injection with all the attendant risks of transmission of blood borne disease through needle-stick injury and unsafe needle practices. One of the m ...

    SBIR Phase II 2011 Department of Health and Human ServicesCenters for Disease Control and Prevention
  8. A Novel Microfludic Device for Drug Toxicity Studies

    SBC: CFD RESEARCH CORPORATION            Topic: CBD10103

    Current drug discovery and development efforts are severely limited by expensive animal trials and oversimplified in vitro models. Results obtained from in vitro models are not predictive of in vivo toxicity owing to significant difference from the in vivo physiological conditions. In this context, we propose to develop and demonstrate a novel microfluidic device that reproduces the physiological ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
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