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The Award database is continually updated throughout the year. As a result, data for FY21 is not expected to be complete until September, 2022.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. A Low-SWap Powered Air Purifying Respirator (PAPR)

    SBC: CREARE LLC            Topic: CBD181002

    The proposed low-SWaP PAPR technology improves the convenience, comfort, and protection level for respirators used in low-threat hazardous environments. Creare’s PAPR technology will be applicable to a variety of respiratory protection needs, including emergency escape, laboratory and field work in low-hazard conditions, and some combat and combat support activities. The PAPR will improve user f ...

    SBIR Phase II 2020 Department of DefenseOffice for Chemical and Biological Defense
  2. A Novel Microfludic Device for Drug Toxicity Studies

    SBC: CFD Research Corporation            Topic: CBD10103

    Current drug discovery and development efforts are severely limited by expensive animal trials and oversimplified in vitro models. Results obtained from in vitro models are not predictive of in vivo toxicity owing to significant difference from the in vivo physiological conditions. In this context, we propose to develop and demonstrate a novel microfluidic device that reproduces the physiological ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  3. 3D Printed Manufacturing of Respiratory Protection

    SBC: AKITA INNOVATIONS LLC            Topic: CBD181001

    The principal benefit of this project will be the development of materials, processes and designs for the additive manufacture of air purifying respirators. Additive manufacture allows mass personalization of existing systems. For respirators, that design is the unique size and facial structure of each individual warfighter. The ability to personalize respirator design to each unique warfighter wi ...

    SBIR Phase II 2020 Department of DefenseOffice for Chemical and Biological Defense
  4. Dual Formulation of Atropine/Scopolamine with Enhanced Stability

    SBC: Nano Terra, Inc.            Topic: CBD181005

    The standard US military treatment for nerve agent exposure is application of up to three autoinjectors, each containing atropine sulfate and 2-pralidoxime, to counteract symptoms of nerve agent intoxication and restore acetylcholinesterase activity. This treatment increases survival rates after nerve agent exposure, however, seizures resulting from nerve agent poisoning are a common symptom that ...

    SBIR Phase II 2020 Department of DefenseOffice for Chemical and Biological Defense
  5. Durable Stretch Barrier Materials

    SBC: LaunchBay LLC            Topic: CBD181003

    Chemical, Biological, Radioactive and Nuclear (CBRN) protective ensembles are widely used by the US Military and civilian first responders as the first line of defense for personnel working in contaminated environments. Many innovative products have been developed for the chemical protective clothing market in response to demand from the market place for improved performance. However, the need for ...

    SBIR Phase II 2020 Department of DefenseOffice for Chemical and Biological Defense
  6. Low noise longwave infrared (8-12µm) focal plane array with high sensitivity for passive hyperspectral standoff detection

    SBC: APPLIED NANOFEMTO TECHNOLOGIES LLC            Topic: CBD10105

    Longwave infrared (LWIR, 8-12µm) focal plane arrays (FPAs) play an important role in hyperspectral chemical and biological (CB) sensing and spectral imaging. Existing thermal detectors are unable to meet the high sensitivity and fast response requirements of many hyperspectral chemical and biological sensing applications. FPAs based on photon excited electron generation process can fulfill the sp ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  7. MEMS Lamellar Based Interferometer for the Detection of Toxic Chemicals

    SBC: AGILTRON, INC.            Topic: CBD10104

    Leveraging on Agiltron industry leading development of optical MEMS devices and the PI experience with FTIR spectrometer design, we propose to develop a new class of high performance compact and rugged FTIR spectrometers for the LWIR optical range. The design is based on the MEMS lamellar mirror technique. Although this approach is not new, it has not yet been efficiently applied to LWIR, and per ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  8. Microfluidic High-throughput Platform for Determining Kinetic Constants of Enzyme Variants

    SBC: CFD Research Corporation            Topic: CBD10107

    Current high-throughput platforms rely on labeled substrates that produce detectable spectroscopic signals upon reaction for monitoring enzyme catalytic activity. Add to that the high price tag for these instruments, ranging from several hundred thousand to millions of dollars, and there is a clear need for alternate solutions for a label-free, low-cost, high-throughput enzyme screening platform. ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  9. MicroLens Hyperspectral Imager for Standoff Chemical Detection

    SBC: Bodkin Design & Engineering, LLC            Topic: CBD171002

    The research resulted in the development of a new approach to hyperspectral imaging utilizing Compressive Sensing. The newly conceived snapshot spectral imager will provide spectral data in a very compact package. It will be virtually indistinguishable from a standard infrared camera but with the added capability for spectral measurement. The camera will thus deliver chemical species information m ...

    SBIR Phase II 2020 Department of DefenseOffice for Chemical and Biological Defense
  10. Novel Circulating RNA-based Markers as Diagnostic Biomarkers of Infectious Diseases

    SBC: CFD Research Corporation            Topic: CBD18A001

    In resource limited settings, rapid and accurate diagnosis of infections is critical for managing potential exposures to highly virulent pathogens, whether occurring from an act of bioterrorism or a natural event. This is especially important for hard to detect intracellular bacterial and alphavirus infections, that overlap symptomatically and often treated empirically due to a lack of reliable an ...

    STTR Phase II 2020 Department of DefenseOffice for Chemical and Biological Defense
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