Award Data

Abstract CD CD L is a key target for immunomodulation due to its central role in controlling the activation of the immune system This well studied immune switch has been the focus of extensive drug development for over two decades The validation of this drug target consists of reproducible and robust data using rodent and NHP models of chronic inflammation autoimmune disease and organ ...

DESCRIPTION provided by applicant Aging populations have become a key target for therapeutics developers particularly for indications impacting cognitive function Conditions such as Alzheimerandapos s disease and vascular dementia affect the quality of life of aging Americans largely due to their impact on cognitive function with insufficient therapeutic options Recent reports indicate tha ...

DESCRIPTION provided by applicant Hearing loss is a leading public health concern with about of American adults reporting some degree of impairment Of those fewer than seek help for their condition for a variety of reasons To address this issue the National Institue of Deafness and Other Communication Disorders NIDCD is seeking solutions to improve hearing healthcare access and l ...

DESCRIPTION provided by applicant Chromatin immunoprecipitation ChIP is one of the core methods in the study of epigenetic regulation of gene expression Analytical methods such as qPCR microarray and next generation sequencing NGS have increased throughput but not the reliability of ChIP datasets Using state of the art reagents ChIP is at best semi quantitative and at worst unreprese ...

DESCRIPTION provided by applicant Anterior cruciate ligament ACL injuries are a significant problem for athletes and the prevalence has increased exponentially due to the fold increase in sports participation by women Despite demonstrated ability to decrease injury rates through the use of neuromuscular training programs the incidence of ACL injuries remains high due to poor adoption ...

DESCRIPTION provided by applicant In his directorandapos s blog Dr Insel Director of NIMH described new directions for research andquot W e need to stop thinking about moving research to practice and start thinking about moving practice to research The idea is simple understand what works in the real world of practice by using scientific methods like randomization and statistical comp ...

DESCRIPTION provided by applicant The current prevalence of Autism Spectrum Disorder is in children and of these children do not have an intellectual disability ASDwoID Individuals with ASDwoID are at considerable risk for maladaptive adult outcomes e g un or underemployment and executive functioning EF impairments significantly contribute to this risk Unstuck and On Targe ...

DESCRIPTION provided by applicant Data collection for clinical behavioral and social research has traditionally been accomplished via paper and pencil forms collected in person by telephone or through the mail however recent technological advances have resulted in a multitude of online data collection systems DCS that deploy measures and collect data online More than of all data co ...

DESCRIPTION provided by applicant The safe and simple self sterilizing pouch system with its INNOVATIVE sterilant releasing plastic insert is ideal for STERILIZATION of all medical items especially heat and moisture sensitive medical products The product has numerous applications both commercially as well as hospital and in home healthcare applications Virtually any heat source can be use ...

Abstract For the first time it is possible to directly visualize a radiation beam hitting a patientandapos s tissue or high resolution imaging of radiation delivery in water tank phantoms using Cherenkov emission imaging This allows the opportunity to do pre treatment verification at high resolution with real time video of a test phantom prior to delivery to the patient Radiotherapy has a di ...