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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY21 is not expected to be complete until September, 2022.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. A Novel Microfludic Device for Drug Toxicity Studies

    SBC: CFD Research Corporation            Topic: CBD10103

    Current drug discovery and development efforts are severely limited by expensive animal trials and oversimplified in vitro models. Results obtained from in vitro models are not predictive of in vivo toxicity owing to significant difference from the in vivo physiological conditions. In this context, we propose to develop and demonstrate a novel microfluidic device that reproduces the physiological ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  2. Characterization and Mitigation of Radiation Effects in Nonplanar Nano-technology Microelectronics

    SBC: CFD Research Corporation            Topic: DTRA092001

    Future high-performance integrated circuits in DoD satellite systems will require silicon-on-insulator (SOI) and non-planar nano-technology devices, such as MultiGate Field Effect Transistors (MuGFETs) or FinFETs, which can decrease pattern area of logic circuits below 50% of the conventional planar technologies. However, the single-event-effect (SEE) response of non-planar devices and circuits is ...

    SBIR Phase II 2011 Department of DefenseDefense Threat Reduction Agency
  3. Critical Data Processing for Chemical Warfare Simulant Field Testing – Advanced Data Fusion

    SBC: Torch Technologies, Inc.            Topic: CBD05110

    In this Phase II SBIR project for the Army CBD, Torch Technologies of Huntsville, AL, will develop and demonstrate a fully operational prototype of its Advanced Chemical Release Evaluation System for fusing measurements of the concentration of clouds resulting from chemical releases. The ability to evaluate the performance of a stand-off detector during development depends on the ability to accura ...

    SBIR Phase II 2006 Department of DefenseOffice for Chemical and Biological Defense
  4. Filovirus drug discovery using novel combinations of approved drugs

    SBC: APATH, LLC            Topic: CBD05119

    The goal of this proposal is to find novel combinations of approved drugs for the treatment and/or prevention of infection with filoviruses. Ebola and Marburg viruses, the only filoviruses, cause an acute hemorrhagic fever syndrome which has a high mortality rate and poses a significant bio-terrorism threat. There are currently no therapeutic agents available to treat filovirus infections and the ...

    SBIR Phase II 2006 Department of DefenseOffice for Chemical and Biological Defense
  5. Handheld FT-IR/Photoacoustic Chemical Agent Detector

    SBC: MANNING APPLIED TECHNOLOGY            Topic: CBD05112

    Manning Applied Technology proposes development of the MP-100 handheld FT-infrared photoacoustic chemical agent detector, following a highly successful Phase I effort. Chemical attacks and accidents can be mitigated partially by cost-effective sensors. High priority programs will benefit from a sensor compliant to Joint Warning & Reporting Network (JWARN) standards. The device is ideally suited to ...

    SBIR Phase II 2006 Department of DefenseOffice for Chemical and Biological Defense
  6. Improved High-Fidelity Forecasting Capability using Combined Mesoscale and Microscale Models

    SBC: CFD Research Corporation            Topic: DTRA04002

    We propose to improve the accuracy and capability of Numerical Weather Prediction (NWP) and Atmospheric Transport and Dispersion (ATD) models by performing a tight, downscale/upscale coupling of a community NWP forecasting system, WRF, with a special purpose, urban-to-microscale Computational Fluid Dynamics (CFD) model. This new capability addresses “bridging the gap” between the mesoscale and ...

    SBIR Phase II 2006 Department of DefenseDefense Threat Reduction Agency
  7. Improved Mixed-Mode Simulation Tools for Radiation Hardening of Nanoscale Semiconductor Integrated Circuits

    SBC: CFD Research Corporation            Topic: DTRA05001

    Strategic DoD satellite and missile systems (Space Based Radar, Space Tracking Surveillance Systems) operate in harsh radiation environments, and will be increasingly based on novel sub-100-nm semiconductor technologies and highly complex circuits. To ensure interruption-free operation, accurate prediction of the radiation response of these technologies and circuits is critical. Predictive calcula ...

    SBIR Phase II 2006 Department of DefenseDefense Threat Reduction Agency
  8. Microfluidic High-throughput Platform for Determining Kinetic Constants of Enzyme Variants

    SBC: CFD Research Corporation            Topic: CBD10107

    Current high-throughput platforms rely on labeled substrates that produce detectable spectroscopic signals upon reaction for monitoring enzyme catalytic activity. Add to that the high price tag for these instruments, ranging from several hundred thousand to millions of dollars, and there is a clear need for alternate solutions for a label-free, low-cost, high-throughput enzyme screening platform. ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  9. Real-time, Three-dimensional, Visualization Software for Current and Next Generation Consequence Assessment Models

    SBC: CFD Research Corporation            Topic: DTRA04006

    We propose to develop a forward-deployable, three-dimensional visualization capability suitable for incorporation into web-based, next-generation consequence assessment models, such as the Joint Effects Model (JEM) and the Integrated Weapons of Mass Destruction Toolset (IWMDT). The thin-interface, web-based, image-server visualization model will enable more informed decisions by the consequence as ...

    SBIR Phase II 2006 Department of DefenseDefense Threat Reduction Agency
  10. Weapon Payloads for Bulk Chemical and Biological Agent Neutralization

    SBC: Integrated Solutions for Systems, Inc.            Topic: DTRA092012

    Current offensive solutions to neutralize chem/bio agent facilities rely on blast and/or short-burst high-temperature neutralization but have the potential to produce severe collateral damage via agent release. Our team proposes the Dispersed Energetics Coupled for Optimized Neutralization (DECON) Concept, an alternative concept to perform bulk neutralization of agents. The DECON concept can be ...

    SBIR Phase II 2011 Department of DefenseDefense Threat Reduction Agency
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