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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A Novel Microfludic Device for Drug Toxicity Studies

    SBC: CFD RESEARCH CORPORATION            Topic: CBD10103

    Current drug discovery and development efforts are severely limited by expensive animal trials and oversimplified in vitro models. Results obtained from in vitro models are not predictive of in vivo toxicity owing to significant difference from the in vivo physiological conditions. In this context, we propose to develop and demonstrate a novel microfluidic device that reproduces the physiological ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  2. Blood Brain Barrier Drug Delivery of Therapeutics for Chemical Warfare Agents

    SBC: IMPEL NEUROPHARMA, INC.            Topic: CBD10109

    Technical Abstract Impel NeuroPharma has developed a novel non-invasive delivery system, the POD device that targets drug to the upper third of the nasal cavity which results in direct and rapid transport of drug to the CNS via the olfactory perineural pathways, effectively bypassing the BBB. In Phase I of this research contract Impel successfully characterized and tested both an aqueous and a ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  3. Critical Data Processing for Chemical Warfare Simulant Field Testing – Advanced Data Fusion

    SBC: Torch Technologies, Inc.            Topic: CBD05110

    In this Phase II SBIR project for the Army CBD, Torch Technologies of Huntsville, AL, will develop and demonstrate a fully operational prototype of its Advanced Chemical Release Evaluation System for fusing measurements of the concentration of clouds resulting from chemical releases. The ability to evaluate the performance of a stand-off detector during development depends on the ability to accura ...

    SBIR Phase II 2006 Department of DefenseOffice for Chemical and Biological Defense
  4. Handheld FT-IR/Photoacoustic Chemical Agent Detector

    SBC: MANNING APPLIED TECHNOLOGY            Topic: CBD05112

    Manning Applied Technology proposes development of the MP-100 handheld FT-infrared photoacoustic chemical agent detector, following a highly successful Phase I effort. Chemical attacks and accidents can be mitigated partially by cost-effective sensors. High priority programs will benefit from a sensor compliant to Joint Warning & Reporting Network (JWARN) standards. The device is ideally suited to ...

    SBIR Phase II 2006 Department of DefenseOffice for Chemical and Biological Defense
  5. Microfluidic High-throughput Platform for Determining Kinetic Constants of Enzyme Variants

    SBC: CFD RESEARCH CORPORATION            Topic: CBD10107

    Current high-throughput platforms rely on labeled substrates that produce detectable spectroscopic signals upon reaction for monitoring enzyme catalytic activity. Add to that the high price tag for these instruments, ranging from several hundred thousand to millions of dollars, and there is a clear need for alternate solutions for a label-free, low-cost, high-throughput enzyme screening platform. ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  6. Tomographic Nanoscopy for Pathogen Identification

    SBC: SOLID STATE SCIENTIFIC CORPORATION            Topic: CBD171003

    This Phase II effort prototypes a minimal volume microscope designed to allow for a 2-D digital holographic imaging concurrent with field of view spectral content at video frame rates. The use of a laser driven IR dual beam frequency comb, coincident with the optical beam path required for a digital holographic image, will allow rapid acquisition of both the spatial and the spectral content associ ...

    SBIR Phase II 2019 Department of DefenseOffice for Chemical and Biological Defense
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