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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY21 is not expected to be complete until September, 2022.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. A Cryogenic Grinding System for the High Productivity Grinding of Advanced Materials

    SBC: CREARE LLC            Topic: DLA09001

    High performance metals, ceramics, and hard coatings are used in military applications to enhance the performance of key systems needed by the warfighter. One of the most prevalent operations to remove material, achieve the desired surface finish, or enhance part quality is bulk and finish grinding. For typical cutting speeds, conventional synthetic or oil-based coolants are sufficient to remove ...

    SBIR Phase II 2011 Department of DefenseDefense Logistics Agency
  2. A Novel Microfludic Device for Drug Toxicity Studies

    SBC: CFD Research Corporation            Topic: CBD10103

    Current drug discovery and development efforts are severely limited by expensive animal trials and oversimplified in vitro models. Results obtained from in vitro models are not predictive of in vivo toxicity owing to significant difference from the in vivo physiological conditions. In this context, we propose to develop and demonstrate a novel microfluidic device that reproduces the physiological ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  3. Botulinum Toxin Plantibodies

    SBC: Planet Biotechnology Incorporated            Topic: CBD03103

    The primary goals of this Phase II application are to successfully manufacture pilot-scale quantities of neutralizing anti-botulinum toxin antibodies in plants, and to complete preclinical studies with these antibodies. Our collaborator, Dr. James D. Mar

    SBIR Phase II 2004 Department of DefenseOffice for Chemical and Biological Defense
  4. Carbon Based Nano-Additives for Chemically and Biologically Protective Polymeric Nanocomposites

    SBC: ATS-MER, LLC            Topic: CBD03304

    The development of carbon-based nano-additive bound polymers with enhanced adsorption capacity and reactivity for the neutralization of chemical and biological warfare agents could cause substantial saving of life during CBWA threats. In the Phase I pr

    SBIR Phase II 2004 Department of DefenseOffice for Chemical and Biological Defense
  5. 3D Microfluidic Platform for in vitro Hematopoietic Stem Cell (HSC) Culture

    SBC: Physical Optics Corporation            Topic: CBD10103

    Poor drug candidates are often identified late in the drug development process (e.g., in the preclinical and clinical phases) and contribute significantly to the high cost and low yield of drug discovery. As a result, new tools are needed to accelerate the assessment of drug candidate toxicity earlier in the drug development process. To address this Chemical/Bio Defense (CBD) need, Physical Optics ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  6. Microfluidic High-throughput Platform for Determining Kinetic Constants of Enzyme Variants

    SBC: CFD Research Corporation            Topic: CBD10107

    Current high-throughput platforms rely on labeled substrates that produce detectable spectroscopic signals upon reaction for monitoring enzyme catalytic activity. Add to that the high price tag for these instruments, ranging from several hundred thousand to millions of dollars, and there is a clear need for alternate solutions for a label-free, low-cost, high-throughput enzyme screening platform. ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  7. Miniature Residual Life Indicator

    SBC: Physical Optics Corporation            Topic: CBD10106

    To address the Chemical and Biological Defense (CBD) need for a residual life indicator (RLI) capable of determining the degradation in physical adsorption and reactive capacity arising from battlefield contaminants and exposure to the elements, Physical Optics Corporation (POC) proposes to continue the development of a new Miniature Residual Life Indicator (MRLIN). MRLIN is based on impedance spe ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  8. MOEMS Miniaturized Real-time Visible/UV Spectrometer

    SBC: MORGAN RESEARCH CORP.            Topic: CBD02300

    This Phase II SBIR proposal is for the development of a miniaturized real-time visible/UV spectrometer prototype based on micro-opto-electro-mechanical systems (MOEMS) technology. Use of MOEMS technology enables orders of magnitude reductions in size, we

    SBIR Phase II 2004 Department of DefenseOffice for Chemical and Biological Defense
  9. Multifunctional Antisense Therapeutics Nanocarrier and Inhalation Device

    SBC: Physical Optics Corporation            Topic: CBD10102

    To address the CBD need for improved formulations to enhance the ease of use and bioavailability of antisense therapeutics, Physical Optics Corporation (POC) proposes to advance development of a Multifunctional Antisense Therapeutics Nanocarrier and Inhalation Device (MATEN). This proposed system is based on a new dry powder formulation and a novel design of an inhaler that uses mature components ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  10. Next Generation Integrated Electrophoretic Nanofluidic Biochip Sensor Platform for the THz Spectroscopic Finger Printing of Biological Species and Age

    SBC: REDONDO OPTICS            Topic: CBD10110

    Redondo Optics Inc. (ROI), proposes to develop and demonstrate a next generation integrated electrophoretic nanofluidic biochip (INTRay-Nanochip) sensor platform for the"label-less"THz spectroscopy finger printing of biological species and agents. In the proposed Phase II of this program, ROI will focus on the engineering development of a manufacturable optical nanolithography technology to enable ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
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