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The Award database is continually updated throughout the year. As a result, data for FY21 is not expected to be complete until September, 2022.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. A Miniature Autoinjector for Multicomponent Drugs and Vaccines

    SBC: CREARE LLC            Topic: CBD13106

    Chemical, biological, or toxin attacks in military and civilian settings are a serious and growing concern. Standard first aid for exposure to some chemical warfare agents and toxins includes the immediate administration of relevant antidotes using an autoinjector. When an attack occurs, pre-filled autoinjectors must be immediately available and thus highly portable, and they must be suitable fo ...

    SBIR Phase II 2014 Department of DefenseOffice for Chemical and Biological Defense
  2. An automated, high throughput, resin-free device for large scale protein purification

    SBC: CFD Research Corporation            Topic: CBD12102

    Protein manufacturing is of paramount importance to chemical and biological defense applications. Existing protein purification methods primarily rely on synthetic-resin based chromatography, which is time-consuming, labor-intensive, expensive, and consequently, ill-suited for developing rapid countermeasures to chemical and biological threats. To overcome these limitations, the overall goal of th ...

    SBIR Phase II 2014 Department of DefenseOffice for Chemical and Biological Defense
  3. A Novel, Aerodynamics-augmented Continuous Ionization System for Electrostatic Collection of Bioaerosols

    SBC: CFD Research Corporation            Topic: CBD12107

    Safe and efficient ionization and filtration technology compatible to biodefense applications is of paramount importance. Current ionization methods are energy-intensive, costly, prone to ozone generation, or inefficient, and consequently ill-suited for building protection applications. To overcome these limitations, we propose to develop and demonstrate a novel bioaerosol ionization and collectio ...

    SBIR Phase II 2014 Department of DefenseOffice for Chemical and Biological Defense
  4. A Novel Microfludic Device for Drug Toxicity Studies

    SBC: CFD Research Corporation            Topic: CBD10103

    Current drug discovery and development efforts are severely limited by expensive animal trials and oversimplified in vitro models. Results obtained from in vitro models are not predictive of in vivo toxicity owing to significant difference from the in vivo physiological conditions. In this context, we propose to develop and demonstrate a novel microfluidic device that reproduces the physiological ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  5. Carbon Based Nano-Additives for Chemically and Biologically Protective Polymeric Nanocomposites

    SBC: ATS-MER, LLC            Topic: CBD03304

    The development of carbon-based nano-additive bound polymers with enhanced adsorption capacity and reactivity for the neutralization of chemical and biological warfare agents could cause substantial saving of life during CBWA threats. In the Phase I pr

    SBIR Phase II 2004 Department of DefenseOffice for Chemical and Biological Defense
  6. Hermetic Seals for Chemical/Biological Protective Garments

    SBC: CREARE LLC            Topic: CBD13109

    Interfaces on existing military chemical/biological protection garments are not designed to fully eliminate macroscopic and microscopic air gaps at folds, fabric surfaces, or hook-and-loop closures, and thus do not provide a hermetic barrier against exposure. Creare proposes to develop a hermetic garment closure system that seals macroscopic and microscopic gaps at interfaces and closures and pro ...

    SBIR Phase II 2014 Department of DefenseOffice for Chemical and Biological Defense
  7. Microfluidic High-throughput Platform for Determining Kinetic Constants of Enzyme Variants

    SBC: CFD Research Corporation            Topic: CBD10107

    Current high-throughput platforms rely on labeled substrates that produce detectable spectroscopic signals upon reaction for monitoring enzyme catalytic activity. Add to that the high price tag for these instruments, ranging from several hundred thousand to millions of dollars, and there is a clear need for alternate solutions for a label-free, low-cost, high-throughput enzyme screening platform. ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  8. MOEMS Miniaturized Real-time Visible/UV Spectrometer

    SBC: MORGAN RESEARCH CORP.            Topic: CBD02300

    This Phase II SBIR proposal is for the development of a miniaturized real-time visible/UV spectrometer prototype based on micro-opto-electro-mechanical systems (MOEMS) technology. Use of MOEMS technology enables orders of magnitude reductions in size, we

    SBIR Phase II 2004 Department of DefenseOffice for Chemical and Biological Defense
  9. Regenerable, heat-Abating, humidity-Neutralizing, Carbon diOxide Removal System (RANCOR) Phase II

    SBC: Paragon Space Development Corporation            Topic: CBD12106

    In Phase I RANCOR successfully demonstrated an innovative enabling humidity control technology to provide very low humidity air to water sensitive, fully reusable CO2 adsorbents. The use of adsorbents enables complete reusability/rechargability and reduces the total heat load on the SCBA to the point where ice or other cooling systems will no longer be required. In Phase II Paragon will introduce ...

    SBIR Phase II 2014 Department of DefenseOffice for Chemical and Biological Defense
  10. Sensitive Molecular Beacons (MB) Based DNA Microarray

    SBC: BIOMACHINES, INC.            Topic: CBD02101

    In the wake of the September 11th attacks and subsequent Anthrax scares, researchers worldwide are working to expand our ability to rapidly assess what poses a terrorism threat to the public. The rapid detection of specific pathogens is required for biod

    SBIR Phase II 2004 Department of DefenseOffice for Chemical and Biological Defense
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