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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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A Novel Microfludic Device for Drug Toxicity Studies
SBC: CFD RESEARCH CORPORATION Topic: CBD10103Current drug discovery and development efforts are severely limited by expensive animal trials and oversimplified in vitro models. Results obtained from in vitro models are not predictive of in vivo toxicity owing to significant difference from the in vivo physiological conditions. In this context, we propose to develop and demonstrate a novel microfluidic device that reproduces the physiological ...
SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense -
Dermal Medical Countermeasures for Chemical Weapons Exposure
SBC: ZYMERON CORPORATION Topic: CBD161003The skin is the first line of defense against chemical warfare agents including nerve agents and toxic industrial chemicals, providing a possible barrier or delay to systemic distribution. Some chemicals also can act directly on the skin including the vesicants sulfur mustard and lewisite. Early and rapid skin decontamination is extremely important following exposure to CWAs and TICs because it de ...
SBIR Phase II 2018 Department of DefenseOffice for Chemical and Biological Defense -
Development of a Database Management System to Enable Rapid, Efficient Assay Design for Use in Detection and Diagnosis of Human Exposure to Biological
SBC: CFD RESEARCH CORPORATION Topic: CBD07114Increases in amount and diversity of high-throughput data presents tremendous organizational and analysis challenges to researchers. Our objective in this effort is to address these challenges by designing and implementing a database management system (cipherDB) for the storage, management, analysis, and visualization of diverse biological data types. The Phase I design and implementation of ciphe ...
SBIR Phase II 2008 Department of DefenseOffice for Chemical and Biological Defense -
Generic Adsorptive Carbon Residual Life Indicator
SBC: MORPHIX TECHNOLOGIES, INC. Topic: CBD07103Generic residual life indicator technology developed under PI effort will be matured through reduction of COTS items used in the breadboard design to a miniaturized brassboard system capable of detecting agent saturation front migration through a sorbent. The capability of this brassboard system to detect representative agents from several classes will be demonstrated along with the ability to pr ...
SBIR Phase II 2008 Department of DefenseOffice for Chemical and Biological Defense -
Hermetic Seals for Chemical/Biological Protective Garments
SBC: CREARE LLC Topic: CBD13109Interfaces on existing military chemical/biological protection garments are not designed to fully eliminate macroscopic and microscopic air gaps at folds, fabric surfaces, or hook-and-loop closures, and thus do not provide a hermetic barrier against exposure. Creare is developing hermetic garment closure systems that seal macroscopic and microscopic gaps at interfaces and closures and provide high ...
SBIR Phase II 2018 Department of DefenseOffice for Chemical and Biological Defense -
Infectious Disease Diagnostics and Differentiation of Viral vs. Bacterial Infections for Point ofCare Applications
SBC: GENECAPTURE, INC. Topic: CBD15C001GeneCapture, Inc. is proposing to develop a rapid in vitro diagnostic prototype using our patented molecular-based CAPTURE (ConfirmActive Pathogens Through Unamplified RNA Expression) assay. Based on the results and experience gained in our Phase I STTR contractHDTRA1-16C-0061: Infectious Disease Diagnostics and Differentiation of Viral vs. Bacterial Infections for Point of Care Applications, we p ...
STTR Phase II 2018 Department of DefenseOffice for Chemical and Biological Defense -
Lightweight, Efficient Blower for Personal Air Ventilation System
SBC: CREARE LLC Topic: CBD07115A personal air ventilation system (PAVS) can dramatically improve the environment inside chemical/biological protective clothing, protecting the health and safety of soldiers and enabling peak physical/mental performance for long periods. However, existing air blowers that can produce the flow rate and pressure drop needed for a PAVS are too heavy, inefficient, and noisy for a man-portable system ...
SBIR Phase II 2008 Department of DefenseOffice for Chemical and Biological Defense -
Medical Countermeasure Development for Viral Induced Encephalitis Using Single DomainAntibodies
SBC: ABZYME THERAPEUTICS LLC Topic: CBD161004Alphaviruses, infection with which may cause encephalitis and death, are recognized as potential biological warfare agents. There are noapproved medical countermeasures against Alphaviruses. In Phase I, using Abzymes proprietary in vivo Self-Diversifying Camelid SingleDomain Antibody Library (SDALib) platform, broadly reactive single domain camelid VHH antibodies against equine encephalitis viral ...
SBIR Phase II 2018 Department of DefenseOffice for Chemical and Biological Defense -
Microfiber-Based Closures with Hermetic Sealing for Chem Bio Protective Garments
SBC: NANOGRIPTECH Topic: CBD13109Future engagements (especially with near-peer threats) present the possibility of a wide range of anticipated operational situations involving the presence of chemical threat agents. With this, deployment of Military Working Dogs (MWDs) is likely. This creates a situational awareness that MWDs are potentially at risk from exposure to a wide range of hazardous chemicals. Potential threat agents inc ...
SBIR Phase II 2018 Department of DefenseOffice for Chemical and Biological Defense -
Microfluidic High-throughput Platform for Determining Kinetic Constants of Enzyme Variants
SBC: CFD RESEARCH CORPORATION Topic: CBD10107Current high-throughput platforms rely on labeled substrates that produce detectable spectroscopic signals upon reaction for monitoring enzyme catalytic activity. Add to that the high price tag for these instruments, ranging from several hundred thousand to millions of dollars, and there is a clear need for alternate solutions for a label-free, low-cost, high-throughput enzyme screening platform. ...
SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense